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Biomedical subjects

J H Hansen

Publications and source records attributed to J H Hansen.

At least 37 records · Page 2Linked to original sources
PubMed1984

Failure of proximal gastric vagotomy for duodenal ulcer resistant to cimetidine.

45 patients with uncomplicated duodenal ulcer who did not respond to cimetidine underwent elective proximal gastric vagotomy (PGV). 39 of these, who had received cimetidine for an average of 5.2 months before surgery, were followed up for 20-67 months postoperatively. 18(46%) of them were classified as grade IV (ie, failures) according to a modified Visick scale--17 (44%) had a recurrent peptic ulcer. Augmented histamine tests done in 17 patients showed an expected reduction of peak acid output, so maintenance of stomach acidity was unlikely to be a cause of failure of the operation. The presence of mental and social problems preoperatively was associated with a postoperative Visick grade IV. Despite repeated medical therapy, and reoperation in 6 patients, 10(26%) patients still had severe pain and/or dumping at follow up. Proximal gastric vagotomy cannot be advocated in patients with uncomplicated duodenal ulcer resistant to cimetidine, and an alternative treatment is needed for these patients.

Adult↗
PubMed1984

The "axial sacroiliac joint".

This article describes an iliac prominence and a sacral cavity, located extracapsularly approximately 15 mm dorsal to the angle created by the auricular facies of the sacroiliac joint. These bony structures are often covered by cartilage on one side, usually on the iliac prominence. The sacral cavity is occupied by areolar tissue, rich in adipocytes. They interface very closely, forming an extracapsular junction, which we have named the "axial sacroiliac joint". The study comprised 27 anatomical specimens, 3 of which were found to be ankylosed. Among the remaining 24, and iliac prominence was demonstrated on 22, and a sacral cavity on all. Descriptions and measurements of the sacroiliac joint, the "axial sacroiliac joint", and the spatial relationships are presented, the sacroiliac joint being the joint of reference. The study includes microscopy of the "axial sacroiliac joint".

Humans↗
PubMed1983

Prophylactic treatment of classical and non-classical migraine with metoprolol--a comparison with placebo.

A double-blind investigation with parallel groups was carried out in three Danish neurological clinics to evaluate the effect of metoprolol (Beloc, Betaloc, Seloken) versus placebo in migraine patients. 71 patients were included; 62 completed the study. The following parameters were used in the evaluation: frequency of headache attacks, days with migraine, severity score (days X intensity), and the consumption of pain-relieving tablets. The results of the study show that metoprolol 200 mg in Durules (a controlled release formulation) once daily is more effective regarding all evaluated parameters than placebo and that metoprolol is well tolerated.

Adolescent↗
PubMed1982

Acupuncture treatment of chronic unilateral tinnitus--a double-blind cross-over trial.

In a double-blind controlled trial the effect of traditional Chinese acupuncture versus placebo acupuncture was evaluated among 17 patients (8 females and 9 males, mean age 45.7 years) with chronic (mean disease duration 5.3 years) unilateral tinnitus. None of the patients had any treatable otological disease. All patients suffered from daily tinnitus, the intensity of which was recorded by the patients themselves every day during a period of 15 weeks. Each patient was treated by traditional Chinese acupuncture as well as placebo acupuncture following randomization (Figure 1). Each period of treatment comprised 2 treatments a week for 3 weeks. Throughout the whole investigation a period effect was recorded, insignificant in the acupuncture-placebo group, but significant in the placebo-acupuncture group (Friedman analysis of variance) (Table 4). There was no significant difference between traditional Chinese acupuncture and placebo (Wilcoxon test, P greater than 0.05, one-tailed). There was no relation between the patients' subjective statements and the results of sound balance measurements as an objective standard of tinnitus (Spearman test).

Acupuncture Therapy↗
PubMed1982

Platelet aggregation in focal cerebral ischemia -a clinical study.

In a consecutive series of 35 patients with transient ischemic attacks (TIAs) 26 patients (74%) had pathological platelet aggregation 4 weeks after the latest TIA. Pathological platelet aggregation was the most frequent factor leading to a prophylactic treatment of the TIAs. Among 12 patients with reversible ischemic neurological deficit (RIND) only one had pathological platelet aggregation, and among 54 patients with completed stroke 37% had pathological platelet aggregation 4 weeks after the cerebral infarction. It is possible by the antiaggregating agents acetylsalicylic acid and dipyridamole to normalize in vitro pathological platelet aggregation. The frequency of side effects was low. During this treatment further TIAs were stopped in 17/19 patients, and remission were seen in 14/14 stroke patients. Compared with the remissions during treatment with anticoagulants there was a tendency of more favourable outcome in the group of stroke patients when treated with antiaggregating agents.

Adult↗
PubMed1979

DDAVP, a synthetic analogue of vasopressin, in prevention of headache after lumbar puncture and lumbar pneumoencephalography.

In a double-blind controlled trial the possible prophylactic effect of intranasally applicated DDAVP (1-desamino-8-arginine vasopressin, Minurin)--a synthetic analogue of vasopressin--is evaluated regarding the incidence of headache following lumbar puncture (LBP) in 51 patients and following pneumoencephalography (PEG) in 28 patients. DDAVP had no statistically significant effect on the incidence of headache or on the consumption of analgesics in the DDAVP-versus placebo groups (minimal relevant difference = 50%, 2 alpha = 0.05, beta = 0.50).

Adult↗