Friedreich's ataxia selectively involves the large neurons of the dorsal root ganglia.
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Biomedical subjects
Publications and source records attributed to J Hasson.
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Although juvenile nasopharyngeal angiofibroma (JNAF) usually presents as a mass in the nasopharynx, the primary manifestation may, in rare instances, occur intraorally. We observed such a case in a 12-year-old boy. The clinical finding of hemorrhage from the nasopharynx or contiguous areas in a male adolescent is an important diagnostic clue which should alert the clinician to the possibility of JNAF as the underlying cause.
This is the seventh reported case of soft tissue sarcoma attributed to thorotrast extravasated during the course of an injection for arteriography. An extraskeletal osteosarcoma occurring the cervical region of a 51-year-old man 30 years after a cerebral arteriogram is presented. The other reported cases include a fibrosarcoma, two neurofibrosarcomas, two spindle cell sarcomas, and an extraskeletal chondrosarcoma. The latency period has varied from 5 to 30 years. The thorotrast granules are readily identified in macrophages near or adjacent to the tumor, and the demonstration of alpha tracks on autoradiographs is diagnostic.
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