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Biomedical subjects

J J Ratey

Publications and source records attributed to J J Ratey.

29 records · Page 2Linked to original sources
PubMed1986

The concept of noise.

"Noise" is a term we are using to describe a complex and distressing aspect of the bodily and cognitive experience of many very ill psychiatric patients. By "noise," we mean an internally experienced state of crowding and confusion created by a variety of stimuli, the quantity, intensity and unpredictability of which make it difficult for individuals so afflicted to tolerate and organize their experience. Attempts to do so may only add to confusion and psychotic phenomena.

Adrenergic beta-Antagonists↗
PubMed1986

Beta-blockers in the severely and profoundly mentally retarded.

The authors present data from four different institutions from open clinical trials of propranolol in 19 mentally retarded patients with IQs less than 50. When customary forms of treatment had failed, propranolol was initiated. A table showing changes in the patients' behavior is included. Twelve patients demonstrated a pronounced improvement in self-abusive and aggressive behavior, four made moderate gains, and three were considered unchanged. The authors postulate that at least some aspects of the behavioral improvement were due to the peripheral anxiolytic action of the beta-blockers. Contrary to other reports of using higher doses (greater than 520 mg/day range), the authors used a mean dose of 120 mg/day and consider the duration of time spent on the medication as a crucial factor in its effectiveness.

Adrenergic beta-Antagonists↗
PubMed1985

Nadolol as a treatment for akathisia.

The authors present three cases of patients with neuroleptic-induced akathisia who were successfully treated with nadolol, a peripherally acting beta blocker. They discuss the potential implications of this finding.

Adult↗
PubMed1983

Use of propranolol for provoked and unprovoked episodes of rage.

The use of propranolol to treat unprovoked rage episodes in brain-damaged patients has recently been reported. The authors report three cases that indicate a role for its use in the treatment of overall aggressiveness in brain-damaged or mentally retarded patients.

Adult↗
PubMed1977

The relationship between extra- and intracellular lithium concentration in human red blood cells: an in vitro study.

Red blood cells (RBC's) from normal volunteers were incubated in vitro at four different extracellular lithium concentrations. Extracellular lithium concentration affected RBC lithium accumulation in several ways. As extracellular lithium concentration increased, the inter-individual variability of RBC lithium accumulation increased. Furthermore, the ratio of RBC lithium concentration to extracellular lithium concentration (lithium ratio) increased in relation to increasing extracellular lithium concentration. A lack of agreement among the authors of recent reports dealing with the significance of the lithium ratio as a psychobiological measure has been noted. It is suggested that this lack of agreement may be due, in part, to the study of patients with differing levels of extracellular lithium.

Cell Membrane Permeability↗
PubMed1976

Heart rate and blood pressure in black newborns and in white newborns.

Sixty-one full-term, appropriate-weight black newborns had higher heart rates, replicating a racial heart rate difference, but did not differ significantly in systolic blood pressure from 71 white newborns. Systolic blood pressure in the newborn is related both to the total number of feedings from birth and to the total fluid intake.

Black People↗