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Biomedical subjects

J He

Publications and source records attributed to J He.

At least 433 records · Page 24Linked to original sources
PubMed1990

[Long-term prognosis after recovery from acute myocardial infarction].

754 cases of acute myocardial infarction survivors were followed up for 28 days to 14 years, the missing rate was 1.86%. The factors influencing long-term prognosis were analyzed. Single factor analysis revealed sex, occupation, age, amount of cigarette smoked, history of stroke, and COPD, complications of heart failure, and arrhythmia, stroke and COPD, heart rate higher than 110/min, lung rales, frequency of infarction, quit smoking after infarction exerted significant influence on over all and cardiac death rate. Multiple factors Cox model analysis revealed quit smoking, complications of stroke heart failure, arrhythmia and occupation were the independent predicting factors for over-all causes of death. Frequency of myocardial infarction, quit smoking, amount of cigarette smoked, occupation, stroke were the independent prognostic factors of cardiac death.

Adult↗
PubMed1990

[Relation of changes in plasma TXB2 PGF1alpha and differentiation of signs and symptoms in traditional Chinese medicine in severe icteric hepatitis].

Clinical observations and experimental studies were made in 52 cases of chronic cholestatic hepatitis, 30 cases of chronic severe hepatitis, 30 healthy control persons, and 30 animals with experimental intrahepatic cholestasis. The results were as follows: Plasma TXB2 and PGF1 alpha were higher than their normal values both in cases of chronic cholestatic hepatitis and in cases of chronic severe hepatitis (P less than 0.01), the ratio of TXB2 and PGF1 alpha was normal in cases of chronic severe hepatitis and lower than normal value in cases of chronic cholestatic hepatitis (P less than 0.01). The cases were divided into 4 types (hepatitis due to blood stasis and blood heat, blood stasis and blood heat accompanying symptoms of fluid retention in the epigastrium, damp-heat, and composite factors) according to differentiation of symptoms and signs on the basic theories of TCM. Significant difference was found in TXB2, PGF1 alpha, PGF1 alpha/TXB2 and bilirubin when compared with each other in the 4 types of hepatitis patients (P less than 0.01). Bilirubin, TXB2, PGF1 alpha and PGF1 alpha/TXB2 in the survivors became normal or close to normal after they were treated with blood-cooling and circulation-promoting Chinese herbal medicine and prescriptions by changing their dosages according to differentiation of symptoms and signs on the basic theories of TCM. The therapeutic effect of prescription II was more satisfactory than that of prescription I. Changes of plasma TXB2 and PGF1 alpha in the experimental animals were more significant than those both in the control group and in the group treated with prescriptions I and II (P less than 0.01), but in the liver only the ratio of TXB2 and PGF1 alpha was lower than that in normal animals (P less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

6-Ketoprostaglandin F1 alpha↗
PubMed1989

Spinal cord circuits: are they mirrors of musculoskeletal mechanics?

Over the past decade, research at three different levels of sensorimotor control has revealed a degree of complexity that challenges traditional hypotheses regarding servocontrol of individual muscles: (a) The connectivity of spinal circuits is much more divergent and convergent than expected. (b) The normal and reflex-induced recruitment of individual muscles and compartments of muscles is more finely controlled than was noted previously. (c) The mechanical interactions among linked skeletal segments and their often multiarticular muscles are neither simple nor intuitively obvious. We have developed a mathematical model of the cat hind limb that permits us to examine the influence of individual muscles on posture and gait. We have used linear quadratic control theory to predict the optimal distribution of feedback from a hypothetical set of proprioceptors, given different assumptions about the behavioral goals of the animal. The changes in these predictions that result from changes in the structure and control objectives of the model may provide insights into the functions actually performed by the various circuits in the spinal cord.

Journal Article↗
PubMed1989

Photoinhibition at low temperature in chilling-sensitive and -resistant plants.

