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Biomedical subjects

J Haut

Publications and source records attributed to J Haut.

At least 91 records · Page 5Linked to original sources

[Prevention of bilateralization of idiopathic retinal detachment by treatment with argon laser].

The incidence of bilateral retinal detachment ranges from 12 to 15%. A retrospective study including of 141 patients with a systematical prophylactic treatment of the fellow eye is reported. After the prophylactic photocoagulation no bilateral retinal detachment occurred, no complication arose. The average follow-up was about 18 months. The authors describe the technique of the prophylactic argon laser treatment. This photocoagulation associates a focal treatment excluding suspicious lesions, and a 360 degree equatorial treatment, completed by several anterior radial rows and by a scattered but tight photocoagulation from the equator to the ora. The authors conclude that prophylactic and systematical treatment is safe and effective, avoiding the focal retinal detachments, anterior giant tears and probably many breaks. The follow-up is still too short to know the longterm percentage of bilateral detachments with such a treatment of the fellow eyes.

Adult↗

[Adverse effects and complications of argon laser trabecular retraction: practical results].

Argon laser trabeculoplasty is learned and used much more easily than filtration surgery. This explains the danger of its being abusively employed, as well as the existence of complications such as an aggravated glaucoma condition (1 to 3% of the cases). In 253 eyes afflicted with various forms of chronic open angle glaucoma with follow-ups ranging from at least 6 months to 4 years, the following complications were disclosed: 3% of the cases required treatment for severe anterior uveitis; anterior synechiae occurred in 23%, including one case of circular anterior synechiae and 4 other cases in which acute angle closure glaucoma developed several months later; trabecular hemorrhage in 6%; post operative intra ocular pressure elevation in 13%. This last complication is the most dangerous especially in advanced glaucoma: it very frequently happens during the first post operative hours in the absence of preventive treatment and it can arise up to three weeks after the procedure. In 33 cases upon 253 (13%), the pressure increase, despite a systematic preventive treatment, ranged from +3 mmHg to +16 mmHg above the baseline level in more than two thirds of these particular cases (+5 mmHg in only 7.5% of the cases and +9 in only 3.5%). In 59 eyes treated by less intensive trabeculoplasty (50 burns upon 180 degrees trabeculoplasty ring), the pressure increased in only 3.4% of the cases but the long term efficacy was reduced. Argon laser trabeculoplasty complications are less numerous than those of surgery, but some of them, i.e. intra ocular pressure elevation, can be very serious and must lead to a study of the risk-benefit ratio corresponding to the glaucoma stage which is to be treated.

Follow-Up Studies↗

Study of the first hundred phakic eyes treated by peripheral iridotomy using the N.D. Yag laser.

Performing a peripheral iridotomy with a ND Yag laser is a simple and efficient technique, with no side effects, no need for anaesthesia other than local and no surgical opening of the eye, with all the risks it entails. Out of 100 cases, 100% were a success from a technical point of view, and we observed no lesion of the lens which could have caused cataract. This out-patient technique, causing fewer complications than with Argon laser, can be used on any patient, whatever the age and the state of the angle, who has to be treated by peripheral iridotomy. The Neodymium Yag laser (ND: Yag) is a pulsed solid laser (1, 2, 3, 8, 29, 31). It cuts tissues (photodisruption) by means of a shock-wave produced by optical breakdown (plasma formation). Its effect is different from that of the Argon laser which burns tissues (photocoagulation). The present study, of 100 cases, deals with the use of ND: Yag in peripheral iridotomies.

Adult↗

Digestive tract and renal small vessel hyalinosis, idiopathic nonarteriosclerotic intracerebral calcifications, retinal ischemic syndrome, and phenotypic abnormalities. A new familial syndrome.

A new familial syndrome that affected 3 of 7 siblings is described. All 3 patients were young women with a very peculiar phenotype, poikilodermia and hair greying, and idiopathic nonarteriosclerotic cerebral calcifications. Pathological studies demonstrated a marked and progressive hyalinosis involving capillaries and often arterioles and small veins of the digestive tract, kidneys, and calcified areas of the brain. Using electron microscopy, we found that the hyalin substance in the intestinal capillaries consisted of several concentric layers of basal membrane-like deposits within a finely granular fluffy material. Huge deposits of this material were present in the subepithelial and mesangial spaces of the kidneys. Endothelial cells and, in the kidneys, mesangial cells were markedly abnormal, and a true mesangiolysis pattern was present in 2 patients. The clinical and biologic expression of these vascular changes was variable. Diarrhea, rectal bleeding, malabsorption, and protein-losing enteropathy were the main and lethal clinical problems in the proband. Hypertension appeared in the early stage of a second pregnancy in 1 sister, and mild proteinuria was found in all 3 affected patients. Peripheral retinal ischemic syndrome and chorioretinal scars were found in the ocular fundi of both affected sisters of the proband. A subarachnoid hemorrhage, due to a right sylvian aneurism, also occurred in both sisters and was lethal in 1 sister. None of the known causes of distal vessel hyalinosis could be ascertained.

Adult↗

Circular subtotal retinectomy and inferior semicircular retinotomy. Material and results in 38 cases.

Anatomical and functional results in 38 eyes with retinal detachment and major proliferative vitreoretinopathy (C3, D1, D2) treated by more or less wide retinotomy or circular retinectomy; 50% of the retinae have reattached, with an improvement of the visual function in 12 cases out of 21. The best procedure in these cases seems to be a retinotomy of at least 180 degrees on an eye filled with silicone oil to prevent secondary retractions. Circular retinectomy has been given up for retinotomy.

Adolescent↗