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Biomedical subjects

J Haendle

Publications and source records attributed to J Haendle.

At least 19 recordsLinked to original sources

[Importance of intravenous digital subtraction angiography in the diagnosis of aneurysms in the region of the abdominal aorta].

The arterial vessels can be examined with satisfactory relevance via intravenous DSA using a relatively small amount of contrast medium. An aneurysm first diagnosed via sonography in the region of the abdominal aorta was confirmed in this manner in 19 patients. In 7 of these cases, it was also possible to diagnose a stenosis in the renal artery region. This method can supply exact information on the size, position and extension of the aneurysm--since the equipment has been technically improved--even in the case of kinking of the vessels. It can also supply information in the relationship of the aneurysm to visceral arteries, on the degree of calcification of the vessel walls, and on the additional occurrence of vascular stenoses. Hence, we are of the opinion that intravenous DSA is the method of choice after sonography has been performed and that it is superior to CT within the framework of preoperative examinations of aneurysms of the abdominal aorta.

Angiography

[Digital radiography. Equipment technology and initial clinical results of digital angiography with an electronic universal work station].

Using a prototype of an electronic, universal examination unit equipped with a special x-ray TV installation, spotfilm exposures and digital angiographies with high spatial resolution and wide-range contrast could be made in the clinic for the first time. With transvenous contrast medium injection, the clinical results of digital angiography show excellent image quality in the region of the carotids and renal arteries as well as the arteries of the extremities. The electronic series exposures have an image quality almost comparable to the quality obtained with cutfilm changers in conventional angiography. There are certain limitations due to the input field of the 25 cm x-ray image intensifier used. In respect of the digital angiography imaging technique, the electronic universal unit is fully suitable for clinical application.

Angiography

[Digital subtraction angiography with dynamic color function images].

The authors present for the first time the principles and initial results of a laboratory pilot plant with which parametric colour images can be produced in real time. These images are digital function images of the type originally made widely known by Höhne et al. The colour function images can be produced during conventional digital subtraction angiography (DSA) practically as a sideline, that is to say, with a minimum of time and effort, as a parallel product. Despite the fact that the course of the functional processes can be visualised dynamically, the only feature required is the storage capacity of a single digital TV screen image. Of course, the colour function image is not a substitute for exact quantitative evaluations. However, it does furnish a rapid survey of haemodynamic processes for a multitude of patients in routine diagnosis.

Analog-Digital Conversion

Tomoscopy: dynamic layer imaging without mechanical movements.

A tomographic system in which electronic movement of the x-ray source and the image receptor replace the mechanical movement of conventional tomography has been constructed and tested. Because the system permits very short, rapidly repeated exposures, viewing by television provides real-time fluoroscopic tomography, termed tomoscopy. Further, electronic adjustment of tomographic layer height permits rapid direct search for the optimum layer. The system requires no more than conventional fluoroscopic radiation levels and resolves 3 line pairs per millimeter (LP/mm) in the televised image and 4 LP/mm in the spot film images. It offers rapid, highly customized, high-resolution tomography under direct fluoroscopic control. Precise percutaneous biopsy with integrated needle-controlled equipment and tomography of contrast-filled blood vessels incorporating digital subtraction principles are theoretic possibilities.

Biopsy, Needle

[Digital radiography].

Digital radiography is a generally accepted term comprising all x-ray image systems producing a projected image which resembles the conventional x-ray film image, and which are linked to any type of digital image processing. Fundamental criteria of differentiation are based on the production and detection method of the x-ray image. Various systems are employed, viz. the single-detector, line-detector or fanbeam detector and the area-beam or area-detector image converters, which differ from one another mainly in the manner of conversion of the radiation produced by the x-ray tube. The article also deals with the pros and cons of the various principles, the multitude of systems employed, and the varying frequency of their use in x-ray diagnosis work.

Angiography

[Tomoscopy].

UNLABELLED: Report on initial clinical experience with a new form of tomography with fluoroscopy, called 'tomoscopy'. PRINCIPLE: Several grid controlled x-ray tubes firmly mounted (stationary) in circular fashion -- with the foci in equidistance -- are fired in sequential fashion for a short exposure, which creates the impression of tube movement mandatory in conventional tomography, by this sequential firing of several tubes (in 1/50 second total), the mechanical tube motion of conventional tomography can be avoided. In the image intensifier, there is synchronous electromagnetic deflection of the image between input- and output screen; and a tomographic image can be seen at the output screen. This can also be recorded on camera. This new technique allows quick fluoroscopic determination of the ideal 'cut' and thus provides efficient tomography without slowing down the ongoing examination; and it is a useful addition to modern radiographic equipment with image intensification, especially when used with contrast material. Its full future impact on diagnostic radiology can yet not be estimated.

Fluoroscopy

X-ray-induced mitotic recombination in Drosophila melanogaster. IV. Distribution within eu- and heterochromatin.

By using suitably marked X-chromosomes it was possible, on the one hand, to distinguish between induced mitotic recombination in euchromatin and in heterochromatin and, on the other hand, to get some ideas about the distribution of the recombination events within the euchromatin. These results have been taken as a basis for discussing the question: To what extent is induced mitotic recombination a simple breakage-fusion mechanism and to what extent is it comparable to meiotic recombination? Furthermore, the results give evidence that must be considered when recombination data are used to make mitotic maps.

Animals