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Biomedical subjects

J J Perrenoud

Publications and source records attributed to J J Perrenoud.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Value of computer tomography compared to angiography and echocardiography in the diagnosis of intracardiac thromboses].

Until recently the only means of diagnosing intracardiac thromboses were angiography and M mode and 2D echocardiography. The aim of this study was to assess the value of CAT scanning in this field and to compare it with angiography and ultrasonography. Twenty intracardiac thromboses were studied in 19 patients by CAT scanning: 14 in the left ventricle, 2 in the right ventricle, and 4 in the left atrium, one patient having both left and right ventricular intracavitary thrombosis. M mode and 2D echocardiography and angiography were carried out whenever possible. Although for different practical reasons all patients did not undergo all three investigations, CAT scanning appeared to be the most reliable diagnostic method in intracardiac thrombosis, being more specific than either angiography and ultrasonography. In addition, the therapeutic effects of anticoagulant therapy on the thrombus can be assessed and other associated pathology such as aneurysm, pericardial reaction, dilatation of the cardiac cavities, myocardial and valvular calcification can also be demonstrated.

Adult↗
PubMed1982

Association of coarctation of the thoracic aorta with fibromuscular dysplasia of the renal arteries: a case report.

The case of a 25-year-old woman with coarctation of the thoracic aorta and combined bilateral fibromuscular dysplasia of the renal arteries is reported. Although marked hemodynamic changes induced by the coarctation were probably pre-existent, hypertension was revealed only during the last month of her first pregnancy and was spontaneously corrected 2 months post partum. Surgical treatment of the thoracic coarctation did not influence blood pressure which remained normal.

Adult↗
PubMed1982

[Value of echocardiography in the diagnosis of Uhl's disease. Apropos of a case in an adult].

Uhl's anomaly, or paper thin right ventricle is a rare congenital malformation which may present with variable degrees of hypoplasia. The most severe forms are encountered in infants and children, but a less serious form occurs in adolescents and adults which, clinically. There are a number of echocardiographic features common to both diseases but paper-thin right ventricle may be distinguished by the finding of premature opening of the pulmonary value. The increased atrial contraction in these patients with right ventricles of reduced compliance is directly transmitted to the pulmonary artery, leading to end diastolic opening of the pulmonary value before tricuspid closure. The case presented underlines the value of M mode echocardiography in the diagnosis of Uhl's anomaly and in the differential diagnosis with Ebstein's anomaly.

Diagnosis, Differential↗
PubMed1981

[Preoperative mechanical hemolysis in triple rheumatic valve disease. Apropos of 1 case].

A 25-year-old Senegalese woman with severe multivalvular disease presented with jaundice (unconjugated bilirubin) augmented by exertion without evidence of frank anemia. Following the exclusion of all other causes of hemolysis, the diagnosis of mechanical hemolysis secondary to deformed valves was established. The jaundice and laboratory evidence of hemolysis diminished markedly after placement of (Starr) aortic and mitral valve prostheses and a tricuspid commissurotomy. While chronic hemolysis due to ball or disc valve prostheses is usually clinically insignificant yet often described in the literature, hemolysis complicating non-operated valvulopathies is a rare clinical condition and, in contrast to the case presented, usually less severe than hemolysis following valve prosthesis insertion.

Adult↗
PubMed1981

[Value and limits of two-dimensional echocardiography in acquired cardiopathies in adults].

Two-dimensional echocardiography is complementary to the unidimensional technique. It offers the possibility of examining a wide area of the heart in real time and obtaining multiple cross-sectional views from several different chest wall transducer positions. Although generally quite accurate this new technique has some limitations, i.e. with regard to resolution of an ultrasonic image. Two-dimensional echocardiography is mainly useful for evaluation of left ventricular function and congenital heart diseases, and for diagnosis of left ventricular and auricular thrombi.

Adult↗
PubMed1981

Dissection of ascending aorta. Rare complication of aortocoronary venous bypass surgery.

Dissection of the ascending aorta is a rare complication of aortocoronary bypass surgery. A 63-year-old man who had received a double graft was found to have dissection of the ascending aorta, which was shown angiographically four months after operation. Since the patient was asymptomatic, operation was postponed. He has been followed up regularly and two years later his condition is still satisfactory.

Aortic Dissection↗
PubMed1981

Assessment of myocardial sympathetic activity in coronary heart disease.

We measured adrenaline, noradrenaline and dopamine beta-hydroxylase in arterial and in coronary sinus blood in 14 patients with coronary artery disease, at rest and under pacing-induced ischemia. Pacing increased the concentrations of adrenaline and noradrenaline in both arterial and coronary sinus blood. The origin of the adrenaline increase appears to be extramyocardial. The arteriovenous differences indicated that the heart extracts adrenaline and releases noradrenaline. These differences were not significantly changed by pacing, nor by the administration of propranolol. No marked changes in the concentrations of dopamine beta-hydroxylase were observed, except under pacing after propranolol, in which case a release from the heart occurred.

Adult↗
PubMed1981

[Value of transverse radiotomography in the control of the permeability of aortocoronary bypasses, compared with coronary angiography].

