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Biomedical subjects

J H Husøy

Publications and source records attributed to J H Husøy.

5 recordsLinked to original sources

"Probability of successful defibrillation" as a monitor during CPR in out-of-hospital cardiac arrested patients.

The frequency spectrum of the ECG in ventricular fibrillation (VF) correlates with myocardial perfusion and might predict defibrillation success defined as return of spontaneous circulation (ROSC). The predictive power increases when more spectral variables are combined, but the complex information can be difficult to handle during the intensity of CPR. We therefore developed a method for expressing this multidimensional information in a single reproducible variable reflecting the probability of defibrillation success. This is based on the highest performing predictor for ROSC after 883 shocks given to 156 patients with VF. This was a combination of two decorrelated spectral features based on a principal component analysis of an original feature set with information on centroid frequency, peak power frequency, spectral flatness and energy. The function "Probability of defibrillation success" (P(ROSC)(v)) was developed by a 2-dimensional histogram technique. P(ROSC)(v) discriminated between shocks followed by ROSC and No-ROSC (P<0.0001). The present methodology indicates a possible way to develop a CPR monitor.

Cardiopulmonary Resuscitation↗

Optimal filter-based detection of microcalcifications.

This paper deals with the problem of texture feature extraction in digital mammograms. We use the extracted features to discriminate between texture representing clusters of microcalcifications and texture representing normal tissue. Having a two-class problem, we suggest a texture feature extraction method based on a single filter optimized with respect to the Fisher criterion. The advantage of this criterion is that it uses both the feature mean and the feature variance to achieve good feature separation. Image compression is desirable to facilitate electronic transmission and storage of digitized mammograms. In this paper, we also explore the effects of data compression on the performance of our proposed detection scheme. The mammograms in our test set were compressed at different ratios using the Joint Photographic Experts Group compression method. Results from an experimental study indicate that our scheme is very well suited for detecting clustered microcalcifications in both uncompressed and compressed mammograms. For the uncompressed mammograms, at a rate of 1.5 false positive clusters/image our method reaches a true positive rate of about 95%, which is comparable to the best results achieved so far. The detection performance for images compressed by a factor of about four is very similar to the performance for uncompressed images.

Biomedical Engineering↗

CPR artifact removal from human ECG using optimal multichannel filtering.

The purpose of this study was to assess whether the artifacts presented by precordial compressions during cardiopulmonary resuscitation could be removed from the human electrocardiogram (ECG) using a filtering approach. This would allow analysis and defibrillator charging during ongoing precordial compressions yielding a very important clinical improvement to the treatment of cardiac arrest patients. In this investigation we started with noise-free human ECGs with ventricular fibrillation (VF) and ventricular tachycardia (VT) records. To simulate a realistic resuscitation situation, we added a weighted artifact signal to the human ECG, where the weight factor was chosen to provide the desired signal-to-noise ratio (SNR) level. As artifact signals we used ECGs recorded from animals in asystole during precordial compressions at rates 60, 90, and 120 compressions/min. The compression depth and the thorax impedance was also recorded. In a real-life situation such reference signals are available and, using an adaptive multichannel Wiener filter, we construct an estimate of the artifact signal, which subsequently can be subtracted from the noisy human ECG signal. The success of the proposed method is demonstrated through graphic examples, SNR, and rhythm classification evaluations.

Biomedical Engineering↗

Optimisation algorithms for ECG data compression.

The use of exact optimisation algorithms for compressing digital electrocardiograms (ECGs) is demonstrated. As opposed to traditional time-domain methods, which use heuristics to select a small subset of representative signal samples, the problem of selecting the subset is formulated in rigorous mathematical terms. This approach makes it possible to derive algorithms guaranteeing the smallest possible reconstruction error when a bounded selection of signal samples is interpolated. The proposed model resembles well-known network models and is solved by a cubic dynamic programming algorithm. When applied to standard test problems, the algorithm produces a compressed representation for which the distortion is about one-half of that obtained by traditional time-domain compression techniques at reasonable compression ratios. This illustrates that, in terms of the accuracy of decoded signals, existing time-domain heuristics for ECG compression may be far from what is theoretically achievable. The paper is an attempt to bridge this gap.

Algorithms↗

Computationally efficient sub-band coding of ECG signals.

A data compression technique is presented for the compression of discrete time electrocardiogram (ECG) signals. The compression system is based on sub-band coding, a technique traditionally used for compressing speech and images. The sub-band coder employs quadrature mirror filter banks (QMF) with up to 32 critically sampled sub-bands. Both finite impulse response (FIR) and the more computationally efficient infinite impulse response (IIR) filter banks are considered as candidates in a complete ECG coding system. The sub-bands are threshold, quantized using uniform quantizers and run-length coded. The output of the run-length coder is further compressed by a Huffman coder. Extensive simulations indicate that 16 sub-bands are a suitable choice for this application. Furthermore, IIR filter banks are preferable due to their superiority in terms of computational efficiency. We conclude that the present scheme, which is suitable for real time implementation on a PC, can provide compression ratios between 5 and 15 without loss of clinical information.

Algorithms↗