Search PubMed⌕ Search

Biomedical subjects

J Hornová

Publications and source records attributed to J Hornová.

At least 19 recordsLinked to original sources
PubMed2006

[Macular area in glaucoma patients].

PURPOSE: To evaluate the possible use of HRT II and OCT 3 for detection and monitoring of glaucoma changes in the macular area. METHODS: In the retrospective study 65 eyes (13 healthy and 52 with primary open angle glaucoma) of 36 patients have been monitored. All patients underwent complete ophthalmologic examination including visual acuity testing, biomicroscopy of fundus, computer perimetry, HRT II and eleven patients were examined using OCT 3. The visual field has been tested on HFA (Humphrey Field Analyzer) using the full threshold test 30-2. Foveolar sensitivity and foveolar sensitivity compared to the age have been evaluated. The optic nerve head has been examined and subsequently evaluated using HRT II. The retinal nerve fiber layer (t-RNFL) and Cup Shape Measurement (t-CSM) in the temporal area have been monitored. The macula has been examined on OCT 3. Foveolar thickness, inner and outer macular thickness, average macular thickness and aggregate macular volume have been monitored. RESULTS: Decrease of the visual acuity and foveolar sensitivity have been registered with the deterioration of the visual field. Further general decrease of the value of t-RNFL and increase of the t-CSM index have been registered from the results of the HRT II examinations. This corresponds to decrease of the nerve fibers and excavation deepening in the temporal area. Average macular thickness and total macular volume examined on OCT 3 demonstrate aggregate decrease of values with the progressive changes in the visual field. CONCLUSION: With the progressive visual field changes with the open angle glaucoma patients occurs also deterioration of finding in the macular area. Changes discovered using the subjective examination and expressed as a slight decrease of the visual acuity as well as decrease of the foveolar sensitivity on HFA can be objectively proved using HRT II and OCT 3.

Female↗
PubMed2003

[Clinical preoperative study and results of trabeculectomy after 2 years].

PURPOSE: To determine whether preoperative anatomical and functional results have an influence on the postoperative decrease in intraocular pressure (IOP) and therapy two years after trabeculectomy (TE). METHODS: In a retrospective study 40 patients (80 eyes) with primary open angle glaucoma were followed. They underwent TE with two releasable sutures on both eyes performed by the same method and the same surgeon. The preoperative and postoperative levels of IOP (as measured by the Goldmann tonometer) and therapy (according to target pressure) were compared with preoperative gonioscopy (Shaffer's scale 0-4), the excavation of the optic nerve (c/d ratio) and preoperative results of the visual field (threshold tests and Aulhorn's classification 0-V). RESULTS: The preoperative size of the angle of the anterior chamber has no expressive influence on the postoperative decrease in IOP (p = 0.079), there is an even smaller influence on decrease on therapy (p = 0.619). As well the preoperative excavation of the optic disc had no influence on the postoperative decrease in IOP (p = 0.179) and therapy (p = 0.467). There is an analogy with the visual fields; preoperative changes had no influence on the postoperative decreasee IOP (p = 0.502) and therapy (p = 0.247). CONCLUSION: Preoperative anatomical and functional status had no the influence on the success of TE.

Female↗
PubMed2002

[A pediatrician's views on the treatment of extensive hemangiomas in childhood].

Haemangiomas are the most frequent tumours of child age. They are found in 10-12% of infants. The authors summarize contemporary knowledge of the treatment of haemangiomas as well as their own experience with their treatment. They follow-up 18 children with haemangiomas at different sites, incl. ten with extensive haemangiomas. The latter were treated conservatively with prednisone and interferon alpha.

Angiogenesis Inhibitors↗
PubMed2002

[Long-term experience with glaucoma silicone implants in a multicenter study].

