Search PubMed⌕ Search

Biomedical subjects

J J Trautlein

Publications and source records attributed to J J Trautlein.

At least 19 recordsLinked to original sources
PubMed1996

Patient allergies: role in selective use of nonionic contrast material.

PURPOSE: To determine which aspects of patient allergies allergists and immunologists would recommend for the selective use of nonionic contrast material. MATERIALS AND METHODS: A survey about allergy and the selective use of nonionic contrast material was sent to 1,017 allergists and immunologists. RESULTS: Of 287 respondents, 262 believed that a non-contrast material-related allergy alone was not an indication for use of nonionic contrast material. Most (n=219) believed that a previous serious or life-threatening reaction was the best indication and that a minor reaction was not an indication. Most respondents believed that patients with any previous reaction to contrast material should receive nonionic contrast material, steroids and then nonionic contrast material, or no contrast material at all. CONCLUSION: Use of nonionic contrast material in patients with previous non-contrast material-related allergic reactions should be limited to patients with previous serious or life-threatening reactions.

Contraindications↗
PubMed1990

The design and effectiveness of a graduate survey course in quality assurance and utilization review.

This paper reports on the design, presentation, and evaluation of a graduate university course in quality assurance and utilization review. The authors cite the need for expanded course offerings in this field and present descriptions of the course design and student participants, including program location, objectives, learning themes and content, instructor team, students, and course process. Student feedback is reported including comments on course strengths and needs, teaching methods, and learning evaluation. Additional work requirements are cited.

Curriculum↗
PubMed1987

Oral hyposensitization to poison ivy and poison oak.

We evaluated the safety and efficacy of a 1:1 mixture of pentadecylcatechol (PDC) and heptadecylcatechol (HDC) diacetate in reducing hypersensitivity to poison ivy and poison oak. The study was double-blind, parallel, randomized, and placebo controlled. The 44 subjects receiving the active drug ingested a cumulative dose of 306.5 mg over a five-week period. Subsequently, 14 patients were continued on a maintenance phase, ingesting an additional 960 mg of drug. The PDC-HDC diacetate was well tolerated, with no significant side effects. Evaluation of efficacy compared poststudy and prestudy reactions to patch tests using urushiol in doses of 0.025, 0.05, 0.125, 0.25, and 0.5 micrograms applied to the forearm. The results indicated that the induction phase as well as the maintenance phase did not induce a statistically significant hyposensitivity to urushiol, and we were thus unable to decrease sensitivity to poison ivy and poison oak in humans using orally ingested PDC-HDC diacetate.

Administration, Oral↗
PubMed1984

Malpractice in the emergency department--review of 200 cases.

Two hundred consecutive cases brought to the attention of a malpractice insurer by evidence of expected legal action were reviewed. Of these cases, 132 (66%) were attributed primarily to misdiagnosis, and 87 of these would have satisfied admission criteria. The most common error was grossly deficient examination relating to the chief complaint. Focused attention to physical examination and diagnostic skills, history taking, and minimal use of laboratory studies could have avoided the initiation of the majority of cases.

Diagnostic Errors↗
PubMed1981

Bioavailability, efficacy, and tolerance of two sustained-release theophylline dosage forms in adult patients with bronchial asthma.

Twenty otherwise health adults with a diagnosis of reversible obstructive airways disease were treated for one month in a single-blind crossover study with approximately equivalent doses of Elixophyllin SR capsules or Theo-Dur tablets. Both products provided evidence of efficacy by improvement in pulmonary function tests, and both were well tolerated. There were no significant differences between the two products with regard to bioavailability, efficacy, or tolerance. Both dosage forms appeared to have similar kinetic properties within the context of the study.

Adolescent↗
PubMed1981

Tartrazine (FD & C yellow #5) anaphylaxis: a case report.

Tartrazine dye has been implicated in a variety of adverse reactions. There is a high correlation between aspirin sensitivity and tartrazine sensitivity but the reverse is exceedingly rare. Herewith is presented a case where repeated occult exposures to tartrazine yellow dye in a patient who could take aspirin with impunity was uncovered by a deduction. The ubiquitous nature and protean manifestations of dye sensitivity are discussed.

Adult↗
PubMed1979

Posttraumatic aneurysms of the hand.

Aneurysms should be suspected in patients with a mass in the hand following either open or closed trauma. Posttraumatic aneurysms are classified as true or false. False aneurysms usually result from penetrating trauma and can occur in any disrupted vessel. In contrast, true aneurysms usually occur in either the thenar or hypothenar eminence a few weeks following closed hand injuries. Pulsations may be evident. Symptoms are coolness or paresthesia of the digits and dull pain aggravated by exercise. A positive Allen's test is a helpful confirmatory sign in diagnosis. Treatment is surgical with resection of the aneurysm and primary anastomosis or vein graft when possible.

Adult↗
PubMed1977

Immunosuppression and human cancer: role of prostaglandins.

Prostaglandins, unsaturated fatty acid derivatives with diversified pharmacologic activity, have been implicated in the pathophysiology of many diseases. Prostaglandin E (PGE) levels were measured by radioimmunoassay in the plasma of 41 normocalcemic patients with various stages of malignancies. Delayed hypersensitivity was assessed by a battery of six recall skin test antigens (ST) and by Dinitrochlorobenzene (DNCB) sensitization and challenge. Twenty-five patients with one or more positive skin tests had a mean PGE level of 87+/-8 pg/ml, whereas 16 patients with negative ST had a mean PGE level of 96+/-12 pg/ml. Twenty-one DNCB negative patients had a mean PGE level of 98+/-12 pg/ml and eight totally anergic patients had a mean PGE of 96+/-12 pg/ml. All PGE values were within the normal range and there was no statistical difference between the four groups. (p less than 0.1). We concluded that circulating PGE does not correlate with the non-specific immunosuppression seen in cancer patients.

Adult↗