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Biomedical subjects

J Hendriks

Publications and source records attributed to J Hendriks.

78 records · Page 5Linked to original sources

Paravertebral schwannoma with high uptake of fluorodeoxyglucose on positron emission tomography.

A paravertebral mass was discovered in a 27-year-old woman, while investigating a painful shoulder and arm. CT, MRI and fine needle aspiration cytology (FNAC) pointed in the direction of a benign mass, but positron emission tomography (PET) showed a high uptake of [(18)F]fluorodeoxyglucose (FDG), which was indicative of a malignant lesion. Pathological analysis of the thoracoscopically resected tumour gave us the final diagnosis of a benign schwannoma. This report demonstrates that a high uptake of FDG in a non-malignant mediastinal tumour is possible.

Adult↗

Feasibility and effects of decision aids.

Decision aids for patients have recently been introduced in health care. A literature review was conducted to address the following research questions: 1) which types of decision aids have been developed?; 2) to what extent are they feasible, and acceptable to patients and health care providers?; 3) do decision aids affect the decision-making process and patients' outcomes? Thirty non-controlled (e.g., one-group-only designs) and controlled studies (e.g., randomized experimental designs) were identified. Decision aids were found to be feasible and acceptable to patients and to increase the agreement between patients' values and decisions and patients' knowledge. The effects of decision aids on decisions and on patients' outcomes, including decision uncertainty, satisfaction, and health, have rarely been addressed. When studied, the beneficial effects of decision aids on these outcomes appear to be rather modest. Implications for future development of decision aids and the design of studies are discussed.

Clinical Trials as Topic↗

Pulmonary metastasectomy in a patient with malignant melanoma after a disease-free interval of 15 years.

Prognosis in melanoma patients after resection of pulmonary metastases is poor. Little information is available about the relationship between long-term disease-free interval and survival rate after pulmonary metastasectomy. We report a patient treated for malignant melanoma of the forehead who developed a pulmonary metastasis after a disease-free interval of 15 years. Lobectomy was performed, but unfortunately 12 months later the patient died of brain metastases.

Adult↗

Supraaortic vessels: a clinician's point of view.

Stroke has been recognized as the third leading cause of death in the Western World, and more than 80% of all ischemic events is caused by arteriosclerosis affecting the extracranial arteries, especially the carotid bifurcation. Carotid endarterectomy (CEA) is the gold standard for preventing stroke in symptomatic and asymptomatic patients with significant carotid stenosis, when performed in centers with low complication rates (less than 3%). Recently, the carotid artery stenting (CAS) has been proposed as an alternative procedure, although its safety compared to conventional CEA is not fully documented yet. For both techniques, an accurate diagnosis by various imaging techniques is very important regarding the risk of serious complications following surgical intervention.

Carotid Stenosis↗

Intrapulmonary lymph nodes in the differential diagnosis of solitary pulmonary nodules: case report and review of the literature.

A 49-year-old man was admitted for further investigation of a coin lesion with a diameter of 1 cm. He was a heavy smoker with no professional exposure. Since the percutaneous needle biopsy did not yield a definitive diagnosis, a thoracoscopy was performed. The solitary pulmonary nodule was found to be an intrapulmonary lymph node with anthracosilicotic pigment and a thoracoscopic wedge resection was performed. A review of the case reports in the period 1961-1993 shows that intrapulmonary lymph nodes could be more frequent than originally thought. All patients were smokers but professional exposure was not a constant finding. The differential diagnosis and management of the indeterminate solitary pulmonary nodule are discussed.

Diagnosis, Differential↗

Short-term survival after major pulmonary resections for bronchogenic carcinoma.

From January 27, 1992 to December 12, 1994, 100 consecutive patients (86 men and 14 women) with a mean age of 62.5 years underwent lung resection for a non-small cell lung cancer. Squamous cell carcinoma was predominantly found (52%), followed by adenocarcinoma (23%) and large cell carcinoma (18%). Postoperative staging was Stage 0, 1 patient; Stage I, 57; Stage II, 17; Stage IIIa, 20 and Stage IIIb, 5. Thirty-day mortality was 4% (4 patients) with 10.7% for pneumonectomy and 0% for lobectomy or lesser resection. For the whole group 1-, 2- and 3-year survival rates were 83%, 68% and 65% respectively. Survival rates for N0, N1 and N2 after 3 years were 70%, 59% and 54% respectively. In the univariate analysis, a trend to statistical significance was noted between N0 and N1 (p = 0.08). There was no difference in short-term survival between N0 and N2 which represents a highly selected group of patients with N2 disease. In the multivariate analysis the only two independent variables with impact on survival were number of pack-years and diameter of the tumour (p < 0.05). Ninety-two quality of life questionnaires (EORTC QLQ-C30) were sent to home physicians. We collected 31 questionnaires (34%) after 2.5 months. A clear relationship was not seen between complaints of pain or dyspnea and extent of resection or lung function postoperatively. Instead, the global quality of life seemed to be influenced by the extent of resection to the advantage of a lobectomy and disadvantage of a pneumonectomy. Difficulties related to quality of life analysis are discussed and future directions are given.

Adult↗