PURPOSE: To evaluate the experience with a glaucoma implant in complicated glaucoma, designed in collaboration with the Institute of Polymers in Prague. METHODS: In a multicentric retrospective study 91 eyes of 86 patients with otherwise uncontrollable glaucoma underwent GSI implantation in four departments. The implant of medical silicone consists of a tube with an internal diameter of 0.4 mm, connected to a round lens-shaped episcleral plate 169 mm2, covering the tube orifice from above. The indications were infantile glaucoma (14 eyes), traumatic glaucoma (14 eyes), various secondary glaucomas in 12, primary open-angle glaucoma in 11, neovascular and after PPV in 10 eyes each, usually after unsuccessful previous surgery. RESULTS: The average follow-up time was 20.5 months (SD +/- 19.5). Postoperative intraocular pressure at the last control was 6-22 mmHg in 56 eyes (50.95%). Life table analysis showed a cumulative probability of 494% (at least qualified success). Long-term hypotony was seen in 6 eyes. CONCLUSIONS: The GSI is comparable with similar tube shunts but is much less expensive. In vitro experiments are planned to improve the construction of the implant and its results.

Adolescent↗
PubMed2001

[Frequency of removal of releasable sutures after trabeculectomy].

PURPOSE: To find out the frequency and time of extraction of releasable sutures (RS) in the first and second operated eye. METHODS: In a retrospective study, 40 patients with primary open glaucoma were followed. Patients underwent trabeculectomy with two RS on both eyes. The trabeculectomy was performed by the same surgeon and by the identical method. RESULTS: It was not necessary to remove RS postoperatively in 30% of the first operated eyes and in 35% of the second operated eyes. One RS was removed in 37.5% of the first and 32.5% of the second eyes. Two RS were removed equally in 32.5% of both eyes. The differences of RS extraction on the first and on the second eye were not significant (p = 0.76). The extraction time was similar in both eyes, too. CONCLUSION: There is no difference between the first and second operated eye regarding the frequency and time of extraction RS.

Adolescent↗
PubMed2001

[Immediate and late intraocular pressure levels after trabeculectomy with releasable sutures] ].

PURPOSE: To evaluate the level of IOP and clinical status the first day after trabeculectomy (TE) with releasable sutures (RS), to follow up the extraction of RS in correlation with early and late postoperative level of IOP. METHODS: In a retrospective study, 40 patients with open angle glaucoma were followed. They underwent TE with two RS on both eyes. RESULTS: Hypotony (IOP less than 6 mmHg) was noted in 15 eyes (19%) the first day after the operation, shallow anterior chamber in 5 (6%). An IOP level higher than 20 mmHg was found in 11 eyes (13%) one day after surgery. No RS were extracted in the first group of 26 eyes. The early mean IOP was 10.15 +/- 7.1 mmHg the 1st day after surgery. IOP increased to a mean level of 15.3 +/- 3.8 mmHg two years after TE, 65% of eyes were without glaucoma therapy. One RS was extracted in the second group of 28 eyes. The early mean level of IOP was 10.7 +/- 6.5 mmHg, the late level 13.9 +/- 3.7 mmHg. The target pressure was maintained in 68% of the eyes without additional glaucoma therapy. The third group had 26 eyes and two RS were extracted after TE. The early mean level of IOP was 14.7 +/- 6.9 mmHg, the mean level of IOP was 15.8 +/- 3.9 mmHg two years after surgery, 39% of eyes were without glaucoma therapy. CONCLUSION: A level of IOP the first day after the operation, lower than 6 mmHg or higher than 20 mmHg, must not be an indicator for failure of the surgery. Observing the level of IOP 3-5 days after surgery determines whether the RS is to be removed or not. The use of RS prevents short-term complications and the extraction of RS during the postoperative period can positively influence the evaluation of filtration.

Female↗
PubMed2001

[Monitoring intraocular pressure and therapy after trabeculectomy in both eyes during a 2-year period].

PURPOSE: To evaluate the level of intraocular pressure (IOP) and glaucoma therapy during two years after trabeculectomy (TE) with two releasable sutures (RS) on the first and the second operated eye. METHODS: In a retrospective study, preoperative and postoperative IOP and glaucoma therapy in 40 patients with open angle glaucoma, were evaluated. Patients underwent standardized TE with two RS on both eyes performed by the same surgeon. The first (worse) eye was operated on an average of three years after the diagnosis of glaucoma, and after 8.2 +/- 6.9 months the second (better) eye was operated on. RESULTS: TE with RS significantly decreased the level of IOP (p < 0.0001) and therapy (p < 0.0001) during a two year follow up period. There was no significant difference in IOP (p = 0.226) and glaucoma therapy (p = 0.086) between the first and the second operated eye. IOP was stabilised within 2-3 months after surgery for most patients, however glaucoma therapy was added for some to keep the target pressure. After one year IOP and therapy were stable for all patients. CONCLUSION: There is no difference between the first-worse and the second-better operated eye regarding IOP and glaucoma therapy during a two year period.

