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Biomedical subjects

J Kawamura

Publications and source records attributed to J Kawamura.

At least 343 records · Page 19Linked to original sources

Paired anterior spinal arteries in a case of locked-in syndrome.

Paired anterior spinal arteries have rarely been demonstrated angiographically, although several anatomical studies have shown that they are not uncommonly observed. This report describes the angiographic and autopsy findings of such a variation, which was observed in a 65-year-old man with a locked-in syndrome. The paired trunks of the anterior spinal artery were visualized in a retrograde fashion through the left inferior thyroid artery and a radical branch at the 5th cervical level by left retrograde brachial angiography. The uppermost segments of either vertebral artery and the lower portion of the basilar artery were opacified through these channels. The autopsy confirmed the paired trunks of the anterior spinal artery, occlusion of the vertebral arteries just caudal to the origin of the main branches of the anterior spinal artery, and an old infarct involving the pontine tegmentum and cerebellum.

Aged↗

Hadju-Cheney syndrome. Report of a non-familial case.

The case of a 24-year-old man with Hadju-Cheney syndrome is reported. No similar disease occurred in his family. Inverted and bullous tips of fingers were noted at age 9 and protruded occipital bone at age 10. He complained on left facial spasm and facial tics for 1 year. Examination revealed a man of short stature, with a brachycephalic skull and hypertelorism. Radiologically there was an extreme degree of basilar impression with the basal angle of 180 degrees, demineralized spinal vertebrae, and acro-osteolysis. Both bone and CT scans demonstrated the abnormalities of the skull clearly. The basilar artery ran almost horizontally on angiography. He gradually deteriorated neurologically with bulbar, pyramidal and cerebellar signs and symptoms. Review of the literature revealed at least ten non-familial and nine familial cases of this disorder. It is considered that this syndrome is a genetically determined generalized dysplastic bone disorder.

Adult↗

Prepontine epithelium-lined cyst. Case report.

A 30-year-old woman presented with recurrent episodes of severe headache associated with visual disturbances. Neurological examination showed minimal neurological defects. Angiography, computerized tomography, and radioisotope cisternography revealed a large cyst in the prepontine region, which did not communicate with either the subarachnoid space or the ventricular system. Histologically, the cyst was lined by columnar and/or cuboidal cells, which contained materials positive on periodic acid-Schiff staining. Ultrastructurally, there were two types of cells, ciliated and noncillated. Characteristic findings were continuous basement membrane, microvilli covered with electron-dense material, several intercellular junctional devices, and an open intercellular space which was occasionally filled with a migrating cell. These findings would support the view that the epithelial cyst with such features was derived from endodermal tissues rather than from neuroepithelium. Electron microscopic examination is indispensable in making a correct diagnosis of intracranial cysts.

Adult↗

Hypertension with elevated renal vein renin secondary to unilateral hydronephrosis.

A case of hypertension secondary to unilateral hydronephrosis is reported. Renin levels were elevated in peripheral veins and in the renal vein draining the affected kidney. An infusion of angiotensin II analogue resulted in a decrease in blood pressure. After nephrectomy, blood pressure and peripheral plasma renin activity returned to normal. Renal vein renin and angiotensin II analogue studies were useful in the diagnosis and evaluation of curability by surgery in this case.

Adult↗