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Biomedical subjects

J Haas

Publications and source records attributed to J Haas.

312 records · Page 18Linked to original sources
PubMedDate not supplied

[Results of low-dose treatment of oligozoospermia with clomiphene citrate].

30 oligozoospermia patients from the andrologic outpatient service of the University-Hospital for Gynecology and Obstetrics, Graz, Austria, received a treatment with clomiphene-citrate. A doses of 25 mg daily was given for 25 days, followed by a break of 5 days. This treatment cycle was repeated three times, providing a total of 4 months of therapy. Rigid criteria of selection were applied for the patients in this trial, pretreatment serum levels of FSH, LH, testosterone, prolactin and estradiol had to be in normal or low-normal range. After treatment FSH, LH and testosterone were re-evaluated and a semen analysis was performed. Six to eight weeks afterwards another spermiogram was done. A significant raise of sperm density was observed immediately after treatment and at the control 6-8 weeks after therapy. Motility and morphologic quality remained unchanged after the therapeutic course. Fructose content of seminal plasma raised significantly 6-8 weeks after therapy. FSH, LH and testosterone increased also on a significant level. 6 pregnancies could be achieved, no negative side effects of treatment had to be registered.

Clomiphene↗
PubMedDate not supplied

[Norfloxacin treatment of asymptomatic bacteriospermia in male subfertility].

20 patients with pathospermia and asymptomatic bacteriospermia of more than 10(5) bacteria/ml received an oral treatment with 800 mg Norfloxacin daily for ten days. An complete spermiogram including motility assessments with laser-Doppler-spectroscopy, round-cell counts, evaluation of number and types of microorganisms was performed before treatment and within one week after treatment. As results, a statistically significant decrease of number of bacteria and round-cells was observed in the ejaculates, whereas the other spermiogram-parameters remained unchanged.

Bacterial Infections↗
PubMedDate not supplied

[Intrauterine growth--normal curves for gestational age].

We calculated new birthweight, length and head circumference standards for caucasian boys and girls between 26 and 43 weeks gestation from 28,126 singleton live births at our hospital between 1980 and 1985. Only stillbirths and infants with serious congenital abnormalities were excluded, whereas babies born to mothers suffering from complications known to affect fetal size were considered part of the population to which standards will be applied and thus remained included. The standards were determined from centiles for each gestational week independent of the mode of distribution of the data. The centiles were then "smoothed" using a Hanningfilter. The descriptive analysis showed a skew to the left of all our data and a steep distribution pattern so that the assumption of a normal distribution is incorrect. Comparison with mean values and standard deviations computed from the same data revealed considerable deviations from our results.

Birth Weight↗
PubMedDate not supplied

Severe hypoglycemia in children and adolescents with IDDM: frequency and associated factors.

Severe hypoglycemia is a very common complication in youths with insulin-dependent diabetes mellitus (IDDM). Seventy four children and adolescents were surveyed for a 1-year period to evaluate the frequency and associated factors of severe hypoglycemia. Patients or their parents completed a standardized questionnaire which inquired about severe and mild episodes, treatment, and prevention of hypoglycemia. Forty-four percent of the patients experienced at least one severe hypoglycemic episode [need for assistance (grade III), loss of consciousness with or without convulsions (grade IV)] during the survey period. The event rate was 0.77 episodes (grade III and IV) per patient-year. The group with severe hypoglycemic episodes was significantly older (mean age, 16.3 years; SD, 3.6 years versus mean age 13.7 years; SD, 4.9 years; p = 0.01) and had significantly longer duration of diabetes (mean, 8.2 years; SD, 4.3 years versus mean, 6.1 years; SD, 4.0 years; p = 0.04) than the group without severe hypoglycemic episodes. There were no significant differences in mean glycosylated hemoglobin (HbA1c), daily doses of insulin, type of insulin regimen, gender, and age at diagnosis between patients who reported severe episodes and those who did not. Mild hypoglycemia was reported by 72 patients. Fifty percent of the patients recognized potential precipitating factors. Older age and longer duration of diabetes seem to predispose the patient to severe hypoglycemia. This may be the result of a diminution of the counterregulation system including lower neuroadrenergic reaction, or the still unphysiologic treatment of diabetes. Continued vigilance and education is important in older adolescents with longer duration of diabetes.

Adolescent↗