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Biomedical subjects

J J Pinot

Publications and source records attributed to J J Pinot.

At least 19 recordsLinked to original sources

Long-term results with the Palmaz stent in the superficial femoral artery.

PURPOSE: Femoral stenting has demonstrated inconsistent and often disappointing long-term results. To compare out experience, we retrospectively analyzed a series of patients who had Palmaz balloon-expandable stents placed exclusively for superficial femoral artery (SFA) lesions. METHODS: From January 1990 to November 1993, 39 patients were evaluated for claudication (79%) or critical ischemia in 42 limbs. The culprit lesions were confined to the SFA: 24 (57%) occlusions and 18 (43%) stenoses, including 3 restenotic lesions. Stenting was elective in 12 (29%) cases: the 3 restenoses and 9 chronic, calcified occlusions. The remaining stents were applied for postangioplasty residual stenosis or angioscopic findings of thrombogenic luminal irregularities. A total of 55 prostheses were successfully implanted. All patients were maintained on ticlopidine and followed by routine duplex scanning. Follow-up angiography was performed in 28 (72%) patients between 4 and 45 months. RESULTS: In the postprocedural period, two acute thromboses (4.8%) occurred within 48 hours in patients who had long occlusions and poor runoff; no other major complications were encountered, for a clinical success rate of 95%. Follow-up evaluation ranged from 4 months to 4 years with a mean of 25 months. The restenosis rate was 19% (34% in occlusions; 10% in stenotic lesions, p = NS). At 24 months, cumulative primary patency was 77% and secondary patency 89%. CONCLUSIONS: Palmaz stents performed will in the SFA, demonstrating a low acute thrombosis rate and good long-term patency. The incidence of restenosis is likely to be greater in occlusions than in stenoses.

Aged

Exploration of cervico-encephalic vessels using trans-brachial approach on outpatients.

Among the several methods used for the exploration of supra-aortic vessels, none is perfect. The intra-arterial digital subtraction angiography is a secure method. The transbrachial approach for this purpose is a safe and efficient technique. The possible risks at the level of humeral artery can be reduced by applying the method described in the text. We present our experience among 200 patients, using mostly the right brachial artery. The quality of image was good in 3/4 of cases. Humeral artery thrombosis occurred only once. Failure was almost nil. We also suggest preliminary heparinization to reduce the rate of hematoma formation.

Ambulatory Care

[Treatment of stenoses of the urethra. 2].

This is a comparative study in 183 patients of the treatment of urethral stenoses by two-stage urethroplasty, internal endoscopic urethrotomy and urethrotomy via the Olbert catheter. Urethroplasty (39 patients) was preferentially carried out in patients with moniliform stenosis greater than 2 cm long in the penile and penoscrotal urethra. There was no significant difference in the indications for the two forms of urethrotomy. Good results were obtained for the 3 techniques in about 80% of cases but there was significantly higher complication rate with surgical urethroplasty. The failure rate of the 3 techniques did not differ significantly. The cost of treatment, on the other hand, greatly differed depending on the technique. Surgical urethroplasty was 2.8 times more costly than internal endoscopic urethrotomy and 10.4 times more costly than Olbert catheter urethrotomy. Olbert catheter urethrothomy was 3.7 times cheaper than internal endoscopic urethrotomy.

Humans

[X-ray computed tomography in congenital and acquired anomalies of the inferior vena cava].

The inferior vena cava (IVC) is a retroperitoneal key organ whose location and integrity must be checked in every scan. Computerized tomography (CT) of IVC provides interesting diagnostic elements which are complementary to the angiographic study: congenital abnormalities, even if they scarcely occur, are nevertheless important to detect, in order to prevent any mistake in the interpretation of the scan. Acquired abnormalities, are frequent. Today CT seems to be the most accurate method of exploration of neoplastic involvement in primary IVC tumors or external compression by retroperitoneal fibrosis. It is a non traumatic method allowing the visualization of the head of a caval thrombus inprecisely defined by phlebo-cavography. To summarize, a good scanning knowledge of the IVC and its abnormalities appears necessary, either to prevent any mistaken interpretation or to specify a pathological element with regard to a vascular exploration.

Humans

[False subaortic aneurysm after surgery of calcified aortic stenosis. Apropos of a case treated successfully].

The authors report a case of false aneurysm of the posterior subaortic region of the left ventricle after a technically difficult surgical decalcification in a case of aortic stenosis. At reoperation, the surgeon used the femoral artery and both vena cavae for canulation. A direct approach of this "vascular" tumour, which was exterior to the great vessels, confirmed the diagnosis and enabled the localisation of the internal orifice inside the left ventricle. This was closed simply by suturing. No previous cases of this kind were found in the literature. This report underlines the necessity of taking the greatest care when decalcifying this region in order to avoid this type of serious complication.

Aorta, Thoracic

[Dilatation of the urethra by inflatable balloon catheter].

An inflatable balloon catheter of the Gruntzig type was used to dilate the urethra of 25 patients. The procedure involves atraumatic catheterization by a vascular catheter under televised urethroscopy, followed by introduction on a flexible guide of the balloon catheter which is then inflated. The stenosis is visible on the balloon and the rapidity with which it "yields" can readily be appreciated. Control of dilatation is effected by voiding urethrography. This method entails much less discomfort than conventional urethral dilatation. No complication was observed in this series. Stenosis recurred in 3 patients who subsequently underwent a second balloon dilatation.

Dilatation

Comparative study of electrophysiological and Holter monitoring data in estimating sinoatrial function. Significance of intrinsic heart rate in disclosing autonomic sinus node dysfunction.

To study the diagnostic possibilities and mechanisms involved in sinus node dysfunction (SND), 26 patients with sick sinus syndrome were evaluated by basic electrophysiological tests before and after autonomic blockade, and by Holter monitoring. Based on intrinsic heart rate (IHR), two groups, a normal and a pathologic one, were separated. With Holter recordings, significant differences were manifested in minimal heart rate during sleeping and also in sinus cycles averaged for 24 h between the two groups. In patients with pathological IHR (n = 9) abnormal intrinsic rhythmicity were verified by electrophysiological means, while we found positive ECGs referring to sinoatrial dysfunction during the first 24 h of rhythm recording. The group of normal IHR (n = 17) covers patients with intrinsic SND (intrinsic SA block, 3/17 patients) and patients (14/17) where the electrophysiologic properties of the pacemaker cells were normal: normal intrinsic recovery time, gradual return to the stable intrinsic sinus cycle length in the postpacing secondary cycles, biphasic postextrasystolic patterns with a well-estimated intrinsic sinoatrial conduction time. Repeated Holter recording (total 26 X 24 h) revealed severe bradycardia (2 cases), SA block (4 cases), SA arrest (2 cases), tachybradyarrhythmia (1 case). Electrophysiological studies have a low diagnostic value in autonomic SND; repeated rhythm monitoring is obviously the best complementary method for appreciating the role and significance of autonomic tone in sick sinus syndrome.

Adult