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Biomedical subjects

J I Cawood

Publications and source records attributed to J I Cawood.

At least 19 recordsLinked to original sources

Vascularized iliac crest with internal oblique muscle for immediate reconstruction after maxillectomy.

The vascularized iliac crest graft with internal oblique muscle as a method of reconstruction after maxillectomy has been used routinely at the Regional Maxillofacial Unit in Liverpool since 1993. Twenty-four consecutive operations have now been done and this paper reports an audit of our experience. An analysis of case-notes was made retrospectively after checking theatre diaries and records. A detailed inspection of the case-notes was undertaken to ascertain the presenting diagnosis, the complications and the outcome in terms of recurrence and disease survival. The type of defect was recorded, as was whether it had been possible to rehabilitate the patient both dentally and facially. At the time of this study 9 patients (38%) had died of their disease leaving 15 surviving. In 13 cases full dental and facial rehabilitation had been achieved or patients were waiting for an implant-retained prosthesis. Donor site problems important enough to be recorded in the notes were minimal, one case of abdominal wall weakness was noted, which required no intervention. The vascularized iliac crest graft with internal oblique muscle offers a complete solution for reconstruction after maxillectomy, providing there has been no sacrifice of the overlying facial skin and oral sphincter. There is sufficient height and depth of bone to maintain a facial profile and the muscle epithelializes to provide an ideal oral and nasal lining. This flap provides a base to enable full dental and facial prosthetic rehabilitation with either implant-retained or conventional prostheses.

Abdominal Muscles↗

Prosthetic rehabilitation of the atrophic maxilla using pre-implant surgery and endosseous implants.

Pre-implant surgery was carried out in 20 patients with advanced atrophy of the edentulous maxilla, using autogenous bone grafts. Endosseous implants were placed after the initial healing period and these were used to retain removable overdentures. Patients were observed for up to 5 years with 15 of the 105 implants placed being lost and two remaining as sleepers. The resulting implant success rate was 84%. Three patients had to return to conventional dentures while the remaining 17 expressed a high degree of satisfaction with their implant retained prostheses. Pre-implant surgery successfully extends the scope for implant therapy by providing sufficient bone for implant placement. The survival rate of implants in these cases appears promising up to 3 years, although further data is required to confirm the effectiveness of this treatment in the long term. Implant retained overdentures are able to successfully restore both oral function and facial form. The rehabilitation of the atrophic, edentulous maxilla remains difficult and complex, even when using pre-implant surgery and implant retained prostheses.

Adult↗

Oral rehabilitation with endosteal implants and free flaps.

Current management of oral cancer following tumour resection includes reconstruction of the surgical defect with free vascularized flaps and rehabilitation of orofacial form and function with the aid of endosteal implants. The choice of flap for reconstruction influences the use of implants, and further hard- and soft-tissue surgery is frequently required to enhance the success of oral rehabilitation.

Bone Transplantation↗

Prosthetic management of the atrophic mandible using endosseous implants and overdentures: a six year review.

This paper presents the treatment results and experiences gained from a retrospective study of patients treated with the IMZ osseo-integrated implant system and mandibular overdentures. Patients experiencing problems wearing conventional dentures were assessed by the implant team and 65 cases were treated with 154 endosseous implants placed in the edentulous mandible. Two to four implants were placed in each case and in addition some patients have had augmentation of the mandible with hydroxyapatite. The definitive mandibular prostheses were supported by both implants and the residual ridges. A variety of retention systems were utilised, which included different types of bar and clip, stud attachments, and magnets. The patients have been followed up regularly and evaluated after periods of between one and six years. Six implants have failed over this time resulting in a success rate of over 96%. Most patients expressed a high degree of satisfaction with their new overdentures. There was, however, a considerable burden of maintenance care required for the patient group examined. The findings demonstrate that implant retained overdentures offer a highly effective means of oral rehabilitation for the atrophic mandible, restoring both oral function and facial form.

Adult↗

Mandibular reconstruction and rehabilitation in childhood.

The management of a case of osteosarcoma of the mandible in an 7-year-old girl is presented. A variety of reconstructive techniques were used following surgical ablation of the tumour, including the use of a revascularised free bone flap and osseointegrated endosseous implants.

Child↗

Reconstruction of the severely resorbed (Class VI) maxilla. A two-step procedure.

