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Biomedical subjects

J J Haggerty

Publications and source records attributed to J J Haggerty.

32 records · Page 2Linked to original sources
PubMed1986

Appearance of mania in drug-resistant bipolar depressed patients after treatment with L-triiodothyronine.

L-Triiodothyronine (T3) has been reported to potentiate the antidepressant effects of tricyclic antidepressants (TCAs) in patients who do not respond to these drugs, while thyroxine (T4) has been used to treat rapid-cycling bipolar disorder patients. The development of mania in antidepressant-resistant bipolar depressed patients after T3 was added to their antidepressant treatment is reported. It is speculated that thyroid hormone-catecholamine receptor interaction might underlie these T3-associated clinical manifestations. It is concluded that T3 did not prevent the switch to mania in the bipolar depressed patients reported here. Further study is necessary to determine if T3 plays a role in promoting the switch to mania in depressed patients treated with T3 in conjunction with TCAs, and if bipolar depressed patients are particularly vulnerable to mania from the combined effects of TCAs and T3.

Adult↗
PubMed1985

Life adaptation after percutaneous transluminal coronary angioplasty and coronary artery bypass grafting.

Life adaptation of 32 patients who had undergone percutaneous transluminal coronary angioplasty (PTCA) for coronary stenosis was compared with that of 15 patients who had coronary artery bypass grafting (CABG). Patients were matched for psychosocial, anatomic and cardiac functions. Life adaptation was measured at 6 and 15 months after PTCA or CABG by the Psychosocial Adjustment to Illness Scale (PAIS), a multidimensional instrument that evaluates change in 7 primary life domains. The overall PAIS scores for patients who had undergone PTCA were significantly better (p less than 0.04) than the scores for those who had undergone CABG after 6 months, and this superior functioning continued after 15 months (p less than 0.05). After 6 months patients who had undergone PTCA functioned better at work (p less than 0.005), in sexual performance (p less than 0.0001) and with their families (p less than 0.002). The improvement in work functioning continued at 15 months (p less than 0.04), but the differences in sexual and family domains became nonsignificant.

Adaptation, Psychological↗
PubMed1985

Antithyroid antibodies in depressed patients.

The presence of antithyroid (antimicrosomal and antithyroglobulin) antibodies was assessed in 45 psychiatric inpatients with prominent depressive symptoms (28 with DSM-III major depression). Nine patients (20%) had detectable titers of antithyroid antibodies, a rate considerably higher than the 5%-10% observed in the normal population. Each of these nine patients with symptomless autoimmune thyroiditis had normal baseline serum thyrotropin concentrations and normal thyroid function (as assessed by T4, T3 uptake, and free thyroxine index). These findings support the hypothesis of subtle thyroid dysfunction in a sizable sample of psychiatric inpatients with prominent depressive symptoms.

Adolescent↗
PubMed1985

Mania following change from trazodone to imipramine.

Case reports are presented of two depressed patients with probable bipolar disorder who did not respond to trazodone but developed mania when this drug was abruptly replaced with imipramine. Clinical and theoretical implications are discussed.

Adult↗
PubMed1984

Long-term psychotherapy of Munchausen syndrome.

In this paper we describe the long-term outpatient psychotherapy of a patient with Munchausen syndrome. We present detailed observations on the role of current object relations in the evolution of factitious symptoms, and discuss the communicative aspects of this behavior.

Adult↗
PubMed1982

Strongyloidiasis presenting as depression: a case report.

A case is described in which an occult parasitic infection. Strongyloidiasis, presented with symptoms suggestive of hypochondriacal depression. The diagnosis had been missed in several extensive medical evaluation and was made belatedly by stool specimen following unsuccessful treatment with antidepressant medication. Clinical features of this common infection are reviewed.

Aged↗
PubMedDate not supplied

Treatment of depression in cancer patients is associated with better life adaptation: a pilot study.

Major depression occurs in a significant number of cancer patients, and there is evidence that cancer patients with depression do not receive adequate antidepressant treatment. In an uncontrolled pilot study, the authors assess the degree of depression and the quality of life after the initiation of antidepressant medication treatment in 12 depressed cancer patients who received adequate antidepressant drugs and in 10 depressed cancer patients who received inadequate antidepressant treatment. These preliminary findings suggest that cancer patients with major depression benefit from antidepressant medication treatment and may experience an improved psychosocial adjustment to cancer. Controlled clinical trials will be necessary to verify these preliminary findings.

Adaptation, Psychological↗
PubMedDate not supplied

Behavioral medicine rounds: using a biopsychosocial approach for inpatient teaching.

The inpatient setting is commonly used to teach residents various aspects of the practice of medicine. This paper describes how inpatient teaching rounds can be expanded to teach the biopsychosocial approach to patient care. The background and early development, the structure of the teaching, and specific case examples of behavioral medicine rounds are described.

Adolescent↗