Biomedical subjects

J Hildell

Publications and source records attributed to J Hildell.

10 recordsLinked to original sources

PubMed1979

Breast hamartomas. An important entity in mammary pathology.

1. Fifteen cases of a rather distinct entity of tumour-like lesion in the breast are presented. 2. They have a distinct mammographic appearance and can be easily shelled out at surgery, leaving symmetrical breasts. 3. They are well-circumscribed lumps of varying size with a smooth surface. 4. Microscopically they show normal or dysplastic glandular structures of lobules and ducts, without neoplastic features, within a prominent fibrous stroma. The lesions appear to be closely related to adenolipomas.

Adolescent↗

PubMed1979

Breast cancer screening with mammography: a population-based, randomized trial with mammography as the only screening mode.

A population-based, randomized breast cancer screening project was undertaken using mammography alone. Of 17,447 invited women aged 50-69, 12,765 (73%) attended the screening. On the basis of the screening films, malignancy was suspected in 405 women (3.2%) who were recalled for complete mammography. Additional films showed that the suspicion of malignancy was false in 194 women. The remaining 211 women (1.7%) were referred for clinical and cytological examination. Of these, 159 had surgery. Breast cancer was proved in 97 women, corresponding to a prevalence rate of 7.6/1000. Fifty-three (55%) of the carcinomas were either in situ or invasive with a diameter of less than or equal to 1 cm. Axillary metastases were found in 19 patients (19.6%). Cancers detected at screening were significantly less advanced than those in the control group. There was a remarkably high frequency of tubular carcinoma among cancers detected at screening.

Aged↗

PubMed1979

Radiographic appearances in Crohn's disease. I. Accuracy of radiographic methods.

Preoperative films of 176 patients operated upon for Crohn's disease were reviewed and compared with microscopic findings in the resected specimens in order to assess the accuracy of the radiographic techniques used. It was found that a diagnosis of the presence and the extent of the disease was often dependent on the demonstration of minor mucosal ulcers and less marked submucosal edema. These lesions were not adequately demonstrated by any of the techniques used for small bowel examination, but were consistently revealed by the double-contrast technique used for examination of the colon.

Adolescent↗

PubMed1979

Mammary hamartomas.

Five cases of mammary hamartoma are described, with special reference to the radiographic features. Hamartomas are well circumscribed lesions composed of normal or dysplastic mammary tissue. They are probably more common than has been anticipated from the literature and are important because they may be confused with other well circumscribed tumors, such as cystosarcoma phyllodes. The radiographic characteristics of hamartoma allows a tentative diagnosis in most cases.

Adult↗

PubMed1979

Radiographic appearances in Crohn's disease. II. The course as reflected at repeat radiography.

The course and distribution of the lesions in 174 patients with Crohn's disease were evaluated from preoperative films. In the small intestine the course was locally progressive. Colonic disease involved either the right hemicolon or the entire colon. Fluctuations of mucosal lesions were common and could explain the radiographic finding of segmental and left-sided colitis. Variations in the anatomy of the lymphatic system could explain the varying distribution of the lesions.

Cecum↗

PubMed1979

Mammary hamartoma, a benign breast lesion.

Hamartoma or mastoma is a benign breast lesion which is unfamiliar to most clinicians. Five cases with this lesion are presented. It is a rather soft, sharply delineated lump which may cause a considerably asymmetry of the breasts. Radiologically it appears as a circumscribed tumour with homogenous or varying density and at operation the lump is easily enucleated. Histologically it contains normal or dysplastic mammary tissue. It is unilateral and benign. The lesion is now more frequently diagnosed because of increased use of mammography and can be mistaken for a neoplasm. It is therefore important that clinicians and radiologists are acquainted with it.

Adult↗

PubMed1979

Gray scale ultrasound and endoscopic ductography in the diagnosis of pancreatic disease.

Seventy-two patients were examined by ultrasonography and endoscopic pancreaticography (ERCP) because of clinical suspicion of pancreatic disease. The following final diagnoses were obtained. Carcinoma of the pancreas: 20 patients; pancreatitis: 27 patients; other diseases: 17 patients; no organic disease: 8 patients. In this series, carcinoma of the pancreas was demonstrated with almost equal efficacy by the two methods used. Cysts in the pancreas were better demonstrated by ultrasonography, while ERCP was superior in demonstrating chronic pancreatitis. The diagnostic results with the exclusive use of one method was not satisfactory, but by combining the two methods an adequate diagnostic accuracy was obtained. Thus in the 47 patients with pancreatic disease, organic abnormalities were demonstrated by the two combined methods in 46 (98%). In 41 of the 47 patients (87%) the exact nature of the lesion could be assessed by combining the two methods.

Adolescent↗

PubMed1978

Number of projections in mammography: influence on detection of breast disease.

A total of 491 cases of breast cancer were reviewed to evaluate the diagnostic importance of the three standard projections; craniocaudal, mediolateral, and oblique. With only one projection, 90% of the malignancies would have been detected; with two and three projections the percentages rose to 94% and 95%, respectively. Nonvisualization was due to either juxtathoracic position of the tumor or superimposition of dense tissues. A relation was found between the position of a juxtathoracic tumor and the projection in which it was visualized. The mean diameter of tumors not visible due to superimposition of dense tissues was smaller than that of the whole material. In breast screening programs, use of two projections, the oblique and craniocaudal, is recommended.

Breast Neoplasms↗

PubMed1978

Percutaneous nephrostomy. Aspects on applications and technique.

Percutaneous nephrostomy was performed in 32 patients: in 8 patients for permanent and in 24 for temporary drainage. The most common indication was obstruction of the distal ureter due to malignancy. Puncture of the renal pelvis was performed with the aid of fluoroscopy and/or ultrasound. Change to larger catheters was achieved using the Seldinger technique. Complications in the form of bleeding occurred in 5 patients and were in conjunction with repuncture after the initial catheter had slipped out, or occured in connection with change to larger catheters. With the routine use of ultrasound and specially designed catheters the method should be an effective alternative to operative nephrostomy also in the nonemergency patient.

Adult↗

PubMed1976

Angiography in Crohn's disease revisited.

The diagnostic value of angiography was studied in 116 patients with Crohn's disease. Angiograms showed abnormalities in over 90% of the cases. Many angiographic features were nonspecific; only the "zoning sign" and the presence of paraintestinal mesenteric neovasculature were considered diagnostic. Crohn's colitis could be distinguished from ulcerative colitis in only 30% of the cases. Angiography, as a diagnostic adjunct to barium studies, will reveal the presence of lesions and their extent. This is particularly important in suspected postoperative recurrence of Crohn's disease. Angiography is a potential differential diagnostic aid in doubtful cases of inflammatory and malignant bowel disease.

Angiography↗