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Biomedical subjects

J Jagger

Publications and source records attributed to J Jagger.

122 records · Page 7Linked to original sources
PubMed1969

Action spectrum for growth delay induced in Escherichia coli B-r by far-ultraviolet radiation.

An action spectrum for growth delay induced in Escherichia coli B/r by far-ultraviolet radiation (230 to 295 nm) was obtained. It resembles the action spectrum for killing obtained in the same experiments, indicating that the chromophore for growth delay is probably the same as the chromophore for killing. Another action spectrum for killing, obtained under conditions more suitable for chromophore identification, suggests that nucleic acid, either deoxyribonucleic acid or ribonucleic acid, is the chromophore for growth delay induced by far ultraviolet. Isoprenoid quinones, which seem to be important chromophores for growth delay induced by near-ultraviolet radiation (above 300 nm), appear to play a negligible role in growth delay induced by wavelengths below 300 nm.

DNA, Bacterial↗
PubMed1967

Division delay induced in Escherichia coli by near-ultraviolet radiation.

Beams of near-ultraviolet radiation at several principal emission lines of a mercury arc were isolated with a grating monochromator and directed upon cell suspensions. During subsequent incubation at room temperature in Nutrient Broth, the population was studied by removing samples and obtaining cell numbers and cell size distributions with an electronic cell counter. Division delay without lethality was observed. The shapes of the dose-response curves for induction, the doses of near-ultraviolet radiation required, and the action spectrum for division delay were found to be similar to those for growth delay (in broth) and for photoprotection. These findings indicate that all three effects, division delay, growth delay, and photoprotection, are induced by a common type of critical event. Changes in cell size distribution in the culture during incubation in Nutrient Broth after near-ultraviolet irradiation are very similar for control and irradiated populations, although these changes occur at a much later time in the irradiated population. This indicates that, in Nutrient Broth, the population recovers completely from the inhibition of growth and division, thus justifying use of the term "delay," and suggesting that the damage is nongenetic.

Cell Division↗
PubMedDate not supplied

Epidemiology and prevention of blood and body fluid exposures among emergency department staff.

Emergency Department (ED) staff are vulnerable to occupational exposure to infectious blood and body fluids (BBF). Universal precautions are often ignored in the ED setting. Identification of body locations at high risk of BBF exposure may allow development of site specific protective garments that minimize risk and inconvenience. All permanent staff (92) in a 58,000 visit public university hospital ED with potential for BBF exposure were surveyed. Respondents estimated the number of BBF contacts sustained during the past year, describing their most recent contact in detail. Seventy-eight of 91 (85%) responded, reporting average rates of 54.1 intact skin, 1.5 nonintact skin, and .87 mucous membrane BBF contacts per full-time employee per year. Of the most recent incidents, 94% involved blood, 22% involved vomit or urine, and 11% involved saliva. Eighty-eight percent of BBF contacts were to unprotected skin or mucous membranes, either when no barrier was worn or at the gap between gloves and sleeves. Most (66%) were distal to the elbow; 13% involved the face. Use of long gloves or another continuous protective barrier from the fingers to the elbow, in addition to increased use of face masks or shields, would markedly reduce the rate of ED BBF contacts with a minimum of inconvenience.

Blood-Borne Pathogens↗
PubMedDate not supplied

Reducing blood and body fluid exposures among clinical laboratory workers. Meeting the OSHA standards.

This article examines risks and exposure patterns in clinical laboratories to help identify the most effective methods for implementing the OSHA standard for protection against bloodborne pathogens, especially hepatitis B virus and the human immunodeficiency virus. Using eye-opening figures, tables, and statistics, the authors identify areas where clinical laboratorians can improve their protection and conclude by offering three strategies for reducing blood and body fluid exposures in clinical laboratories.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Injuries from vascular access devices: high risk and preventable. Collaborative EPINet Surveillance Group.

Intravenous catheter stylets are the number one cause of needlesticks from blood-filled needles, the type of injury that is most likely to transmit bloodborne pathogens. The Exposure Prevention Information Network (EPINet, a trademark of the University of Virginia) database provides information on the characteristics of injuries from i.v. catheter stylets and on the effectiveness of safety i.v. catheters designed to prevent injuries. EPINet data show that nurses sustained three fourths of these injuries, and that injury rates declined by 84% after the introduction of a safety i.v. catheter in three study hospitals. In order to reduce the risk of bloodborne pathogen transmission to healthcare workers, especially nurses, the widespread implementation of i.v. catheters designed to prevent needlesticks should be undertaken as quickly as possible.

Catheters, Indwelling↗
PubMedDate not supplied

Central retinal vein occlusion associated with the polycystic ovarian syndrome.

We report a case of central retinal vein occlusion (CRVO) in a young woman with polycystic ovarian syndrome (PCOS). CRVO in young patients is a rare condition, frequently associated with a severe underlying systemic disorder. This is the first report of CRVO associated with documented PCOS. We discuss the therapeutic dilemma.

Adult↗