Search PubMed⌕ Search

Biomedical subjects

J H Friedman

Publications and source records attributed to J H Friedman.

At least 145 records · Page 8Linked to original sources

Hypotension due to glossopharyngeal neuralgia.

We studied two cases of glossopharyngeal neuralgia with hypotension and syncope. A patient undergoing carotid angiography suffered glossopharyngeal neuralgia, bradycardia, and hypotension due to a hematoma from a subintimal injection of dye. The second patient developed glossopharyngeal neuralgia with hypotension in the absence of bradycardia due to a metastatic head and neck tumor. This patient's hypotension was refractory to the administration of atropine sulfate and occurred in the presence of sinus tachycardia, suggesting that baroreceptor vasodepressor activity was selectively elevated.

Bradycardia↗

A case of progressive hemichorea responsive to high-dose reserpine.

A 74-year-old woman developed a slowly progressive hemichorea starting 3 weeks after discontinuation of low-dose amitriptyline and perphenazine. The duration of neuroleptic exposure was 3 months. The chorea was initially well controlled on 5.25 mg/day of reserpine, but after 21 months, required 2.0 mg/day. No complications of reserpine occurred.

Aged↗

A neuroleptic malignantlike syndrome due to levodopa therapy withdrawal.

Three cases of a syndrome resembling neuroleptic malignant syndrome are described in patients never exposed to neuroleptics. Each patient had a long history of Parkinson's disease treated with a carbidopa-levodopa combination. Two patients developed the syndrome when administration of the drug was discontinued temporarily. One developed the syndrome before the "drug holiday," and then died during the holiday because of this complication.

Aged↗

'Drug holidays' in the treatment of Parkinson's disease. A brief review.

"Drug holiday," the withdrawal of levodopa for a variable period of time, is a controversial method of treating patients with Parkinson's disease who have levodopa-related complications. Only four studies have been published in which patients were observed for one year or longer. Although it is extremely beneficial for some patients, this treatment provides a sustained one-year benefit for only a minority of patients.

Aged↗

Bilateral facial palsy associated with Stevens-Johnson syndrome.

A 22-year-old man developed acute bilateral peripheral facial paralysis in association with Stevens-Johnson syndrome, probably as a result of ampicillin allergy. All symptoms cleared except the facial paralysis. He is the first patient in whom acute facial palsy and Stevens-Johnson syndrome have occurred simultaneously.

Adult↗