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Biomedical subjects

J I Lopez

Publications and source records attributed to J I Lopez.

52 records · Page 3Linked to original sources

Xanthogranulomatous cholecystitis associated with gallbladder adenocarcinoma. A clinicopathological study of 5 cases.

The simultaneous presence of xanthogranulomatous cholecystitis and adenocarcinoma of the gallbladder has rarely been reported. A review of 53 cases of gallbladder adenocarcinoma in a 15-year period revealed 5 cases in which a concomitant diffuse xanthogranulomatous disease was observed. Clinical and pathologic features of these cases are commented and the diagnostic importance stressed. Both inflammatory and neoplastic components were closely mixed in 3 cases, thus making a prompt diagnosis difficult. Etiologic factors implicated in the development of both entities are considered.

Adenocarcinoma↗

Kaposi's sarcoma of the penis as an initial urological manifestation of AIDS. A report of two cases.

Kaposi's sarcoma of the penis is an initial manifestation of AIDS and the practising urologist should be aware of this form of presentation. We report 2 young intravenous drug abusers with this tumor in the male genitourinary system. The clinical course is unfavorable; therefore prompt diagnosis and management, based on the early recognition of the lesion, must be achieved.

Acquired Immunodeficiency Syndrome↗

Metastasising carcinoma of the urinary bladder presenting as a retro-orbital mass. Case report.

A 61-year-old man presented with macroscopic haematuria. Infiltrating transitional cell carcinoma of the urinary bladder was diagnosed after transurethral resection, and he was treated first with three doses of cisplatinum (100 mg/m2 at three week intervals) and then by radical cystectomy. Eleven months later he complained of progressive diplopia, which was found on computed tomography to be caused by a retro-orbital metastatic mass. There was no evidence of a space occupying lesion in the brain or of other metastases. The patient died four weeks later and permission for necropsy was refused. Despite the fact that carcinoma of the urinary bladder rarely metastasis in this way, urologists should be aware that it can happen.

Carcinoma, Transitional Cell↗

Hydrops fetalis and congenital mesoblastic nephroma.

The autopsy finding of congenital mesoblastic nephroma in a stillborn hydropic fetus is reported. We discuss the pathogenetic relation of both entities and summarize the optimal therapeutic attitude to follow in order to prevent this misfortunate outcome.

Female↗

[Renal adenocarcinoma in adolescents].

A case of renal adenocarcinoma arising in a 18 year-old boy is reported. This is a rare entity in childhood and adolescence that displays a similar histology to the adult form. The recent literature on its clinical and pathological features is reviewed. We conclude that, despite its rarity, adenocarcinomas must be included in the differential diagnosis of solid renal masses in early life.

Adenocarcinoma↗

Bladder transitional cell carcinoma.

We present a case of urinary bladder carcinoma in a child aged 13 that followed a benign course. This confirms the idea that epithelial bladder cancer in children pursues, a much less aggressive behaviour than in the adult, possibly on the basis of its well-differentiated nature. Despite the rarity of the lesion, it should not be overlooked in the differential diagnosis of haematuria in children.

Adolescent↗

Pharyngeal adenocarcinoma with intestinal features.

A high grade adenocarcinoma arising primarily in the pharynx of a 67-year-old man is presented. A CT-scan revealed a tumour mass growing in the pharynx, largely affecting parapharyngeal soft tissues. Lymph node metastases were found at clinical presentation. Both morphological and immunohistochemical studies displayed similar features to those of intestinal origin. To our knowledge, no previous examples of such neoplasm have been reported at this site. Its possible histogenetical origin is discussed.

Adenocarcinoma↗

Inflammatory pseudotumor of the liver. Report of a case and literature review.

The radiologic and histologic features of an inflammatory pseudotumor of the liver in a 62-year-old man are presented. The lesion was coincidentally discovered during clinical work-up of an acute pancreatitis caused by choledocholithiasis. Malignancy was suspected in the light of the radiologic presentation. To our knowledge, only 23 cases of inflammatory pseudotumor of the liver have appeared in the international literature. Its etiology remains unknown, although reactive-inflammatory or infectious mechanisms have been suggested. The present case seemed to be associated with bile flow obstruction, as the mass partially regressed following cholecystectomy and Vaterian sphincterotomy. Therefore, a hypothetical obstructive pathogenetic mechanism is considered. We conclude that this tumor-like condition must be considered in the differential diagnosis of solid masses in the liver.

Acute Disease↗

Retentive shear strengths of various bonding attachment bases.

The purpose of this study was to determine whether any of the commercially available attachment bases had significantly better retentive properties. This was determined by their shear strengths after all were bonded to bovine incisors with Auto-Tach. The mean shear strengths of sixteen bases were statistically compared to each other at 24 hours and at 30 days. In addition, the data were converted to pounds per square inch to ascertain if the size of the base significantly influenced the mean shear strength. It was concluded that (1). one of the foil mesh bases tested for shear strength was significantly superior to the two other base designs (indents with undercuts and solid bases with perforations); (2). mechanical retention of the attachment bases to the adhesive was not significantly affected after being placed in distilled water at 37 degrees C. either for 24 hours or for 30 days; (3). smaller foil mesh bases could be used without sacrificing significant shear strength.

Adhesives↗