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Biomedical subjects

J Husband

Publications and source records attributed to J Husband.

28 records · Page 2Linked to original sources
PubMed1980

Diagnostic techniques: their strengths and weaknesses.

The diagnostic techniques available for estimating tumour volume in patients are reviewed, using tumours in the lungs and lymph nodes to illustrate the advantages and disadvantages. Tumour growth in lymph nodes is very difficult to assess using lymphography but useful information has been obtained in highly selected patients. The introduction of ultrasound and CT have provided a method of assessing tumour size once it has broken out beyond the confines of the node. In general, CT appears to be the most accurate method of estimating tumour regression and growth of abdominal tumour at the present time. Physical imaging techniques have been used in various other sites for estimating tumour volume but the main advantages and disadvantages of conventional radiology, ultrasound and CT have been illustrated. Isotope scanning and thermography have not been widely used to quantify tumour volume because other techniques provide better delineation of the tumour margin which is the most important factor. However, even the most accurate methods available today are still dependent on subjective visual assessment.

Humans↗
PubMed1979

Computed tomography applied to radiotherapy treatment planning: techniques and results.

In order to assess the role of computed tomography (CT) in radiotherapy treatment planning, tumors were localized by conventional techniques and with CT using an EMI CT5005 scanner. CT scans were obtained under conditions simulating radiotherapy. A comparison between the two localizations was made, and detailed results are given. Forty-seven of 123 patients had their treatment plan altered, implying that, provided information is obtained and used correctly, CT can play a significant role in radiotherapy treatment planning.

Abdominal Neoplasms↗
PubMed1978

Comparative clinical impact of endoscopic pancreatography, grey-scale ultrasonography, and computed tomography (EMI scanning) in pancreatic disease: preliminary report.

Grey-scale ultrasound scanning (US), computed tomography (CT), and endoscopic retrograde cholangiopancreatography (ERCP) were performed in a series of 50 patients with known or suspected pancreatic disease. The impact of the individual tests were assessed in the relevant clinical context. With a maximum of 100, the overall clinical impact score of ERCP (75) exceeded that of CT(63) and US (36). In patients with obscure pain, and in those with relapsing pancreatitis, a combination of US and ERCP provides good clinical guidance. Computed tomography scanning can currently be reserved for documentation of patients with a major mass lesion. None of the techniques can detect early pancreatic cancer, except of the papilla of Vater, where ERCP is diagnostic. Recommendations for future diagnostic strategies may alter as grey-scale ultrasonography and computed tomography develop, and, in any case, depend on many factors including local expertise, availability, and cost.

Adolescent↗
PubMed1976

Cerebral ventricular size and cognitive impairment in chronic schizophrenia.

By comparison with age-matched controls in employment, 17 institutionalised schizophrenic patients were shown by computerised axial tomography of the brain to have increased cerebral ventricular size. Within the group of schizophrenic patients increased ventricular size was highly significantly related to indices of cognitive impairment.

Adult↗
PubMedDate not supplied

CT evaluation of the resectability of gastric cancer postchemotherapy.

BACKGROUND: To determine the accuracy of CT in the postchemotherapy assessment of resectability of gastric cancer. METHODS: Thirty patients deemed to have unresectable gastric cancer on CT were studied. This was verified at laparotomy in 10 of these patients. Following initial assessment, all received three to eight cycles of chemotherapy aiming for disease control and potential resection. Serial CT examinations, endoscopy, and biopsy were performed after the fourth, sixth, and eighth cycle of treatment. The primary tumor and lymph nodes seen on CT were compared with operative findings. RESULTS: After completion of chemotherapy, CT findings were correct in 23 patients. Fourteen of them had operable tumors and nine were inoperable. However, the CT findings were either equivocal or incorrect in the remaining seven patients. CONCLUSION: Chemotherapy is now able to downstage a previously inoperable gastric cancer, and CT is an accurate method in identifying those patients who can proceed to resection.

Adenocarcinoma↗