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Biomedical subjects

J J Shea

Publications and source records attributed to J J Shea.

At least 73 records · Page 4Linked to original sources

Congenital cholesteatoma of the petrous pyramid.

A 20-year follow-up was done on a patient with a large congenital cholesteatoma of the petrous apex. The patient was treated successfully with marsupialization through a radical mastoidectomy and sphenoid sinusotomy. Cranial computed tomography and magnetic resonance imaging demonstrated continued cholesteatoma growth. Bone-conduction thresholds remained normal despite replacement of the internal auditory canal by cholesteatoma matrix. The patient continues to have chronic otorrhea, but is otherwise asymptomatic.

Adolescent↗

Effect of urea on endolymphatic hydrops in guinea pigs.

The morphological changes of the inner ear were observed after intravenous administration of 2 g/kg of urea to the guinea pigs with endolymphatic hydrops which had previously been produced by injecting 10% silver nitrate solution into the endolymphatic sac. They showed membranous collapse extensively in the saccule, moderately in the lower turns of the cochlea and less in the upper turns and the utricle. Because of these changes, it is reasonable to assume that urea is causing the endolymph to be reabsorbed in the endolymphatic duct. Furthermore, the effect of urea seemed to depend on the pathological condition of the duct which sometimes showed a varying degree of atrophied change after silver nitrate injection.

Animals↗

Peg-tip fixation of Plasti-Pore TORP.

When inserted into a small hole drilled in the footplate, the peg-tipped Plasti-Pore TORP has given good hearing gain, without complications in a small series of patients.

Ear Ossicles↗

Medical treatment of tinnitus.

Tinnitus is the subjective perception of sound that does not exist. Tinnitus is caused by an altered discharge in the auditory pathway from hair cell to cortex and back. Intravenous Xylocaine acts by blocking 10% of the transmission through each synapse, having more effect on the slow multisynaptic pathway through the reticular formation than the rapid pathway to have more effect on the low frequency slow pathway tinnitus than the rapid pathway high frequency tinnitus. Tocainide, the oral amide of Xylocaine, is of great value in the treatment of tinnitus responsive to intravenous Xylocaine.

Humans↗

Intensity and frequency of sound levels from cordless telephones. A pediatric alert.

Recent reports have established that the ring of a cordless telephone is sufficient to produce hearing loss. In the present study, the intensity and frequency spectrum of the ring signal for three cordless telephones known to be involved in reported cases of acoustic trauma are presented. The potential hazard to hearing is reviewed, the implications for the pediatric community discussed, and the recommendation made that unmodified cordless telephones be kept out of the reach of children.

Acoustics↗

Recurrence rate of partially resected acoustic tumors.

Thirty-three (16.5%) of the first 200 patients who presented to the Otologic Medical Group with acoustic tumors underwent surgery for their subtotal removal. These 33 patients, operated on between 1964 and 1967, were followed for clinical evidence of recurrent tumor for a period ranging from 2 to 20 years. Twelve patients required further surgery for recurrent tumor and three of these repeat surgery patients died as a result of their tumors. Case reports of six patients who underwent partial resection are presented with recent computed cranial tomographic follow-up.

Adult↗

Reconstruction of the posterior canal wall with Proplast.

Many ears with prior radical or modified radical mastoidectomy operations can be rehabilitated by reconstruction of the posterior canal wall with the porous biocompatible implant material Proplast. Many techniques have been advanced for reconstruction of the posterior canal wall and/or obliteration of the mastoid bowl. We prefer reconstruction of the posterior canal wall to obliteration of the mastoid bowl on the theoretical grounds that with obliteration you lose the pneumatic buffer of the mastoid air cell system and you might be burying infection and/or cholesteatoma in the depths of the mastoid. In this article we shall present our results with elimination of the open mastoid bowl by reconstruction of the posterior canal wall with Proplast. A retrospective study of 83 consecutive patients who underwent reconstruction of the posterior canal wall with Proplast during the 5-year period 1974 to 1978 was undertaken. The surgical technique consisted of rebuilding the tympanic membrane, when necessary, repairing the ossicular chain, when necessary, and reconstructing the posterior canal wall. The overall success rate for the posterior canal wall reconstructions was 46% (38 of 83). However, after modifications were made in the technique, especially in the use of thicker fascia and/or perichondria and periosteum over the Proplast, the success rate increased dramatically to 68% (19 of 28).

Ear Canal↗

Autoimmunity and inner ear disorders: an immune-complex mediated sensorineural hearing loss.

An immune-complex mediated form of autoimmune disease is described with the inner ear as one of its target organs. Around 40 dB bilateral sensorineural hearing loss improved on short-term corticosteroid therapy to normal levels. This case report is presented against the background of a general survey on autoimmunity and inner ear diseases. Cellular and humoral immune reactions may be etiologic moments in an audiovestibular dysfunction of autoimmune character.

Adolescent↗

Closure of dural defects with proplast.

Defects of the dura mater, which are a source of cerebral spinal fluid leakage, may be produced by trauma and otologic and neurosurgical operations. Proplast was evaluated as a graft material to close dural defects in three animal models (cats). For comparison, temporalis fascia was similarly evaluated in an additional three cats. Microsurgical techniques were utilized to close the defects, and both materials successfully prevented cerebral spinal fluid leakage. Proplast, however, was judged superior when studied microscopically at three months. There was ingrowth of living dura into the Proplast and no evidence of inflammatory reaction.

Animals↗

Temporal bone findings in trisomy 13 with cyclopia.

Temporal bone findings in a fetus with trisomy 13 syndrome and cyclopia may be histopathologically characterized by the dysplasia of bony and membranous labyrinth and of the nervous system. In the left ear, there was a shortened cochlea housing a malformed Corti's organ appearing as a ribbonlike structure, an unexpected canal running obliquely through the scala tympani, a peculiar shape of the utricular macula and posterior canal crista, and a delayed ossifying process in the otic capsule. The poor development of the structures in the seventh and eighth nerves and their ganglions was observed in both ears. The type of anomaly can be classified as Mondini or Mondini-Alexander. The several anomalies might involve the organs that begin to develop during the period from five to eight gestational weeks.

Abnormalities, Severe Teratoid↗

Malleus Teflon piston prosthesis.

The malleus Teflon piston prosthesis is very useful to reconstruct the sound conducting mechanism of the middle ear in absent or inadequate incus, congenital malformation of the middle ear, and epitympanic fixation of the incus and/or malleus. It has a thin-walled loop at its upper end to lessen the tendency for ulceration of the overlying drum with an inside diameter of 1 mm to fit around the mid portion of the handle of the malleus at an angle of 30 degrees to the shaft of the prosthesis. There is a cut in the distal part of the loop through which it is snapped onto the handle of the malleus after it is separated from the drum. Examples of the various situations in which this prosthesis has been used will be shown together with the results regarding hearing gain, complications, and other problems. Those situations in which the prosthesis was used in 1972 will be reviewed to give a 10-year follow-up, plus some notable examples of other uses of the prosthesis from other times.

Ear Ossicles↗