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Biomedical subjects

J H Jensen

Publications and source records attributed to J H Jensen.

At least 37 records · Page 2Linked to original sources

Analysis of equipotential lines as a basis for impedance imaging.

A mathematical two-dimensional phantom model has been implemented. With this it has been possible to calculate the equipotential line patterns in a homogeneous medium with inhomogeneous inclusions. The results have been compared with measurements in a physical phantom with identical outline. The shape of the phantom can be adapted to varying outlines congruent with transections of the human body. The physical measurements verify closely the pattern of the equipotential lines. Three approaches are suggested in applying the mathematical phantom model as a useful tool in impedance imaging.

Humans↗

Post-tonsillectomy haemorrhage and analgesics. A comparative study of acetylsalicylic acid and paracetamol.

In a prospective randomized clinical study the incidence of post-tonsillectomy haemorrhage was studied in 832 patients receiving either acetylsalicylic acid or paracetamol as postoperative analgesic (423 and 409 patients, respectively). Of 27 patients experiencing 1 or more bleeding episodes postoperatively, 18 received acetylsalicylic acid and 9 paracetamol. No difference was found regarding the incidence of bleeding within the first 24 h but, later on, a significantly lower incidence of secondary bleeding occurred in the paracetamol group (0.5%) compared with the acetylsalicylic acid group (3.1%). We conclude that acetylsalicylic acid is not the optimum postoperative analgesic following tonsillectomy and that other alternatives must be sought.

Acetaminophen↗

Silastic coated incus in tympanoplasty: a preliminary report.

In 54 ears lacking the stapedial arch and the long process of the incus, ossiculoplasty was performed with a shaped auto- or homologous incus as columella. In 29 of the ears, the deep, slender part of the columella was coated with a silastic tube in order to prevent adhesions and dislocation. One year after the operation the functional results were similar in patients with silastic coating of the incus to those without. It is concluded that the less satisfactory results of tympanoplasty in such ears are primarily caused by factors outside the niche of the oval window. Possible ways of improving the results are discussed.

Adolescent↗

Routine radiological examination of the sinuses before septoplasty.

Records of septoplasties performed during the last five years were reviewed with the aim of evaluating the results of routine pre-operative radiological examination of the sinuses. A positive correlation was found between the information of sinusitis within the last two years and the radiological finding of complete density or fluid. The roentgenograms showed normal conditions in 73 per cent of the cases and various degrees of pathology in 27 per cent; no case showed signs of malignancy. Puncture and irrigation or sinoscopy had been performed in 52 per cent of the cases with pathological X-rays. Following this treatment, surgery was postponed in 12 patients, and in nine patients a drainage tube was placed in the maxillary sinus peroperatively. Complications developed post-operatively in five of these nine patients and it is concluded that septoplasty should have been postponed. We find that it is important to identify the four per cent (12 + 9) of patients in whom the radiological findings are so pronounced that operation ought to be postponed.

Adolescent↗

Perilymph fistulas caused by myringotomy.

Two cases of rupture of the round window membrane verified by operation are presented. Both cases arose in connection with myringotomy and were presumably caused by a violent force acting directly on the tympanic membrane and the ossicles. This would result in a strong movement of the stapes and an acute change in the perilymph pressure, thereby causing an indirect injury to the round window. Symptoms and treatment are briefly discussed.

Acute Disease↗

Serum angiotensin-converting enzyme in sarcoidosis and psoriasis.

Untreated pulmonary sarcoidosis is associated with an increased level of serum angiotensin-converting enzyme (SACE), which is regarded as a valuable method of diagnosing sarcoidosis and measuring the activity of the disease. The level of SACE in cutaneous sarcoidosis or other skin diseases has not been clearly established. We therefore examined SACE in 31 patients with systemic sarcoidosis, including cutaneous manifestations, and 12 patients with isolated cutaneous sarcoidosis. Also, 23 patients with psoriasis were studied. The level of SACE was generally elevated only in patients with untreated systemic sarcoidosis, whereas it was normal in cutaneous sarcoidosis and psoriasis. If the level of SACE is elevated in "isolated" cutaneous sarcoidosis, systemic disease must be strongly suspected.

Female↗

Plasma fibronectin in acute myeloid leukaemia.

In 13 patients with acute myeloid leukaemia (AML), plasma fibronectin (P-FN) was measured before, during and after chemotherapy. Pre-treatment concentrations of P-FN were within the reference range and significantly higher than the nadir value (p less than 0.05). A rise in body temperature by more than 1 degree C induced a significant fall in P-FN (p less than 0.05) and transfusion with freshly drawn blood products could prevent this fall. P-FN concentrations were significantly higher in patients obtaining complete haematological remission than in patients in whom remission could not be induced (p less than 0.001). This difference could not be attributed to transfusion or febrile episodes.

Adult↗

Congenital thymic cysts in the neck.

Cervical thymic cysts are rare. Sixty-seven cases are reported in the literature up until 1982. Remnants of thymic tissue in the course of descent may lead to cystic development. The majority of the cases is found in males under 10 years of age, typically on the left side of the neck. The characteristic histological features are thymic tissue with Hassall's corpuscles and cholesterol clefts found in the cyst wall. A preoperative correct diagnosis has never been made. Typically, the templative diagnosis has been a common branchial cyst. An additional case of a thymic cyst is reported, here. Surgical removal was complicated by lesion of the vagal nerve, which has never been described, although the cysts are often adherent to the carotid sheath and vagal nerve.

Child↗

Hearing loss in children with abnormal corneal thickness.

Corneometry, i.e. measurement of the thickness of the centre of cornea, has been introduced as an objective method for the diagnosis of ecto-mesodermal insufficiency. A group of children, between 4 and 18 years of age with different types of hearing defects has been examined by this method and the results were evaluated separately for conductive and sensorineural hearing loss. Within the two groups, the cornea-positive children (i.e. children with abnormal corneal thickness) were analyzed in relation to the different diagnostic groups.

Adolescent↗

Two cases of anomalies of the bronchi combined with cancer in the lung.

Two cases of right-sided bronchus anomalies are described. These represent two groups, stated in the literature to be the commonest anomalies, viz. displaced apical bronchus and bronchus cardiacus superior. The first case was combined with an epidermoid carcinoma localized to the displaced apical bronchus and was found during surgery. In the second case, the anomaly was diagnosed by bronchoscopy and verified by thoracotomy with bilobectomy for adenocarcinoma. Anomalies of these types should be borne in mind in the bronchoscopic assessment of the operability and treatment of benign and malignant pulmonary disease.

Bronchi↗