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Biomedical subjects

J H Helderman

Publications and source records attributed to J H Helderman.

112 records · Page 7Linked to original sources
PubMedDate not supplied

The insulin receptor on activated immunocompetent cells.

This article reviews the corpus of work on the activated T lymphocyte insulin receptor begun in the laboratory of Dr. Reubin Andres. It reviews the pharmacokinetic properties of the lymphocyte insulin receptor and the mechanisms by which the receptor is regulated on the cell. An immunobiologic role for insulin and its receptors is described. Lastly, a novel monokine responsible for fine regulation of the T lymphocyte insulin receptor is described which might be an important immunosuppressant molecule for future studies.

Humans↗
PubMedDate not supplied

Epidemic renal transplant rejection associated with influenza A victoria.

1) IAV infection seems to trigger acute renal allograft rejection frequently, especially in the first few months post-transplant, and these rejections are severe with a high rate of ultimate graft loss; 2) seroconversion occurred in most cases despite high dose steroids; 3) the course of IAV was prolonged and associated with a high incidence of complications in patients on high dose steroids.

Adult↗