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Biomedical subjects

J H Harris

Publications and source records attributed to J H Harris.

At least 73 records · Page 4Linked to original sources

Effect of phenytoin on functional recovery after experimental spinal cord injury in dogs.

We injured 26 dogs by dropping a 25-g, flat-bottomed weight directly onto the exposed dura. Dogs treated with phenytoin (PHT) were clinically superior to untreated controls when compared 6 weeks after injury. Comparison between PHT and dexamethasone reveals that PHT is at least as effective. The therapeutic effectiveness of PHT treatment begun immediately after injury and begun 30 minutes later was evaluated. The results obtained in all three treated groups of dogs were superior to the results with untreated controls at a significance level of P < 0.01.

Animals↗

Teaching cost containment to house officers at Charlotte Memorial Hospital.

A cost containment program initiated in 1975 on the medical teaching service of an 890-bed university affiliated hospital has led to a significant improvement in house staff utilization of facilities and procedures. During the first three and one-half years of the program the average length of stay on the general medical service was reduced by 21 percent; and the cost per admission rose at a rate of only 4.3 percent per annum, while the cost per admission on other services rose at an average rate of 14.5 percent per year. In the outpatient setting eliminating unnecessary laboratory procedures resulted in an actual reduction in patient-encounter cost initiated by interns despite price increases on all procedures. Overall cost advantage gained by reduction in utilization will rapidly be negated, however, if the current rate of inflation continues.

Cost Control↗

An improved method for localization of nonpalpable breast lesions.

Insertion of a hooked stylet into the region of a mammographic abnormality is a simple method of localization prior to biopsy. The hook on the stylet does not permit movement of the localization device away from the lesion during the interval between placement and surgical excision. A xeroradiograph of the biopsy specimen determines whether the suspected region was obtained surgically.

Biopsy↗

Cementoenamel defects in an unusual location.

An unusual case involving cementoenamel defects was discussed. These defects appeared as vertical grooves at the cervical margins on the facial surfaces of the maxillary incisors. They have caused no pulpal or periodontal problems.

Adult↗

Brain death: II. Neuropathological correlation with the radioisotopic bolus technique for evaluation of critical deficit of cerebral blood flow.

Diffuse necrosis and autolysis were found in the brains from 6 comatose, respirator-supported patients in whom the bolus technique demonstrated no cerebral blood flow during a period exceeding 20 hours prior to cardiac death. When blood flow was insufficient to produce a bolus, there was no evidence of active tissue response to necrosis. In 6 similar patients, when cerebral blood flow was detected by the bolus technique, less extensive necrosis was observed postmortem and there was active tissue response.

Apnea↗

The roentgen diagnosis of pelvic extraperitoneal effusion.

Extraperitoneal, perivesical pelvic effusions may be hemorrhagic or uriniferous, the latter resulting from extraperitoneal rupture of the bladder or disruption of the posterior urethra. The effusions may be recognized on anteroposterior radiographs of the pelvis by (a) displacement of the bladder (small effusion); (b) obliteration of the normal soft-tissue anatomy within the pelvis (moderate effusion); and (c) upward displacement of the pelvic ileal loops and extension of the effusion into the flank stripes (large effusion). Perivesical effusions most frequently accompany anterior pelvic arch injuries, i.e., double vertical and Malgaigne fractures and fractures involving, or separation of, the pubic symphysis.

Female↗

Experiential education for dental students at the University of Kentucky.

An experiential educational system at the University of Kentucky College of Dentistry has been described. It consists of a summer externship program and an individualized externship program offered during the academic year. These programs provide dental students with extramural educational experiences in private dental offices to prepare them better for the practice of dentistry and to expose them to forces affecting the delivery of dental services.

Education, Dental↗

The significance of soft tissue injury in the roentgen diagnosis of trauma.

Soft tissue damage is an integral part of trauma. This basic fact is commonly ignored in the evaluation of roentgenograms obtained because of trauma. The soft tissue component of the traumatic lesion may produce the most obvious roentgen sing of injury and is, in these instances, fundamental to the correct roentgen diagnosis. In many instances, the soft tissue lesion is frequently of greater clinical significance that the more obvious skeletal injury. An awareness of the roentgen signs that signal soft tissue injury, and of those skeletal lesions that are commonly associated with radiographically silent, but clinically more significant, soft tissue damage, leads to prompt institution of appropriate additional diagnostic studies or therapeutic measures. Thus, the soft tissue injury in the roentgen diagnosis of trauma has both diagnostic and therapeutic significance. Each will be discussed in this article.

Abdominal Injuries↗