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Biomedical subjects

J Hess

Publications and source records attributed to J Hess.

At least 271 records · Page 15Linked to original sources
PubMed1982

Successful management of cor triatriatum associated with anomalous pulmonary/systemic venous connection in an infant.

Diagnosis and successful surgical repair of cor triatriatum, associated with anomalous pulmonary/systemic venous connection in a 6-month-old infant, is described. Follow-up at 2 years revealed no abnormalities. The clinical findings, hemodynamics, and surgical treatment are discussed, together with a review of the literature. This is a rare, life-threatening situation presenting significant diagnostic difficulties in infancy. It is, however, amenable to surgery provided that an early diagnosis is achieved.

Arteriovenous Malformations↗
PubMed1982

Experiences with the Fontan operation.

Up to December 1980 we performed 21 Fontan operations: 8 for tricuspid atresia and 13 for a functional monoventricle. Although palliative, the operation is currently a good method of treating tricuspid atresia. In our experience, the use of a sufficiently large atriopulmonary valved conduit assures a more satisfactory immediate postoperative hemodynamic result than the atriobulbar non-valved connection (RA-infund. tunnel). Good results can be obtained by a modified Fontan operation in patients with a monoventricle. However, with this malformation, very careful preoperative selection of patients is necessary with special regard to pulmonary vascular resistance. The connection between the right atrium and pulmonary artery was established by a valved conduit in 15 patients; no valve was incorporated in the other 6 patients. The largest prostheses gave the best immediate postoperative hemodynamic results. Two patients with monoventricle were successfully reoperated for persistent right-left shunt. The 13 patients so far followed up for at least a year show definite improvement as compared with their preoperative condition. Late complications from the valved prostheses have not been observed so far.

Adolescent↗
PubMed1982

Screening for penicillin tolerance in viridans streptococci by a simple disk method.

A disk method was developed for demonstrating penicillin tolerance in viridans streptococci. This was achieved by the substitution of the penicillin disk used for susceptibility testing by a disk containing penicillinase. After reincubation, penicillin-tolerant strains exhibited new growth in the area adjacent to this disk, providing a rapid screening test.

Drug Tolerance↗
PubMed1981

Macrophage adherence inhibition assay: measurements of adherent cells by the TV image analysis system Densitron.

A procedure is described to automate the cell counting step in the indirect macrophage adherence inhibition assay using the TV image analysis system Densitron. Comparison of the results of direct visual counting and of Densitron measurements of the adherent cells in the haemocytometer chamber indicates the qualification on principle of Densitron to substitute the time consuming and exerting visual counting procedure.

Animals↗
PubMed1980

Pulmonary atelectasis following upper urinary tract surgery on patients in the 25 degrees and 45 degrees 'jack-knife' position. A sequential analysis.

The development of pulmonary atelectasis following upper urinary tract surgery in patients positioned either in the 25 degrees or the 45 degrees 'jack-knife' position was evaluated in a randomized clinical trial with sequential analysis. Atelectasis was diagnosed from chest radiographs and/or from a decrease in arterial oxygen tension during the first three postoperative days. 32.1% of 78 patients developed atelectasis, but no statistically significant differences was found between the two positions.

Adolescent↗
PubMed1979

Indications for a brain uptake of labelled vasopressin and ocytocin and the problem of the blood-brain barrier.

Fifteen seconds after intracarotid injection of [125J]-lysine vasopressin, [3H]-ocytocin, tritiated water or [3H]-inulin, the distribution of radioactivity in 18 regions of the rat brain and in the anterior pituitary was determined. Comparing the concentration of the different tracers (in % of injected radioactivity per g brain tissue), it is assumed that a small amount of the labelled neurohormones is taken up by the brain, indicating a penetration of the blood-brain barrier and/or an accumulation within the structures of the barrier system.

Animals↗
PubMed1978

Regional net uptake of 14C-glucose by rat brain under the influence of corticosterone.

Fifteen seconds after intracarotid injection of either 14C-glucose or tritiated water in adrenalectomized rats, the net uptake of the respective tracer by 18 brain regions and by the anterior pituitary was measured. Corticosterone added to the injection solution (1 or 100 micrograms ml-1; 0.2 ml per animal) caused a dose-dependent decrease of net uptake of 14C-glucose in twelve regions. Compared to the net uptake of tritiated water which was used as a measure of relative blood flow, it suggests that this effect, at least partially, is due to a decreased blood-brain barrier permeability to 14C-glucose. Furthermore, the regional net uptake of 14C-glucose was estimated in rats with different endogenous corticosterone levels but injected with an identical solution in each case. Statistically significant differences could be observed between adrenalectomized and restrained animals in three brain regions.

Adrenalectomy↗