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Biomedical subjects

J I Lin

Publications and source records attributed to J I Lin.

24 records · Page 2Linked to original sources

Peutz-Jeghers polyposis with metastasizing duodenal carcinoma.

A case of Peutz-Jeghers polyposis associated with duodenal carcinoma but without cutaneous pigmentation was presented. Duodenal carcinoma is the most commonly associated neoplasm. The presence of vitiligo in this patient is coincidental. Of 14 reported cases of Peutz-Jeghers syndrome associated with intestinal carcinoma, in only two was the tumor shown to originate in the polyp. In our case, too, we believe the carcinoma developed independently.

Adenocarcinoma↗

Superficial spreading adenocarcinoma of appendix, cecum, and terminal ileum.

A case of superficial spreading adenocarcinoma involving terminal ileum, appendix and cecum is presented. The tumor might primarily arise from the proximal part of the appendix with extension to the cecum and terminal ileum, although multicentric origin of the tumor cannot be excluded. The mechanism underlying superficial infiltration of the tumor is through close contact and intramucosal lymphatic spread.

Adenocarcinoma↗

Case report. Pulmonary dirofilariasis in man.

A case of pulmonary dirofilariasis in a 69-year-old woman is presented. A review of the literature revealed 56 documented cases. As in most cases of pulmonary dirofilariasis, our patient presented roentgenologically a single noncalcified coin lesion and required thoracotomy for diagnosis. The gross and histologic characteristics of the lesion, the life cycle of the parasite, the subcutaneous form of human dirofilariasis, and the possible role of the immunologic tests in establishing the diagnosis are briefly discussed. The incidence of pulmonary dirofilariasis appears to be increasing. Awareness that such entity exists is important since correct preoperative diagnosis can alleviate unnecessary surgical intervention.

Aged↗

CK-MB isoenzyme in patients with polymyositis.

Total serum creatine kinase and isoenzyme levels were studied in five patients with polymyositis. In all five patients, CK-MB isoenzyme was demonstrated by the column chromatography and electrophoretic method, although there was no evidence of myocardial infarction. The persistent elevation of CK-MB in patients with polymyositis is in contrast to the usual transient increase in myocardial infarction. Serial CK-MB isoenzyme quantitation can be used to distinguish myocardial infarction from polymyositis. CK-MB is a more sensitive indicator than AST and LDH as a monitoring device, but offers no advantage over total CK activity.

Adolescent↗

Angioimmunoblastic lymphadenopathy in a patient taking diphenylhydantoin.

The premise that chronic antigenic stimulation may be involved in lymphoproliferative disorders was considered in a patient with angioimmunoblastic lymphadenopathy who had received diphenylhydantoin (DPH) for seizure. This patient had clinical features overlapping with systemic lupus erythematosus (SLE) and serum antibody directed against DPH. It was proposed that the syndrome was caused by chronic antigenic stimulation with DPH.

Aged↗

Budd-Chiari syndrome in women taking oral contraceptives.

The report concerns a 21-year-old woman who, after having taken oral contraceptives for three months, developed the Budd-Chiari syndrome as the results of a widespread chronic obliterative process involving the intrahepatic venous system. The diagnosis was established by liver biopsy. She was treated with supportive measures and completely recovered after 28 days of hospitalization. The literature is reviewed regarding the Budd-Chiari syndrome in women taking oral contraceptives and the clinical and pathological features seen in those reported patients are discussed.

Adult↗