Search PubMed⌕ Search

Biomedical subjects

J Henry

Publications and source records attributed to J Henry.

At least 181 records · Page 10Linked to original sources

Plasma and salivary concentrations of erythromycin after administration of three different formulations.

In a 6-volunteer cross-over study the pharmacokinetics of 3 erythromycin preparations were compared. A single oral dose of 500 mg of each preparation was administered at each occasion and the levels measured in timed samples of plasma and saliva. Markedly higher blood concentrations of the estolate and propionate were obtained compared to the stearate. Comparison of serum and plasma concentration of the drugs from each split sample showed no significant differences. Plasma concentrations always exceeded those in saliva but for any one preparation a similar ratio was obtained at different times. This may be useful to ascertain compliance and to measure concentration of the compounds where direct measurement in plasma is not practicable.

Adult↗

Mental health services by and for Austrailian aborigines.

Based on a program developed for the Papago Indians of Arizona, five Australian Aborigines were trained as Behavioral Health workers, to deliver mental health services to their group. The problems of the Aborigines are very similar to those of the Indians. The training consisted of developing basic skills in interviewing, case indentification and several methods of intervention, including crisis intervention, family and alcoholism counselling. A mental health clinic was developed for the Aboriginal community for health services and training. Community projects and field trips were part of the training, as was report writing, record keeping and presentations to professional groups.

Adolescent↗

Synaptic morphology of the carotid body of the domestic fowl.

Efferent and reciprocal synapses have been demonstrated in the carotid body of the domestic fowl (Gallus gallus domesticus). Synapses were also found with purely afferent morphology, but were probably components of reciprocal synapses. The general morphology of the endings suggested the presence of two types of axon, afferent axons making reciprocal and perhaps afferent synapses with Type I cells, and efferent axons making efferent synapses with Type I cells. A few axo-dendritic synapses were also found. The dense-cored vesicles associated with the afferent components of reciprocal synapses and with the possible true afferent synapses varied in diameter and core but could belong to one population of pre-synaptic vesicles. These observations are consistent wtih a new theory for the carotid body receptor mechanism. This proposes a spontaneously discharging afferent axon inhibited by an inhibitory transmitter substance released by the Type I cell via the "afferent" component of its reciprocal synapse, the "efferent" component inhibiting this release. Besides this chemoreceptor modulation of its afferent axon, the Type I cell may also have a general secretory function.

Animals↗