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Biomedical subjects

J Igari

Publications and source records attributed to J Igari.

At least 163 records · Page 9Linked to original sources
PubMed1978

[Clinical and bacteriological studies on infections due to Acinetobacter calco aceticus (author's transl)].

The present studies concern with clinical backgrounds of the patients from whom Ac. calcoaceticus was isolated at the Juntendo University Hospital from Oct. 1976 until May 1977, and in-vitro observations on the susceptibility to antibiotics and chemotherapeutic agents of the organisms isolated from various clinical specimens from Sept. 1976 to May 1977. One hundred and eight strains of Ac. calcoaceticus were isolated from various clinical specimens of 78 patients. Approximately 70% of them was isolated from respiratory tract, and 6 approximately 8% from urinary tract, wound or bile. Ninety six of 108 strains were isolated in combination with other organisms. In retrospective view of 35 patients, all of them had one or more underlying diseases or predisposing factors, e.g., chronic disease, malignancy, infection due to other organism, surgery. Antibiotics had been administrated to 26 patients before onset of their infection with Ac. calcoaceticus. According to in-vitro susceptibility testing, the most active antimicrobial agents were minocyline and doxycycline. Gentamicin, tetracycline, kanamycin, amikacin, dibekacin, colistin, erythromycin, naladixic acid were given in this order. Most strains were resistant to ampicillin, sulbenicillin, cephaloridine, cefazokin, chloramphenicol, lincomycin, clindamycin, pipemidic acid and piperamic acid.

Acinetobacter↗
PubMed1977

[Clinical and bacteriological study on Flavobacterium meningosepticum (author's transl)].

The present study concerns in vitro observations on the susceptibility to antibiotics and chemotherapeutic agents of the strains of F. meningosepticum isolated from various clinical specimens at the Clinical Laboratory of Juntendo University Hospital and the assessment of their clinical significance of the patient, when they are isolated from clinical specimens. 1) Fifty-two % of the strains was isolated from sputum, 20% from urine and 8% from pus and exudate. Only 2 strains were obtained from blood and one strain from cerebro-spinal fluid. 2) The patients with F. meningosepticum from sputum had respiratory distress due to the basic disorder of central nervous system, respiratory system or cardiovascular system. An endotracheal tube or a tracheal canule was placed in most of the patients to assure a patient airway, and they received massive antibiotic therapy. Most of the patients with infected urine had functional and structural abnormality of the urinary tract, as well as a history of instrumentation, and had previously received antibiotic therapy. The bacteremia due to F. meningosepticum occurred after major operation in 2 patients, and one of them suffered from hydrocephalus associated with meningitis, moreover, in whom the organism was isolated from cerebro-spinal fluid. The route of infection with F. meningosepticum cannot be assessed certainly, but the correlation with catheterization or canulation strongly suggests that the instrumentation is required for the organism to become established. 3) In vitro test for sensitivity to 19 chemotherapeutic agents were done with the strains of F. meningosepticum isolated at the laboratory from August 1974 through July 1976. A large number of the strains were highly resistant to SB-PC, CB-PC, DKB, LCM, CL and NF, and resistant to AB-PC, CEZ and AMK. All strains were highly sensitive to MINO, DOTC and CLDM in this order, and were sensitive to EM, PA and NA. The relative sensitivity was found to TC, CP, GM and PPA.

Adult↗