The medium-term results of 12 patients that underwent reconstruction of the severely resorbed maxilla are reported. The method described entails a two-step procedure including Le Fort I osteotomy and grafting of the floor of the sinus and nose with particulate bone and hydroxyapatite (HA). The implants were placed in a second procedure. A 5% failure rate was noted in those patients that were grafted with particulate bone mixed with HA.

Adult↗

The functional case for miniplates in maxillofacial surgery.

A review is presented of the application of miniplates in maxillofacial surgery, with an emphasis on maxillofacial trauma. The advantages are highlighted, particularly in relation to functional considerations, including jaw function, weight loss, and pulmonary function. Miniplates are considered to be the best treatment for patients with maxillofacial fractures.

Bone Plates↗

Endosseous implants in the irradiated composite radial forearm free flap.

This paper describes the application of endosseous titanium implants that have been inserted into the vascularized bone of the radial forearm composite flap, used for mandibular reconstruction. The technique described allows full orofacial rehabilitation to be achieved, following ablative surgery and adjuvant radiotherapy.

Bone Transplantation↗

Anterior maxillary osteoplasty to broaden the narrow maxillary ridge.

The application of endosseous implants has extended the range of options and effectiveness of reconstructive preprosthetic surgery. Placement of endosseous implants in the edentulous maxilla is often restricted due to lack of available bone. Exposure of the underlying anterior maxillary bone frequently reveals a ridge form which is adequate in height but too narrow to accommodate endosseous implants. A horseshoe type osteotomy extending from the ridge crest into the floor of nose has been developed which allows advancement of the outer cortex to restore lost facial form and placement of an interpositional bone graft and endosseous implants to restore lost function.

Adolescent↗

Reconstructive preprosthetic surgery. I. Anatomical considerations.

When considering preprosthetic surgery of the edentulous jaws, it is important that the clinician fully understands the anatomical consequences of reduction of the residual ridges. Based on a classification of the edentulous jaws, changes in the relationship of the jaws to each other, in muscle relations and function, in the oral mucosa and in facial morphology have been measured relative to the stage of resorption of the edentulous jaws.

Humans↗

Monitoring of Tübingen endosseous dental implants by glycosaminoglycans analysis of gingival crevicular fluid.

Glycosaminoglycans (GAG) in gingival crevicular fluid (GCF) samples were determined by cellulose acetate electrophoresis and densitometric scanning. Two GAG bands, hyaluronic acid and chondroitin-4-sulphate (C4S), were detected in GCF from implants, similar to the profile from teeth. High GCF volumes and GAG contents, notably C4S, may reflect postoperative alveolar bone responses, particularly resorption, at different stages of healing and function of successful implants. They may also indicate adverse tissue changes in failing implants. A comparison of crowned implants and matched teeth suggests that the periodontal ligament contributes to the GCF GAG profile. This may be a useful laboratory method of monitoring implants to detect adverse tissue responses at an early stage.

Adolescent↗

Effect of intermaxillary fixation on pulmonary function.

A study to measure the pulmonary effects of intermaxillary fixation (IMF) demonstrated that this technique produces a significant degree of airway obstruction. This may be dangerous to patients with limited respiratory reserve due to chronic obstructive airways disease. The impairment of pulmonary function can be assessed pre-operatively and should be estimated in high risk patients. Alternative management of stabilization of jaw fractures that avoid IMF should be considered in such patients.

Airway Obstruction↗

Facial trauma.

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Facial Bones↗

Salivary gland scintigraphy--a suitable substitute for sialography?

By comparing 27 patients who had both scintigraphy and sialography in the assessment of salivary gland disease, scintigraphy has been shown to correlate well with abnormal sialograms. It is suggested that scintigraphy could become the initial screening procedure in the assessment of salivary gland disease. A normal scintiscan is unlikely to miss significant pathology (as demonstrated by sialography), but sialography must always be performed if there is a suspicion of duct obstruction on scintigraphy. Patients suspected of focal salivary gland pathology such as tumour have not been investigated. The series documents the findings in patients who presented with facial pain, swelling or xerostomia suggesting sialadenitis, duct occlusion or Sjögren's syndrome.

Adolescent↗

The immediate or delayed replacement of teeth by permucosal intra-osseous implants: the Tübingen implant system. Part 2: Surgical and restorative techniques.

The previous paper emphasised the importance of case selection in determining success in the use of the Tübingen implant system. Adherence to strict clinical techniques has an equally important influence on implant success and failure. This paper describes the surgical and restorative techniques involved in the use of the Tübingen implant and comments on the authors' initial experiences with this system.

Aluminum Oxide↗