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Biomedical subjects

J K Lauber

Publications and source records attributed to J K Lauber.

At least 37 records · Page 2Linked to original sources
PubMed1979

The water provocative test in preglaucomatous chickens.

Our ability to induce glaucoma in birds provides an experimental system for exploring the mechanisms involved in the provocative water test. Waters loads of a level comparable to those used clinically produced larger intraocular pressure (IOP) changes in preglaucomatous and glaucomatous birds than in control birds. The magnitude of the response corresponded to the level of IOP before testing, that is, to the severity of the glaucoma. Changes in systemic blood pressure were not involved in the response. While hyotonicity of plasma may be the systemic determinant, the normal range of variation in this factor does not allow us at present to consider this a causal relationship.

Animals↗
PubMed1979

Eye enlargement in birds induced by dim light.

We here report changes in eye weight and other measurements, in chickens reared in dim light. These effects are distinguished from those seen in light-induced avian glaucoma (brought on by exposure to continuous light). We confirm and extend the results of Berkovitz and Harrison on the dim light effect, but we differ from Axmith and Morin, who were apparently unable to reproduce light-induced avian glaucoma. We cannot yet offer an explanation as to the mechanism(s) of eye damage in either light-induced avian glaucoma or dim light-induced macrophthalmos.

Animals↗
PubMed1978

Biochemical studies of the chicken vitreous in light-induced avian glaucoma.

Changes in several macromolecular species of the vitreous are traced during post-hatching development in normal and glaucomatous avian eyes. 1. Total gel vitreous, and its hydroxyproline content, change little during development. 2. Sol vitreous increases parallel eye growth, the concentrations of hexosamine and hexuronic acid remaining constant. 3. In light-induced avian glaucoma, the sol, but not the gel, is further increased, although the hyaluronic acid components are not diluted in the pathologically enlarged eye.

Animals↗