Measurement and monitoring of acutely ill patients by digital computer.
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Biomedical subjects
Publications and source records attributed to J J Osborn.
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A variable-orifice pneumotachograph is described. It has a resistance that is relatively constant over a flow range from 0.1 to 2.5 liter/sec so it puts out a differential pressure signal that is directly proportional to flow. It is specifically designed for monitoring respirator patients and sacrifices some of the accuracy of a laminar flow (Fleisch) type device to gain greatly improved immunity to artefacts caused by airway water.
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Clinical decisionmaking depends upon properly interpreting the significance of physiological and other clinical data. Our experience, summarized in six case studies, suggests that no one variable is sufficient for making clinical decisions. Rather, different parameters are relevant in different situations. This article summarizes two techniques for improving the effectiveness of clinical decisionmaking in the ICU using quantitative physiological monitoring data. First, mathematical modeling has been used for measuring the volume of gas in the lungs of patients receiving mechanical ventilation. The technique analyzes the transient response to oxygen change; thus it is suitable for routine use in the ICU. Second, symbolic processing has been used for interpreting the clinical significance of measured data. This symbolic processing is used for recognizing artifact in measured data, determining expected physiological meaning of measured data in different clinical situations, identifying physiological status, and identifying therapy that may be appropriate for meeting therapeutic goals or correcting physiological problems in patients in the intensive care unit.
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Respiratory monitoring using airway measurements of flow, pressure, and oxygen and carbon dioxide concentrations is practical and useful for intensive care patients on respirator support. End-tidal PCO2 minute and tidal volumes, and compliance are the most useful simple measurements. On-line plots of pressure against volume and flow against volume are helpful in early detection of difficulty. More sophisticated pulmonary function tests such as maximum flows and volumes, functional residual capacity, and measurement of fast space and slow space can be easily automated under computer control. Respiratory monitoring provides painless, nonpenetrating measurements which are immediately available, and which reduce the incidence of undetected life-threatening respiratory accidents.