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J Henrion

Publications and source records attributed to J Henrion.

64 records · Page 4Linked to original sources
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[Circulatory hyperkinesis of cirrhosis: etiopathogenesis, clinical and therapeutic implications].

A mysterious complication of cirrhosis is the progressive development of a hyperdynamic circulatory state characterized by high cardiac output and low peripheral and splanchnic arterial resistance. This particular hemodynamic state plays a major role in the progress of portal hypertension and sodium renal retention observed in cirrhosis. In this review, we try to better define the clinical impact and the etiopathogenic mechanism of the hyperdynamic state of cirrhosis.

Glucagon↗
PubMedDate not supplied

[Can the L/A ratio identify acute alcoholic pancreatitis?].

Early distinction between acute alcoholic pancreatitis is important, because of possible emergency endoscopic sphincterotomy in case of biliary pancreatitis. The aim of this study was to evaluate the value of L/A ratio in the diagnosis of acute alcoholic pancreatitis. From 1990 to end 1993, 133 patients with acute pancreatitis were reviewed. Inclusion criteria were: 1) abdominal pain, 2) pathological serum amylase or serum lipase on admission or within 24 hours after beginning or abdominal pain, 3) acute pancreatitis at the echography or CT scan within 48 hours after admission. 60 patients met the inclusion criteria (31 alcoholic pancreatitis, 19 biliary pancreatitis and 10 pancreatitis of other causes). L/A ratio was studied in terms of delay from beginning of abdominal pain. There was no statistical difference between alcoholic and biliary pancreatitis at any time of the study, with the exception of admission. AST, ALT and alkaline phosphatase were higher in biliary pancreatitis than in alcoholic pancreatitis. AST and ALT were the best biochemical tests to diagnose biliary pancreatitis. Blamey's criteria can also contribute to diagnose biliary pancreatitis. These biochemical tests are the most helpful if they are collected very soon in the evolution of acute pancreatitis. It is concluded that L/A ratio is not helpful in the diagnosis of alcoholic acute pancreatitis.

Acute Disease↗
PubMedDate not supplied

Screening for hepatocellular carcinoma: a regained enthusiasm due to new therapeutic options?

Screening for hepatocellular carcinoma arising in cirrhosis has been recommended for a long time. However, the results of this screening have been disappointing mainly because of poor health status and liver function in patients with cirrhosis. Indeed, when an hepatocellular carcinoma is discovered by screening, surgical resection can rarely be performed. Recently, percutaneous ethanol injection has emerged as an efficient and well acceptable therapeutic procedure. In this review, we report our personnal opinion on the regained interest for screening for hepatocellular carcinoma in the light of percutaneous ethanol injection.

Carcinoma, Hepatocellular↗
PubMedDate not supplied

Severe nontyphoidal salmonellosis probably in relation with omeprazole treatment: report of 2 cases.

We report 2 cases of severe nontyphoidal salmonellosis (Salmonella enteritidis), occurring 4 and 5 weeks after starting a treatment with Omeprazole (20 mg a day). No other member of the families was sick, and none of the 2 patients took any meals outside home during the two weeks preceding the first symptoms. Gastric hypochlorhydria is a major risk factor for Salmonella enteritidis, and several cases of severe infection have been described with this condition. After a review of the literature we conclude that patients with diminished gastric acid run an increased risk of developing Salmonella infection and often with a more serious clinical course.

Adult↗
PubMedDate not supplied

Hypoxic hepatitis: a difficult diagnosis when the cardiomyopathy remains unrecognized and the course of liver enzymes follows an atypical pattern. A report of two cases.

In a clinical setting of cardiac or circulatory failure, the diagnosis of hypoxic (ischaemic) hepatitis is easy and can be elicited on mere clinical and biochemical features. We report two cases of hypoxic hepatitis where cardiomyopathy remained unrecognized at admission due to the lack of conventional signs of congestive heart failure and where the increase in liver enzymes activities followed an atypical pattern, characterized by only moderate elevation of serum aminotransferases activities, low ASAT/ALAT ratio and elevated ALAT/LDH ratio. This atypical pattern not suggestive of hypoxic hepatitis, could be explained by a delay between the onset of hypoxic injury of the liver and admission to hospital. Moreover one case was complicated by frank jaundice, an unusual feature in hypoxic hepatitis. Consequently, diagnosis and appropriate inotropic treatment were delayed resulting in progressive deterioration and eventually death of both patients. The report of these two cases and the review of other similar cases previously published, enlighten some atypical features of hypoxic hepatitis.

Aged↗