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Biomedical subjects

J Henrichsen

Publications and source records attributed to J Henrichsen.

141 records · Page 8Linked to original sources

The occurrence of twitching motility among gram-negative bacteria.

Almost 1000 strains representing well above 50 different species or groups of gram-negative bacteria were examined for twitching motility. This kind of motility was mainly found in strictly aerobic cocci and rods (viz. Acinetobacter calcoaceticus, Moraxella spp., Neisseria gonorrhoeae, N. meningitidis, Pseudomonas spp., phenon 3 of Thornley that is closely related to Acinetobacter, and marine, yellow-pigmented rods), but also in the facultative Eikenella corrodens and in anaerobic strains presumptively identified as "Bacteroides corrodens" earlier. Strains of species known to possess polar fimbriae were shown to exhibit twitching motility. None of the strains of species known to possess peritrichously arranged fimbriae exhibited twitching motility.

Acinetobacter↗

The influence of changes in the environment on twitching motility.

By examining medium composition and cultural conditions quantitatively it was possible to define conditions suitable to bring twitching motility about. Such conditions include the use of freshly poured, relatively thick and only slightly dried plates of a dilute medium in which the agar concentration is not too high. Incubation should take place in a humid atmosphere. In fact, everything points to the humidity as a factor of the utmost importance. Using strains of Acinetobacter calcoaceticus, it was found that a pH value of the medium adjusted to 9.0 enhances twitching motility. Spreading growth was not produced if agarose was applied instead of ordinary agars. Twitching motility was inhibited by a number of different chlorides, potassium nitrate, Tween 80 and sodium taurocholate. Possible interpretations of these observations are discussed.

Acinetobacter↗

On twitching motility and its mechanism.

Previously published reports have established a correlation between twitching motility and the possession of polar fimbriae in all cases examined. Twitching motility was shown to be highly dependent on the availability of liquid at the agar surface. In the present paper experiments are reported that establish: 1) the dependence of twitching on the existence of a layer of liquid of a particular thickness, 2) the production of such a liquid layer surrounding areas of growing organisms, and 3) the affinity of twitching bacteria for the air-water interface. Reasoning from these facts, it is postulated that the demonstrated affinity for the air-water interface is conferred upon the cells by the polar fimbriae. It is also suggested how the movements might be generated.

Bacterial Physiological Phenomena↗

Immunization of elderly people with polyvalent pneumococcal vaccine.

On March 28-30, 1988 the World Health Organization held a "Consultation on Immunization of Elderly People with Polyvalent Pneumococcal Vaccine". The meeting was held in Copenhagen and was sponsored by the WHO Regional Office for Europe and its Health of the Elderly programme. The meeting was attended by 18 temporary advisors and three observers. One of the main conclusions of the meeting was that pneumococcal vaccination should be recommended for all elderly persons and for all persons at high risk of acquiring pneumococcal infection, regardless of age.

Aged↗

Epidemiology of Haemophilus influenzae type b infections among children in Denmark in 1985 and 1986.

A retrospective epidemiological study of invasive Haemophilus influenzae type b infections among children in Denmark 1985 and 1986 was carried out and 226 cases were identified. Of these 93% occurred in patients younger than five, corresponding to an annual incidence of 40 cases per 100,000 children aged 0-4 years, 68% occurred in patients younger than two years of age, and 6% in patients younger than six months. The annual incidences of meningitis and epiglottis were 27 and 8 cases, respectively, per 100,000 children aged 0-4 years. Of the 156 cases with meningitis four patients died and seven had severe neurological sequelae. Only 67% of the cases of meningitis had been notified.

Adolescent↗