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J J Adnet

Publications and source records attributed to J J Adnet.

126 records · Page 7Linked to original sources
PubMedDate not supplied

[Osteoblastoma of the 1st metatarsal bone. Apropos of a case].

Metatarsal localisation of osteoblastoma is rare. We report a case of a sixteen years old girl. The foot was swollen but unpainful. The plain film showed an extensive, osteolytic tumor of the whole of the first metatarsal bone. The radiological diagnosis could be discussed with an aneurysmal cyst, a chondroma, a desmoplastic fibroma, a fibrous dysplasia, an angioma. The total resection was possible without opening of the tumor and reconstruction was possible with a tibial graft. The pathological diagnosis was benign osteoblastoma. Recovery was uneventful.

Adolescent↗
PubMedDate not supplied

[Ultrastructural diagnostic problems of pleural tumors. A study of 125 cases (author's transl)].

Ultrastructural studies may improve the diagnosis of pleural tumors. A comparative study of 125 primary and secondary pleural cancers provided the major structural features needed for differential diagnosis. Two cell types were always present in malignant mesothelioma: differentiated mesothelial, and fibroblastoid cells. The former had some features of metastatic epitheliomas (microvilli, microfilaments, junctional complexes, basement membranes). The later were specific. They were sometimes isolated, had the general aspect of fibroblasts but possessed typical microvilli. It was difficult to assess the diagnosis of malignant mesothelioma on isolated differentiated mesothelial cells in pleural fluids or biopsies. Cilia or secretory granules were found only in metastatic cells. The finding of fibroblastoid cells in a pleural tumor proves its mesothelial origin.

Basement Membrane↗
PubMedDate not supplied

Modification of fibronectin distribution pattern in solid human tumours.

Using indirect immunofluorescence, the distribution pattern of fibronectin has been studied in a variety of solid human tumours and corresponding normal tissues. Fibronectin could be detected on normal epithelial cell membranes, in periglandular and perivascular basement membranes and in the intercellular stroma. No modification of this distribution pattern was detected in a variety of benign tumours or in certain pathological, non-malignant disorders (Dupuytren's contracture). In infiltrating mammary carcinomas, cell membrane staining disappeared even before invasion, the staining pattern of the glandular basement membranes became patchy, discontinuous and finally disappeared with invasion. Fibronectin persisted on vascular basement membranes and in the fibrous matrix remaining between the areas of infiltration. Similar modified fibronectin patterns were observed in bronchial, endometrial, prostatic, urinary bladder and thyroid carcinomas. In sarcomas, fibronectin disappeared from the membranes of transformed cells and decreased in intensity in the intercellular matrix. It can be stated, therefore, that the progressive loss of cell membrane and glandular basement membrane bound fibronectin is a characteristic feature of malignant human tumours and may assist with the histological differential diagnosis of atypical lesions and early invasion.

Basement Membrane↗
PubMedDate not supplied

[Evolution of the practice of sperm cryopreservation and fate of the preserved specimens : retrospective study of testicular cancer].

Testis cancer, chemotherapy and radiation can induce temporary or permanent infertility in men. Cryopreservation of spermatozoa seems an absolute prerequisite in such situation for male patients who are old enough to procreate. We propose a national retrospective study carried out in 17 CECOS. This survey demonstrates a regular increase for semen preservation in testis cancer and analyses the modalities of gametes preservation and their possible use. In view of this activity, we propose a discussion of the attitude of the various CECOS and of particular cases involving ethical issues.

Adolescent↗