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Biomedical subjects

J H Ellis

Publications and source records attributed to J H Ellis.

At least 109 records · Page 6Linked to original sources

Anomalous pulmonary venous drainage of the left upper lobe shown by CT scans.

Isolated anomalous drainage of the left superior pulmonary vein into the left brachiocephalic vein was shown on computed tomographic (CT) scans. The CT findings include a vertical vein lateral to the aorticopulmonary window and aortic arch that terminates in the left brachiocephalic vein. Features that differentiate this entity from left superior vena cava, anomalous left brachiocephalic vein, and superior intercostal vein are discussed.

Aged↗

Boundary effects from opposed magnetization artifact in IR images.

A cancellation of signal intensity at the interface separating selected tissue-equivalent materials is observed in inversion recovery proton MR images. The absence of signal intensity at the interface is always one pixel wide and appears only when the tissue-equivalent materials forming the interface differ substantially in their longitudinal relaxation times (T1). Images were obtained of various two-layer combinations of tissue-equivalent materials consisting of vegetable oil, animal fat, saline, aqueous Mn+2, or 2% agar doped with Mn+2. This type of boundary is compared with chemical shift artifacts, which at 0.15 T and 0.35 T produce a similar effect. A clinical example of the opposed magnetization artifact is also shown. Since tissues with substantially different T1s are found in vivo, it is expected that this effect could lead to an instrument-dependent artifact that could easily be misinterpreted.

Electron Spin Resonance Spectroscopy↗

Pitfall in MR imaging of lymphadenopathy after lymphangiography.

In two patients examined with magnetic resonance (MR) imaging after lymphangiography, opacified pelvic lymph nodes could not be distinguished from subcutaneous or retroperitoneal fat because of the short T1 and long T2 relaxation times of lymphangiographic contrast media. Opacified nodes removed from one patient had relaxation times similar to those of fat. Thus, assessment of lymphadenopathy with MR imaging should be performed before lymphangiography to obviate this potential pitfall.

Contrast Media↗

Impact of myelography on the radiotherapeutic management of malignant spinal cord compression.

From December 1981 through August 1984, 24 patients with spinal cord compression syndrome due to epidural neoplasms were evaluated for radiotherapy with clinical examination, radiographs of the spine, and myelography. All plain films were reviewed, and mock radiotherapy fields designed using specific criteria for margins. The same patients were reviewed a second time considering the additional information provided by myelography. The initial treatment fields were found to be inadequate in 69% of the patients. Even in patients with discrete bony lesions, the results of myelography affected the treatment 45% of the time. A history of previous spinal irradiation significantly influenced port design in only 1 of the 7 patients who had received previous radiotherapy. Although invasive, myelography is essential in planning the treatment of spinal cord compression.

Adult↗

Lymphoid tumors of the ocular adnexa. Clinical correlation with the working formulation classification and immunoperoxidase staining of paraffin sections.

Eighty-eight patients with ocular adnexal lymphoid lesions examined at the Mayo Clinic between 1970 and 1982 were evaluated. The histopathologic type was reclassified using the working formulation. Paraffin sections were evaluated with immunoperoxidase staining. There were 11 "pseudotumors" and 77 lymphomas. Sixty lymphomas were small lymphocytic type A; 27 tissues had a monoclonal staining pattern, and 4 had a polyclonal staining pattern. Five of the pseudotumors had a polyclonal staining pattern; none had a monoclonal pattern. The remainder did not stain or tissue was not available. Thirty-six of the 44 lymphomas that presented in the ocular adnexa remained localized. There were no distinguishing features between conjunctival and orbital lymphomas. Significant damage to the ocular tissue occurred in 15 of the 63 patients treated with radiation therapy. Older, asymptomatic patients with a favorable histologic type may not require treatment; therapy is reserved for specific indications. The probability of survival to five or seven years differs little from that expected in the general population.

Adolescent↗

Comparison of NMR and CT imaging in the evaluation of metastatic retroperitoneal lymphadenopathy from testicular carcinoma.

Twenty-five patients with nonseminomatous germ cell carcinoma of the testis underwent CT and nuclear magnetic resonance (NMR) of the retroperitoneum followed by radical retroperitoneal lymph node dissection for surgical proof of metastatic disease. Computed tomography correctly predicted the presence or absence of adenopathy in 88% and assigned the correct stage in 84%. Nuclear magnetic resonance had comparable figures of 84 and 80%. Computed tomography appeared superior to NMR in detecting other abdominal abnormalities, although these were few in number. Nuclear magnetic resonance is nearly equivalent to CT in staging retroperitoneal lymphadenopathy from testicular cancer and may surpass CT following technical advances and the introduction of oral contrast agents.

Adolescent↗

Assessment of primary gynecologic malignancies: comparison of 0.15-T resistive MRI with CT.

Thirty-eight patients with gynecologic malignancies (ovarian, cervical, and endometrial carcinoma) underwent computed tomography (CT) and magnetic resonance imaging (MRI) of the abdomen and pelvis. Results of these studies were compared with each other as well as with clinical staging and surgical findings when possible. CT and MRI correctly staged 64% (nine of 14) of patients with cervical carcinoma. In patients suspected of residual or recurrent disease, CT and MRI were each correct in 75% (15 of 20), four of the errors being due to inability to distinguish inflammation or radiation changes from recurrent tumor. CT and 0.15-T resistive MRI are of equal value in screening for residual or recurrent disease and as an adjunct to clinical staging; further advances in MRI technology may alter this impression.

Adult↗

Experimental lung nodule model: CT numbers, nodule size, and actual calcium content.

An experimental pulmonary nodule model was developed to study the effect of nodule size, nodule environment, and calcium content on the attenuation values in two computed tomography (CT) scanners. The experimental results show that (a) calcium is the moiety most responsible for the CT number, (b) small nodules may have falsely low CT numbers, (c) CT numbers vary from scanner to scanner when scanning the same nodule, and (d) higher CT numbers are obtained when experimental nodules are scanned in air rather than water.

Calcinosis↗

"Cold spot" on bone scan at the site of primary osteosarcoma.

A 5-year-old girl presented with a rapidly growing osteosarcoma of the proximal right tibia. The radiographically osteoblastic lesions appeared as a "cold" on the 99mTc-MDP bone scan. Possible explanations for this unusual finding on the bone scan are discussed.

Bone Neoplasms↗