Biomedical subjects

J J Sullivan

Publications and source records attributed to J J Sullivan.

114 records · Page 7Linked to original sources

PubMedDate not supplied

Return to work as a measure of outcome in adults hospitalized for acute burn treatment.

Rehabilitation of patients with burn injuries is receiving renewed interest because survival has improved, and health reform has mandated outcomes assessment. To determine factors affecting return to work, a survey was conducted among 234 employed patients treated from 1986 through 1993. The mean burn size was 13.3% total body surface area. Patients returned to work in a mean of 14.3 weeks; a number initially returned to light-duty or part-time jobs as a "bridge" to full-time employment. Length of hospitalization, number of surgeries, total and full-thickness burn size, and subjective assessments by patients of their functional ability correlated with time off work. Patients with health insurance were more likely to resume work than was expected, whereas those covered by Medicaid and those involved in injury-related lawsuits were less likely to return to work. It is hoped that this information can be used to design interventions aimed at improving this outcome of burn treatment.

Acute Disease↗

PubMedDate not supplied

Predicting infant apgar scores.

This study identified psychologic and sociologic phenomena that affect a woman during pregnancy which, when associated with physical factors, result in poor neonatal outcome for the infant, as measured by the Apgar score at five minutes after birth. The Utah Test Appraising Health (UTAH) was administered to 51 pregnant women during the second or third trimester of pregnancy. Data measuring maternal and infant outcomes were collected postdelivery. A significant correlation was found between maternal stress up to six months before administration of the UTAH questionnaire and the five-minute infant Apgar score (r = -.2787, p less than or equal to .05). The stress score was combined with past pregnancy complications, pregnancy symptoms during the first and third trimesters, and illness-proneness in a regression equation. The total multiple correlation coefficient was .8979, with stress X past pregnancy complications contributing most to the prediction equation. When stress and past pregnancy complications were controlled, the partial correlation value was -.8001. The data were consistent with the hypothesis that stress during pregnancy is an activator of physical illness processes in the mother, and, when combined with these variables, is related to neonatal outcome, as measured by the infant Apgar score at five minutes.

Adaptation, Psychological↗

PubMedDate not supplied

Disseminated spiked hyperkeratosis.

Multiple small hyperkeratoses were observed in a 42-year-old woman. They had first appeared in early adult life. There was a history of an apparently identical disorder affecting her father, her brother, and her brother's son. A similar condition has been described in four previous reports in which seven individual cases have been documented. Four had a positive family history, bringing the total number of previously known cases to 14. The disorder is characterized by the development in early adult life of widely disseminated small spikes of keratin that are unrelated to hair follicles. Microscopic examination shows digitate orthokeratosis with moderate epidermal cell hyperplasia and a normal underlying dermis.

Adult↗

PubMedDate not supplied

Determination of total sulfite in shrimp, potatoes, dried pineapple, and white wine by flow injection analysis: collaborative study.

A method for the determination of total sulfite in shrimp, potatoes, dried pineapple, and white wine by flow injection analysis (FIA) was collaboratively studied by 8 laboratories. In the method, the sample solution is reacted with sodium hydroxide to liberate aldehyde-bound sulfite. The sample stream is acidified to produce SO2 gas, which diffuses across a Teflon membrane in the gas diffusion cell into a flowing stream of malachite green. The degree of discoloration of the malachite green is proportional to the amount of sulfite in the sample solution. Red wine was included in the study but interlaboratory precision for these samples was not satisfactory and correlation with Monier-Williams results was poor. The present method is not recommended for use with these samples. For shrimp, potatoes, dried pineapple, and white wine, average reproducibility (RSDR) of results was 25% for samples at 10 ppm SO2 and 10% for samples at greater than 50 ppm. Overall average reproducibility was 14%. Recoveries of sulfite added to samples averaged 80%. Comparison of FIA with the Monier-Williams method indicated comparable results by the 2 methods. The FIA method has been adopted official first action for determination of greater than or equal to 5 ppm total sulfite in shrimp, potatoes, dried pineapple, and white wine.

Animals↗

PubMedDate not supplied

Determination of free (pH 2.2) sulfite in wines by flow injection analysis: collaborative study.

A method for the determination of free sulfite in wine by flow injection analysis (FIA) is described. The method involves liberation of sulfur dioxide from the wine at pH 2.2, with detection by decolorization of a malachite green solution. The method was collaboratively studied, and the results indicated an average reproducibility of 12% for white wine samples (average level 12.1 ppm SO2) and 26% for red wine samples (average level 3.1 ppm). When the FIA method was compared to an aeration/oxidation method, the results indicated a high degree of correlation between the 2 methods. The FIA method has been adopted by AOAC official first action.

Hydrogen-Ion Concentration↗

PubMedDate not supplied

Determination of sulfite in food by flow injection analysis.

A method is described for the determination of sulfite levels in food products by flow injection analysis (FIA). The method is based on the decolorization of malachite green by SO2, which is isolated from the flowing sample stream by means of a gas diffusion cell. The FIA method has a detection limit in food sample extracts of 0.1 ppm SO2 (3 times peak height of blank), which corresponds to 1-10 ppm SO2 in a food product, depending on the extraction procedure used. At the 5 ppm SO2 level in a food extract, the precision of replicate injections is +/- 1-2%. The method was tested on a variety of both sulfite-treated and untreated food products and the results compared favorably with those obtained by the Monier-Williams, colorimetric (pararosaniline), and enzymatic (sulfite oxidase) methods. The average differences from the FIA results were 19, 11, and 12%, respectively, for those samples (n = 12) above 50 ppm SO2. At lower levels the results were somewhat more erratic due to inaccuracies of the various methods at low concentrations.

Colorimetry↗