The object of this study was to determine whether transverse radiotomography, despite cardiac movement, could be used to visualise aortocoronary bypass grafts to confirm their patency or obstruction. The results were then compared with those of coronary angiography. 20 patients with a total of 38 grafts (18 on the left anterior descending, 8 on the circumflex and 12 on the right coronary artery) underwent tomography. 1 or 2 60 ml boluses of iodide contrast medium were injected into a fore arm vein and 3-5 films were exposed after each injection at 15 sec intervals. Coronary angiography was performed in 16 patients and the results of tomography were identical to those of coronary angiography : 23 patent and 6 occluded grafts. In one case, subtotal proximal stenosis of the left anterior descending artery allowed sufficient flow for the graft to be opacified and considered patent on tomography. The correlation between transverse radiotomography and coronary angiography was excellent. Transverse radiotomography, a non-invasive technique, is very useful in operated patients with atypical chest pain and in those with recurrent angina in whom obstruction of the graft is feared. It does not seem destined to replace control coronary angiography after bypass surgery, but it may be indicated is selected cases.

Adult↗
PubMed1980

[The value and advantage of computer assisted tomography as compared to angiography in evaluating patency of aorto-coronary grafts].

Sixteen patients with 31 aorto-coronary grafts have been studied by CT and by coronary arteriography to compare the results of the two methods in the evaluation of graft patency or occlusion. Correlation of the two technics is excellent (100%). However, graft stenoses are not visualized on CT in its present state of technical performance and are the limiting factor for this noninvasive procedure. In patients with precordial pain and aorto-coronary grafts, CT should be done first to evaluate graft patency and only be checked by coronary arteriography if there is disagreement between the CT result and clinical assessment of the case.

Coronary Angiography↗
PubMed1980

[Utilization of anti-arrhythmic drugs].

Wise utilization of antiarrhythmic drugs depends on a profound knowledge of their intracellular effects; however, due to widely varying individual response to such drugs, long clinical experience and a certain degree of empiricism are usually necessary. In view of the negatively inotropic effect of the majority of the antiarrhythmic drugs and the potential danger of their association, it seems advisable to recommend that benign arrhythmias should not be treated. Finally, a thorough understanding of the mechanism of complex arrhythmias is essential in selecting the appropriate medical treatment.

Action Potentials↗
PubMed1980

[Pseudo Q waves in myocardial necrosis: a pitfall with a Wolff-Parkinson-White appearance].

The diagnosis of inferior myocardial infarction was wrongly made in a patient with a history of chest pain and Q waves in Leads 3 and aVF. Despite a normal PR interval, ventricular preexcitation was suspected on the deformation of the upstroke of the QRS complex, suggestive of a delta wave. Ventricular and coronary angiography and exercise Thallium 201 myocardial scintigraphy allowed the diagnosis of myocardial infarction to be eliminated. Endocavitary electrophysiological recordings confirmed the presence of an accessory atrioventricular conduction pathway (Kent bundle) and explained the intermittent appearances of the WPW syndrome on ECG. The patient was investigated after the acute episode, and the absence of cardiac enzyme estimations at that time made the rectification of the diagnosis more difficult.

Adult↗
PubMed1978

[An enigmatic member of the family of Scrofulariaceae: Digitalis].

Digitalis still remains a source of astonishment to electrophysiologists as well as clinicians. The presently known effects on the neurovegetative system and the action potential are described, and some clinical problems which may lead to ineffective digitalization or digitalis intoxication are stressed. Clinical and ECG manifestations and some therapeutic aspects are pointed out.

Digitalis Glycosides↗
PubMed1978

[Disseminated intravascular coagulation with microangiopathic hemolytic anemia and bone necrosis associated with a prostatic microcarcinoma].

Presentation of a case of disseminated intravascular coagulation with micro-angiopathic hemolytic anemia, associated with a micro-carcinoma of the prostate. In the absence of other etiology it is postulated that the carcinoma was responsible for the hematological disturbance in spite of its small size andlack of either metastases or mucin secretion. The unusual discovery in this disease of bony necroses of the vertebrae, which are attributed to ischemia following micro-thromboses, is also discussed.

Adenocarcinoma↗
PubMed1978

[A case of pseudo-tumoral lymphoid hyperplasia or Castleman's disease].

The relatively rare pseudotumoral lymphoid hyperplasia (benigh lymphoid or reactive lymphoreticular hyperplasia; pseudolymphoma; Castleman's disease) arises from the lymph nodes, usually in the mediastinum. The disease assumes tow histologically and clinically different forms: the first, angiofollicular, is often symptomless, while the second, lymphoplasmocytic, is sometimes associated with a marked chronic inflammatory syndrome. The etiology is unknown, but is probably a reaction of the lymphoplasmocytic system to an antigen, possibly of viral origin. Diagnosis is based on histology. Surgical treatment is curative. A rare form of this unusual disease is reported with reference to the morphological differential diagnosis; the similarities with immunoblastic lymphadenopathy are emphasized.

Adult↗