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Biomedical subjects

J H Morton

Publications and source records attributed to J H Morton.

At least 19 recordsLinked to original sources

A rational screening and treatment strategy based on the electrocardiogram alone for suspected cardiac contusion.

The charts of 71 patients admitted to one teaching institution over a 4-year period with a primary or secondary diagnosis of "rule out cardiac contusion" and of another 62 admitted to a second institution with more severe injuries and suspicion of cardiac contusion were reviewed to determine if mortality or morbidity would have occurred if all patients with normal electrocardiograms (EKGs) in the emergency department (ED) were discharged (or admitted to unmonitored beds for other injuries). Only 13 patients developed cardiac problems: two elderly patients died in the ED, while the others experienced arrhythmias or, less commonly, pump failure requiring treatment or observation. All 13 had EKG changes present while still undergoing evaluation in the ED: 11 had a specific problem on arrival, 1 developed a problem while still being evaluated in the ED, and the 13th had what was probably an iatrogenic problem. Importantly, 5 of 12 patients had normal creatine phosphokinase-MB fractions, and 5 of 9 had normal echocardiograms. No patient with a normal EKG had subsequent cardiac problems. Operative intervention for other injuries was necessary in 26 patients overall, and there was no cardiac morbidity. We conclude that had the EKG been used as the sole screening tool, approximately 25% of these patients could have been discharged from the ED without missing problems. In addition, management would have been greatly simplified, and the hospital would have realized substantial savings, both in terms of direct costs and in the freeing of valuable and scarce resources.

Adult

Gastric rupture from blunt abdominal trauma.

Gastric rupture from blunt abdominal trauma is a rare occurrence. Six patients are presented and reviewed with the literature since 1930. Several features of the diagnosis and management of this injury are emphasized, including a strong association with thoracic trauma and a high incidence of intra-abdominal abscess formation which results from massive intraperitoneal contamination. Mortality is not usually from gastric rupture per se, but rather from concomitant vascular or neurologic injury. The key to survival for these patients is early operative intervention and an aggressive approach to reoperation and drainage of abscesses.

Abdomen, Acute

Acute mesenteric ischemia.

Forty-nine patients with acute mesenteric ischemia have been treated during the past 15 years. The overall mortality rate was 65%; the prognosis varied with the cause of disease. None of the 12 patients with primary thrombosis of the mesenteric arteries, 5 of 14 with spontaneous embolization, and 2 of 4 with arterial occlusion subsequent to diagnostic angiography survived. Seven of 11 patients with primary mesenteric venous thrombosis and 2 of 7 patients in whom mesenteric ischemia was related to low flow unassociated with occlusion of either the major arteries or veins survived. The only patient with occlusive arterial vasculitis survived. Thirty-one of these 49 patients presented with peritoneal signs. The serum glutamic oxaloacetic transaminase, lactic dehydrogenase, and creatine phosphokinase levels were significantly elevated in patients with nonocclusive ischemia and less elevated in patients with arterial or venous thrombosis. By contrast, the enzyme levels were frequently normal in patients with arterial embolization. Angiography was diagnostic in all four patients who were evaluated with this procedure--three patients with arterial embolization and one patient with nonocclusive ischemia. This procedure should be used more frequently, especially when embolization is suspected. The value of reexploration was assessed. There were 17 reexplorations, with only three contributing to survival (17.7%). Two patients with mesenteric venous thrombosis and one patient with arterial embolization benefited from resectional therapy during reexploration. The study emphasizes that diagnostic criteria, therapy, and prognosis can be correlated with the etiologic factor.

Acute Disease

Fluid replacement in patients with large-area, full- and partial-thickness burns.

The importance of fluid replacement therapy in large-area, full- and partial-thickness burns has become widely recognized in the past 35 years. Experimenters have proposed various intravenous solutions and various ratios of fluid to body weight and percentage of body area burned. The importance of colloid and plasma during the early resuscitation phase has been questioned. The role played by age, by physical condition, and by individual response to injury in determining the patient's therapeutic needs has also been widely recognized. All physicians should bear in mind the need for careful observation of the patient in association with an understanding of the pathophysiology involved in treating burn shock.

Adolescent