Giant-cell arteritis and hypothyroidism.
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Biomedical subjects
Publications and source records attributed to J How.
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100 patients showing a significant number of stomatocytes were identified from the microscopic examination of 4291 peripheral blood films. The distinctive red cell appearance was most commonly found in patients with neoplastic, cardiovascular or hepatobiliary disease including acute alcoholism and during therapy with certain drugs some of which are known to be stomatocytogenic in vitro.
Two patients with anorexia nervosa who developed progressive haemolytic anaemia during chlorpromazine therapy are presented. In each case, withdrawal of the drug alone led to a prompt haematological response. Drug-induced oxidant damage is proposed as being the underlying haemolytic mechanism.
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Explore the source record for details and available documents.
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