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Biomedical subjects

J J David

Publications and source records attributed to J J David.

At least 37 records · Page 2Linked to original sources

Oral sodium chloride in the management of schizophrenic patients with self-induced water intoxication.

Hyponatremia is always present in patients with water intoxication and accounts for many of the life-threatening symptoms and signs found in this population. In schizophrenic patients, water restriction, a cornerstone in the treatment of water intoxication, may be impossible to implement over the course of long-term management. The use of oral sodium chloride administration in such patients and its short-term efficacy in preventing major motor seizures are described.

Administration, Oral↗

Evaluation of patients with self-induced water intoxication and schizophrenic disorders (SIWIS).

The complications of water intoxication are well documented in the medical literature. Less well appreciated is the frequent appearance of self-induced water intoxication in patients with schizophrenic disorders. Six such patients are described and compared with the findings in the literature. Nonedematous, nonhypovolemic hyponatremia is the invariable biochemical abnormality in this syndrome and its multiple causes are discussed, including the syndrome of inappropriate antidiuresis. Severe hyposthenuria (urinary specific gravity 1.003 or less) is the silent biological marker that always antedates the complications of self-induced water intoxication and schizophrenic disorders (SIWIS). While recognizing that all patients with polydipsia do not go on to develop water intoxication, this biological marker provides the means to detect patients who may be destined to develop SIWIS; early recognition may prevent the major complications of this syndrome.

Adult↗

[Malignant syndrome in burned children. Nosologic and therapeutic approach].

A malignant syndrome was observed in 7 children less than 3 years old; the extent of burn was between 5 and 25 p. cent. This syndrome appeared between the second and the fifth days. It was characterized by fever, autonomic disorders and finally coma. The clinical, biological and anatomical features look like the syndrome of Reye. The use of dopamine before coma allowed healing.

Age Factors↗