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Biomedical subjects

J Jorgensen

Publications and source records attributed to J Jorgensen.

At least 55 records · Page 3Linked to original sources

Renin inactivation in vitro in non-pregnant rabbit uterine and kidney tissue.

In slices of non-pregnant rabbit uterus, renin was gradually inactivated during incubation in vitro at 37 degrees C, for 44 hours. The percentual rate of inactivation (40 per cent/44 hours) was, however, only about half of that found in uterine slices from pregnant and post-partum animals despite the fact that the endogenous renin concentration was much lower in the non-pregnant uteri. In control experiments with kidneys with the same high renin content as in the pregnant uteri only about 30 per cent of the renin was inactivated in 44 hours.

Animals↗

Intraspinal tumours in the first two decades of life. Clinical and radiological features.

Twenty-eight patients with spinal tumours (11 malignant and 17 benign) detected in their first two decades of life have been reviewed. Twenty-six of the 28 patients had neurological disturbances, and a significant difference in the duration of debut symptoms in the benign and malignant groups could be demonstrated. X-ray survey was positive in 11 cases in the benign group and in three cases in the malignant group.

Adolescent↗

Acid activation of renin in rabbit uterus.

During the first 2 days post-partum there is a rapid fall in the uterine renin content of the rabbit. A similar loss of renin can be reproduced in vitro when pregnant and post-partum and to a lesser degree non-pregnant uterine tissue slices are incubated at pH 7.4 at 37 degrees C. When a secondary incubation of these previously incubated preparations is performed at pH 4.8 an activation of renin is seen. There was not an inverse correlation between the amounts of renin lost during the primary incubation at pH 7.4 and the amounts of renin activated during the secondary incubation at pH 4.8. In similarly incubated preparations of kidney cortex, where only a small per cent of the initial renin content is lost during the primary incubation at pH 7.4, no activatable renin is seen.

Animals↗

A clinical and radiological study of chronic lower spinal arachnoiditis.

A critical evaluation revealed no distinct clinical complex of symptoms related to the radiological picture of chronic adhesive arachnoiditis in the lower lumbar sac in 72 patients. In all cases the arachnoiditis was diagnosed by myelography with water soluble contrast media and, in 16 cases, verified by operation and microscopy. The assumed cause of arachnoiditis was, in more than half of the cases, the combination of myelography and operation in close relation, and, in ten cases, a previous operation.

Adolescent↗

Data on the HL-A linkage group.

Lod scores from a study in 229 families of the linkage relations of HL-A-PGM3 to 19 marker loci and cystic fibrosis are reported. The data exclude that ADA belongs to this linkage group while they give weak support for the inclusion of P. There is weak evidence for linkage of cystic fibrosis to PGM3, but none for linkage to HL-A. No new suggestive linkages appeared.

Blood Group Antigens↗

Radiography of laryngeal carcinoma. Assessment of value.

The value of various radiographic methods (except laryngography) in laryngeal carcinoma was assessed in a material of 71 patients. Radiography proved of no value in T1 and T2 tumours if a satisfactory clinical examination could be performed but gave valuable information in recurrences as well as in T3 and T4 cases.

Adult↗