Photoinhibition resulting from exposure at 7 degrees C to a moderate photon flux density (300 micromoles per square meter per second, 400-700 nanometers) for 20 hours was measured in leaves of annual crops differing widely in chilling tolerance. The incidence of photoinhibition, determined as the decrease in the ratio of induced to total chlorophyll fluorescence emission at 693 nanometers (F(v)/F(max)) measured at 77 Kelvin, was not confined to chilling-sensitive species. The extent of photoinhibition in leaves of all chilling-resistant plants tested (barley [Hordeum vulgare L.], broad bean [Vicia faba L.], pea [Pisum sativum L.], and wheat [Triticum aestivum L.]) was about half of that measured in chilling-sensitive plants (bean [Phaseolus vulgaris L.], cucumber [Cucumis sativus L.], lablab [Lablab purpureus L.], maize [Zea mays L.], pearl millet [Pennisetum typhoides (Burm. f.) Stapf & Hubbard], pigeon pea [Cajanus cajun (L.) Millsp.], sesame [Sesamum indicum L.], sorghum [Sorghum bicolor L. Moench], and tomato [Lycopersicon esculentum Mill.]). Rice (Oryza sativa L.) leaves of the indica type were more susceptible to photoinhibition at 7 degrees C than leaves of the japonica type. Photoinhibition was dependent both on temperature and light, increasing nonlinearly with decreasing temperature and linearly with increasing light intensity. In contrast to photoinhibition during chilling, large differences, up to 166-fold, were found in the relative susceptibility of the different species to chilling injury in the dark. It was concluded that chilling temperatures increased the likelihood of photoinhibition in leaves of both chilling-sensitive and -resistant plants. Further, while the photoinhibition during chilling generally occurred more rapidly in chilling-sensitive plants, this was not related directly to chilling sensitivity.

Journal Article↗
PubMed1989

[A quantitative study of pulmonary artery systolic pressure in patients with tricuspid regurgitation using continuous wave Doppler].

Pulmonary artery systolic pressure (PASP) was assessed with simultaneous continuous wave Doppler echocardiography (CW) and cardiac catheterization (CATH) in 33 cases. There was a close correlation between CW-estimated peak pressure gradient of tricuspid regurgitation (TRPGp) and CATH-measured PASP (r = 0.96, P less than 0.0001). Excellent correlation (r = 0.96, P less than 0.0001) between CW-estimated PASP and CATH-measured PASP was also obtained. The derived regression equation was PASP = TRPGp + 1.33 kPa. When the patients had relative or pathologic pulmonic stenosis, the regression equation was corrected by pulmonary artery pressure gradient (PAPG). The regression equation became PASP = TRPGp + 1.33-PAPG.

Adolescent↗
PubMed1989

[Quantitative assessment of pulmonary arterial diastolic and mean pressure using continuous wave Doppler].

Continuous wave Doppler echocardiographic study was performed almost simultaneously with right heart catheterization in 24 patients with a variety of cardiovascular disorders and evidence of pulmonary regurgitation detected by pulsed wave Doppler. Their pulmonary arterial diastolic and mean pressure (PADP and PAMP) measured during catheterization were ranging from 5 to 70.6 (mean 30.26 +/- 18) mmHg and from 6.7 to 91.14 (mean 42.41 +/- 23.23) mmHg, respectively. The right ventricular end-diastolic pressure was within normal limit in all but one. The peak, mean and end-diastolic pressure gradients of pulmonary regurgitation (PPRPG, MPRPG and PRPGed) were calculated using simplified Bernoulli Equation and their correlations with PADP and PAMP were analysed using linear regression method. There were close correlations between all PRPGs and PADP or PAMP (r = 0.85 - 0.94, P less than 0.0001). The best equation for assessing PADP was MPRPG + 6 mmHg (r = 0.94, P less than 0.0001), for PAMP was PPRPG + 8 mmHg (r = 0.92, P less than 0.0001). It is evident that those constants in the equations should be adjusted in individual patient who has coexisting right heart failure.

Adolescent↗
PubMed1988

Mortality and apnea index in obstructive sleep apnea. Experience in 385 male patients.

Although obstructive sleep apnea (OSA) has been studied in detail for over a decade, the mortality of this disorder is unclear. We calculated cumulative survival in 385 male OSA patients. We found that those with an apnea index (AI) greater than 20 had a much greater mortality than those with AI = less than 20. The probability of cumulative eight-year survival was .96 +/- 0.02 (SE) for AI = less than 20 vs. 63 +/- 0.17 for AI greater than 20 (p less than .05). This difference in mortality related to AI was particularly true in the patients less than 50 years of age in whom mortality from other causes is not common. None of the patients treated with tracheostomy or nasal CPAP died. Eight of the patients treated with uvulopalatopharyngoplasty (UPPP) died and the cumulative survival of the UPPP-alone treated group was not different from the survival curve of untreated OSA patients with an apnea index of greater than 20. We conclude that OSA patients with an apnea index of greater than 20 have a greater mortality than those below 20 and that UPPP patients be restudied after therapy. If the latter patients are found not to have marked amelioration of their AI, then they should be treated by nasal CPAP or tracheostomy.

Actuarial Analysis↗