Female↗
PubMed2000

[Refractive procedures--LASIK and intraocular pressure in myopic eyes].

PURPOSE: To evaluate the effect of central corneal thickness (CCT) on the measurement of intraocular pressure (IOP) in normal myopic eyes before and after LASIK refractive surgery. METHODS: To determine CCT (by ultrasonic pachymeter NIDEC) and IOP (by Goldmann tonometer) in 27 patients (48 myopic eyes from -4 to -14 D) before LASIK (on Chiron Technolas 117) and 3 months after LASIK surgery. RESULTS: Mean CCT before LASIK was 543.8 microns (480-612), 3 months after was 430.6 microns (371-511), the difference--113.2 microns (48-157) is highly significant (p < 0.0001). Similar significant is also the decrease of mean IOP 3 months after surgery--about 5.4 mmHg (p < 0.0001). After LASIK surgery decrease IOP is 4.8 mmHg/100 microns. CCT is an important factor for accuracy of the Goldmann measurement. Myopic eyes need more attention, especially after photorefractive surgery, when CCT is decreased and therefore Goldmann IOP measurement is permanently underestimated.

Adult↗
PubMed1999

[Pachymetry in patients with glaucoma].

UNLABELLED: Central corneal thickness (CCT) was measured in 328 eyes of 167 patients (50 men and 117 women, an average age was 62 years). CCT was determinated by ultrasonic pachymeter NIDEC, design UP-1000, at Eye Department of 3rd Medical Faculty of Prague. RESULTS: The mean CCT at glaucoma patients was 561 microns, in margins 490-650 microns. CCT for right eyes were 0.567 +/- 0.035 mm, for left eyes 0.569 +/- 0.037 mm. There were no influence by previous operations (cataract, trabeculectomy and combined operations). NTG had the lowest CCT values 551 microns, POAG had 569 microns and OHT the greates value, CCT is 588 microns. CCT in patients with NTG was significantly lower (p = 0.047) than in POAG. The higher difference is between NTG a OHT (p = 0.015). We had no statistical difference in CCT between hypermetropic, emetropic and myopic eyes. The corneal thickness is decreasing during ageing. CCT is another clinically helpful factor for evaluation our glaucoma patients. CCT together with other risk factors can help us in establishing a target pressure. Patients after refractive surgery (PRK, LASIK) should be more carefully evaluated not to miss early stages of glaucoma.

Cornea↗
PubMed1999

[Aging and color discrimination after IOL implantation].

Colour discrimination was tested by FM 100-hue test in 106 patients (43 women and 63 men) after implantation PMMA IOL to the posterior chamber. Examined group of patients aged from 41-70 years was represented by 132 eyes. As a control were groups of healthy people (without hypertension and diabetes) of the same age categories with physiological eye findings and still clear crystalline lens. After IOL implantation the resulting total score of the test in examined patients of all decades was similar to the control group of healthy people. Even in healthy patients with IOL the colour discrimination is better beginning with 61 years (P < 0.05). Colour discrimination for red, green and blue colour has improved in comparison with the control groups and getting better with ageing. Clearly better sensitivity was in the area of green colour, it was observed in the age group starting with 61 years (P < 0.05) and for blue colour already since 51 years (P < 0.05). The improvement of colour discrimination in pseudophakic eyes in comparison with healthy population is slightly improving with increasing age.

Adult↗
PubMed1998

[Trabeculectomy with releasable sutures and corneal topography].

We are interested in the influence of trabeculectomy (TE) with releasable sutures to corneal curvature in the early postoperative period. 35 eyes of 31 patients were followed after operation. Corneal topography was made on the Topograph Opticon 2000 one day before, 1st day, 1st week, 1st month and during 6-12 months after operation. Astigmatism after operations was the highest on 1st day +3.7 D, which means elevation of about +2.8 D. During 1st month postoperative astigmatism was decreased by about 2.0 D, it is about +0.8 D more than before operation. During 6-12 months after operation temporary astigmatism nearly disappears, it only makes +0.25 D. The axis of astigmatism was without larger alterations. Small temporary changes were seen according to the place of TE. Temporary astigmatism was observed immediately after the extraction of the releasable sutures. Astigmatism after operation was influenced by the rate of filtration during the short postoperative time and also after extraction of the releasable suture.

