[Results of the implantation of Mueller's total endoprosthesis utilizing standard techniques].
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Biomedical subjects
Publications and source records attributed to J Hellinger.
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The articular cartilage transplantation and the half-joint transplantation necessitate the assessment of specific biological-transplantation questions as to the structure and function of the hyaline cartilage. Compared with other organ transplantations biometric and biomechanical factors have to be taken into consideration additionally. Up to now contradictory results were obtained in the animal experiment. On principle a survival of grafted non-preserved parts of cartilage seems to be possible. In clinical practice therapeutic trials for autogenous reimplantation of articular cartilage, autogenous joint surface partial transplantations and half-joint transplantations are justified. Allogenous half-joint transplantations may also be possible in exceptional cases.
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In experiments on 12 mongrel dogs, serving as models of reversible hemorrhagic shock, the influence on blood clotting and thrombocyte function was studied. Initial hypercoagulability, observed already after introduction of anesthesia, and multiplying of pathological aggregation stages dissociated from decreased number of thrombocytes suggest a considerable influence of the proceeding of reversible hemorrhagic shock on the clotting system. It is concluded that the initial hypercoagulability is not causally related to the changes of platelet function, which represent a starting mechanism for the arising of consumptive reaction in protracted and irreversible shock.
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