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Biomedical subjects

J K Oh

Publications and source records attributed to J K Oh.

111 records · Page 7Linked to original sources

Effect of ambient illumination on the spatial properties of the center and surround of Y-cell receptive fields.

The primary goal of this study was to expand the description of the filtering properties of the Y-cell receptive field, by quantitatively characterizing the spatial filtering properties of the receptive field's center-and-surround components as a function of adapting light level. A range of more than five orders of magnitude in retinal illuminance were covered, including the vast majority of the cat's functional range of vision. Recordings were taken from optic tract fibers of Y cells in cats under general anesthesia. Sinusoidal gratings and a stimulus designed to selectively probe the properties of the surround mechanism were used. The cells' responses to these stimuli were fit to a Gaussian center-surround receptive-field model, in which six parameters define the properties of the center and surround. Fits were made independently to data collected at each light level and changes in the values of the model's parameters with illuminance are reported. A set of equations that summarize the changes in parameter values is given. From these summary equations, reasonable estimates of the parameters' values can be determined across a wide range of illuminances. Hence, a quantitative model of the spatial properties of the center and surround of the Y-cell receptive field can now be derived from these equations for most of the levels of retinal illuminance experienced by a Y cell. The consistency between the description provided by our equations and results from earlier work is considered.

Animals↗

The cat's pupillary light response under urethane anesthesia.

Pupillary area was measured in urethane-anesthetized cats as a function of retinal illuminance. When appropriate corrections are made for differences in experimental procedures, it was found that the pupillary response of the urethane-anesthetized cat's eyes to light was basically unchanged from that of the alert behaving cat. This preparation may therefore be a very satisfactory one in which to study the pupillary response pathway in a higher mammal.

Anesthesia, Intravenous↗

Relationship between skin phototype and MED in Korean, brown skin.

The Fitzpatrick skin classification has been a useful method to categorize cutaneous sensitivity to ultraviolet radiation (UVR), although it was based originally on responses in white skin. Because the relevance of this phototype in brown skin is in question, we investigated skin phototypes of university students by a self-reporting questionnaire and measured their MEDs in Korean, brown skin. After studying our explanation of the definition of Fitzpatrick skin types, 707 Korean university students answered the questionnaire. We then measured UVB MEDs in 156 randomly selected male students. The order of frequency of skin type was type III (55.0%), IV (29.0%), and V (12.3%) by the questionnaire, with the sun sensitive categories (types I and II) reported only for 3.7%. There was no significant difference in MEDs between types IV and V, and the mean MED of each skin type did not show a monotonic increase with increasing skin type. Subjects with MEDs of 70-90 mJ/cm2 (corresponding to the MED of skin type V, as proposed by Pathak & Fitzpatrick) represented about half or more of the subjects in all categories, even types II and III. Subjects with MEDs lower than 60 mJ/cm2 were more prevalent in types II and III compared with types IV and V. We suggest that there is at best a weak relationship between the skin types, by the Fitzpatrick method, and MEDs in Korean, brown skin.

Adult↗