Astigmatism↗
PubMed1997

[Normal intraocular pressure values in the Czech population].

The author investigated a group of 240 eyes of quite healthy subjects, without hypertension and diabetes in six age decades. Each age category comprised 20 female and 20 male eyes and IOP was assessed by applanation three times a day on a Goldmann tonometer (at 7.10 a.m. and 2.30 p.m.). Investigations of the healthy population above 21 years of age revealed that there is no direct correlation of IOP with age, although there is a slow increase of IOP from 41-70 years and after the age of 71 years there is a decline of IOP (P < 0.01). The mean value of IOP is 16 +/- 2.0 mmHg, in women the pressure is by 0.7 mmHg higher. The mean range of IOP in both sexes is 2.8 mmHg per day. For early diagnosis of glaucoma at least a one-day curve is essential to asses not only the absolute value of IOP but also the mean value and diurnal variation. If a subject with glaucoma and risk factors is involved, then a lower optimal individual IOP value must be considered.

Adult↗
PubMed1997

[Trabeculectomy and intraocular pressure during short-term monitoring after surgery].

The author investigated the effect of mere trabeculectomy on the reduction of intraocular pressure (IOP) and on changes of antiglaucomatous treatment six months after operation. A total of 68 eyes were operated, 24 eyes with open angle glaucoma (POAG), 24 with angular glaucoma (PACG), 4 eyes with capsular glaucoma (CG) and 16 eyes with secondary glaucoma. Six months after operation a drop of IOP by 18.2 mm Hg was recorded, the mean postoperative pressure was 12.6 mm Hg. In all operated patients the author recorded a mean reduction by two drugs used for treatment. The postoperative level is maintained between 12 and 13 mm Hg in 42 eyes without therapy (62%), in the remaining 26 eyes (38%) the mean IOP is 14.9 mm Hg with a mean postoperative therapy of 1.3 drug. When comparing the effect of operation in eyes with POAG and PACG there is a more marked decline in eyes with PACG.

Adult↗
PubMed1997

[Combination surgery (ECCE+IOL+TE) and intraocular pressure levels].

The authors investigated the effect of a combined operation, ECCE + TE + IOL, on reduction of intraocular pressure (IOP), changes in antiglaucomatous treatment and on vision six months after operation. In 1994 36 eyes were operated, 16 eyes with primary open angle glaucoma (POAG), 8 eyes with angular glaucoma (PACG) and 12 eyes with marked exfoliative syndrome (CG). Six months after operation the IOP declined from 26.4 mm Hg to 13.3 mm Hg (P 0.05), antiglaucomatous treatment was reduced from 2.55 to 1.11 (P 0.05), vision improved by 0.39, i.e. by 2-3 lines of optotypes (P 0.05). 89% of the operated patients have a vision better than 0.5. Comparison of values before and after operation revealed a more marked drop of IOP in CG (P 0.05) than in POAG.

Aged↗
PubMed1994

[Cataract extraction and intraocular lens implantation in patients with glaucoma].

The authors followed the collection of 77 eyes with glaucoma (54 eyes with POAG, 16 eyes with PACG and 7 eyes with CG) after ECCE or phacoemulsification with implantation of IOL. The patients were operated in 1990-1991 at the Ophthalmological Clinic FNKV and 3rd Medical Faculty in Prague. The authors evaluated IOP, therapy and visual acuity 6 weeks and 6 months after operation. After 6 months period IOP was decreased in average about 3 mmHg; in POAG the reduction was 1.9 mmHg and in PACG the reduction was 4.7 mmHg. In this time the authors also registered decreasing antiglaucomatous therapy at 38 eyes (i.e. 49.3% operated eyes). The reducing therapy represents 50% eyes with POAG and 69% eyes with PACG. The visual acuity is in 70% 6/6-6/12. Patients with PACG have more expressive postoperative effect. The authors draw the attention to late diagnosis CG, after successful operation the visual acuity is reduced on account of advanced changes of the optic disc.

Aged↗