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Biomedical subjects

J Harris

Publications and source records attributed to J Harris.

At least 487 records · Page 27Linked to original sources

Total hip replacement in inflammatory hip disease using the Charnley prosthesis.

The Charnley low-friction arthroplasty was performed on 73 hips in 55 patients with inflammatory joint disease, usually for intolerable pain. Sixty-five of these operations were reviewed at a special clinic or by postal questionnaire; 57 hips were painfree or gave rise to only occasional discomfort, in 58 there was an increased range of movement, and in 46 of the 59 hips assessed clinically, the results were excellent or good. The most serious complication was deep infection, which occurred in 7 operations.

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Total hip replacement in osteoarthrosis using the Charnley prosthesis.

Charnley low-friction arthroplasty was performed on 352 osteoarthritic hips, usually because of severe pain. Three hundred and twenty hips were reviewed at a special follow-up clinic or by postal questionnaire. After operation 89% of hips were pain-free or caused only occasional discomfort, and in 76% there was an increased range of movement. Of those patients actually seen for review 79% were judged to have a good or excellent result. The most frequent single complication was deep infection, which occurred in 5.3% of hips.

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The absorption and secretion of water and electrolytes across the healthy and the diseased human colonic mucosa measured in vitro.

An ;in-vitro' technique is described for measuring quantitatively the absorption and secretion of water and electrolytes, the short circuiting current, and the simultaneous bidirectional flux rates of ions across the healthy and diseased colonic mucosa. The results show that the normal colon absorbs both sodium and water and secretes potassium. In both ulcerative colitis and Crohn's disease there is a reversal of sodium and water flux and potassium secretion is increased.A measure of the simultaneous bidirectional flux rates under conditions of zero potential has allowed us to use the Ussing equation to analyse some of the factors involved in sodium transport across the healthy and diseased mucosa.

Adult↗