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Biomedical subjects

J Handa

Publications and source records attributed to J Handa.

At least 145 records · Page 8Linked to original sources
PubMed1987

[Association of subdural hematoma and middle fossa arachnoid cyst: report of 3 cases and a review].

Three cases of arachnoid cyst of the middle fossa associated with subdural hematoma were briefly reported. In all three cases diagnosis was confirmed by CT scan and operation. A review of the literature found reports of 21 similar cases with adequate descriptions of clinical and radiological data for analysis. Of a total of 24 such cases including our 3 patients (Group B in Table 2), 21 were male and only 3 were female. The arachnoid cyst was found on the left side in 18, on the right side in 5 and bilaterally in the remaining one. Thirteen patients were in age 11 through 20. When compared Group B with Group A comprising 153 cases of arachnoid cyst of the middle fossa irrespective of presence or absence of associated subdural hematoma, such an association was seen most frequently in the male teenagers, probably reflecting the higher incidence of head injuries.

Adult↗
PubMed1987

[Oligodendroglioma of the lateral ventricle--report of 2 cases and a review].

Oligodendrogliomas rarely grow primarily in the ventricles. When compared to more common hemispheric counterparts, such intraventricular oligodendrogliomas, or oligodendrogliomas of the midline group (Martin), present distinct clinical features, namely, (1) they occur in the younger age, (2) an interval between clinical onset and diagnosis or operation is shorter, and (3) initial symptoms are most often limited to those of increased intracranial pressure, although the patient may occasionally present mild organic dementia, callosal disconnection syndrome, and/or mild gait ataxia. Two cases of oligodendroglioma primarily involving the lateral ventricle are reported in female patients, aged 29 and 19, respectively, with sole complaints of an increased intracranial pressure. Magnetic resonance imaging proved to be most useful as a radiologic diagnostic procedure. The tumor was radically removed via a para-falcine transcallosal approach without causing any persistent neurological deficits. Merit and demerit of the approach are briefly discussed.

Adult↗
PubMed1986

Fetal origin of the medulloblastoma: evidence from growth analysis of two cases.

Growth analysis of medulloblastomas was performed in two children. They initially manifested symptoms at the age of 3 years and 9 months and at the age of 2 months respectively. Computerized tomography (CT) scans were obtained at different points in each case. The growth curves were drawn on a semilogarithmic graph by calculating the tumor volume on CT on the assumptions that the tumor started from a single tumor cell and that the growth rate was constant. By extrapolating the curves back, tumor inception was estimated to have occurred respectively at the 14-23rd week and at the 16-17th week of gestation. Additional cell kinetic data were obtained from DNA analysis of surgical pathology specimens. Calculated cell-cycle times were 22-32 h for both cases. The S phases comprised 26.3% and 27% and the G0G1 phases 66.8% and 62% of the cell cycle, respectively, for case 1 and 2. Assuming a labelling index of 14%, the cell loss factors were estimated to be 97% and 74% (case 1 and case 2 respectively). The seventeenth week of gestation in humans corresponds to the timing of events occurring postnatally at days 3-18 in the developing cerebella of rodents, i.e., at the time of maximal activity in the migration and differentiation of the cells of the fetal external granular layer. Medulloblastomas have been experimentally induced in rodents by the injection of oncogenic viruses during the neonatal period, and statistical data on the epidemiology of human medulloblastomas have suggested a possible association with the contamination of polio vaccine by the SV 40 virus.(ABSTRACT TRUNCATED AT 250 WORDS)

Cell Cycle↗
PubMed1986

A rare anomaly of the axis: report of a case with shaded three-dimensional computed tomographic display.

A rare anomaly of the C-2 vertebra (axis) was found in a 54-year-old man with myelopathy. In addition to spina bifida of C-2 and abnormal articulations between C-2 and C-3, the lamina of the axis was separated from the rest of the posterior arch on each side, and the free dysplastic laminae and spinous process invaginated deeply into the spinal canal. The condition differed from the infrequent but previously described cervical spondylolysis in that the pars interarticularis and the pedicle were not dehiscent. Shaded three-dimensional computed tomographic display proved most useful in demonstrating this complicated osseous anomaly.

Axis, Cervical Vertebra↗
PubMed1986

Porous hydroxyapatite ceramics for use in neurosurgical practice.

Hydroxyapatite ceramics have been increasingly used as an inert prosthetic material in the practice of reconstructive surgery and dentistry. However, the use of this material, which has excellent biostability and biocompatibility, has not yet been popular with most neurosurgeons. The purpose of this paper is to describe three kinds of prosthetic devices made of porous hydroxyapatite ceramics that we have found useful in neurosurgical practice.

Biocompatible Materials↗
PubMed1986

Progressive neurological deficits with benign intracerebral cysts. Report of two cases.

Two patients with benign intracerebral cysts are reported and a brief review of the literature is given. Although computerized tomography (CT) scanning is useful in detecting a variety of intracerebral cysts, the CT findings are not specific for any lesion. An exploratory operation with establishment of an adequate route of drainage and a histological examination of the cyst wall are mandatory in the management of patients with a progressive but benign lesion.

Adult↗
PubMed1986

[Osteoplastic laminectomy using hydroxyapatite ceramic implants].

Cervical osteoplastic laminectomy using ceramic or apatite beads as implants was performed in 31 patients with symptomatic cervical bony canal stenosis. Patients with degenerative changes such as osteochondrosis or disc herniation are included in this study but those with spinal cord tumor, arachnoid cyst or ossification of the posterior longitudinal ligament are not. Initially foraminotomies were performed at the C5-8 levels in an attempt at preventing worsening of radicular signs caused by posterior displacement of the cord and resultant tethering effect on the nerve root. Connecting the medial borders of the foraminotomies, laminae were removed in a single piece. A small suboccipital craniectomy and C1-2 laminectomy were added when necessary. Laminae were replaced maintaining an increased anteroposterior diameter of the bony canal, by means of interposition of apatite or ceramic beads of appropriate size between the cut surfaces of the laminae. Results were excellent in 13 (42%), good in 10 (32%), fair in 4 (13%), no change in 2 (6.5%) and worse in 2 (6.5%). Literature on the osteoplastic laminectomy (laminoplasty) for cervical canal stenosis was reviewed and the advantage of the present method was briefly discussed.

Adult↗