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J J Huart

Publications and source records attributed to J J Huart.

69 records · Page 4Linked to original sources
PubMedDate not supplied

[Serological markers of hepatitis B virus in hospitalized patients (Gastroenterology and Internal Medicine Service of the University Hospital Center of Brazzaville - Congo )].

The prevalence of serum markers of the hepatitis B virus was studied in 139 patients, 88 men and 51 women, at the Gastroenterology and Internal Medicine Department at the University Hospital in Brazzaville (Congo). The findings show that 125 individuals (89%), 79 men and 46 women, show signs of infection. Only 14 patients, 9 men and 5 women, show no hepatitis B virus markers. 64 individuals (46%) are carriers of Ag HBS, and among these, 23 (35.9%) are carriers of Ag HBe. Ac anti HBC was found 116 times (83.4%): 12 times by itself, and 16 times in association with Ac anti HBS. 43 individuals (30.9 %) are carriers of Ac anti HBS. Such high frequency of Ac anti HBS, whether or not accompanied by Ac anti HBC, argues in favor of the age of the infection. The study points out the high frequency of hepatitis B virus markers (89.8 %) compared with blood donors (7 to 9 %). This should incite government officials to set up some preventive procedures.

Adolescent↗
PubMedDate not supplied

[Therapy of bacterial infections occuring during aplastic phasis of acute leukemias (author's transl)].

On a three years' period, 122 patients with AL (45 children, 76 adults) received 158 treatments of induction, involving a severe medullary aplasia. In 48 cases (30.4%) none infectious complication was recorded. In the other 110 observations, infections syndrome (septicemia due to gram-negative rods above all) was treated by an early and intensive combination antibiotherapy (three successive protocols are employed, after failure of the precedent), in association with a careful medical reanimation and trasfusions of granulocytes in 16 cases. Regression was obtained in 94 cases (59,5%) but infection was lethal in 16 patients (10.1%). More than cytological variety of AL, principal pronostic element is age (15 deaths among 88 infections episodes in adults, one among 22 in children). Granulocytes rate at the time of aplasia (lower than 500 /mm3) also represents a factor of gravity. Among 94 infections episodes, antibiotherapy was successful alone in 81 cases (86.2%), illustrating the fundamental place of this treatment.

Acute Disease↗
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[Blood transfusion].

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Blood Group Antigens↗
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[Contribution of ABVD chemotherapy in refractory Hodgkin's disease. Study of 21 observations (author's transl)].

On a two years period, 21 patients with advanced Hodgkin's disease who failed usual therapeutic proceedings were treated by a sequential combination chemotherapy with adriamycin, bleomycin, vinblastine and dacarbazine (ABVD, first described by Bonadonna). Initially 16 patients among 21 had a disseminated disease with stage III B (9 obs.) or IV B (7 obs.). Previously all had been submitted, during a four years mean period, to multiple therapeutic trials always involving MOPP plus lymphoid irradiation and/or other combination chemotherapy. In 19 patients among 21, ABVD was decided because of persistent abdominal lymphoid and/or visceral localizations (liver: 6 obs.; lung: 4 9bs; épidural space: 1 obs.). In 12 patients, abdominal localizations were proved after delayed staging laparotomy. Immediate results with ABVD were: CR: 9 obs. (43%); PR: 5 obs. (24%); failure: 7 obs. (33%). With vinblastine interrupted by intermittent ABVD, 4 CR are persisting with a 8 to 23 months' follow up; among 5 patients who relapsed (3 to 24 months), 4 are still alive. After irradiation of résidual lesions, 4 PR among 5 are persisting with a 6 to 12 months' follow up. For the 21 patients, median survival has not been reached at 30 months.

Adolescent↗