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Biomedical subjects

J H Clark

Publications and source records attributed to J H Clark.

At least 289 records · Page 16Linked to original sources
PubMed1970

Ontogeny of the estrogen receptor during early uterine development.

The number of estrogen binding sites in uterine cytoplasm on a per cell basis reaches a maximum by day 10 of life in both intact and castrate female rats. After this peak is reached, the number of binding sites per cell decreases, and the ratio remains constant until days 22 to 23 of life. Thus, the ontogeny of the estrogen binding protein is not dependent upon estrogen from the ovary and is probably an autonomous property of uterine cells. Sedimentation values and dissociation constants of the protein when the animals are 5 to 10 days of age are similar to those of the 22-day-old animal, indicating that the same protein is present throughout postnatal development.

Age Factors↗
PubMed1969

The art of virtue.

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Ethics, Medical↗
PubMed1968

Pregnancy following coital-induced ovulation in a spontaneous ovulator.

Ovulation induced in the immature rat by pregnant mare's serum can be prevented by chlorpromazine. Coitus induces ovulation in such animals, and ovulation so induced may result in pregnancy. Both implantation and pregnancy appear to be normal although the duration of gestation may be prolonged. Decidual response also is produced in the immature rat after coitus-induced ovulation. We suggest that the reflex release of luteinizing hormone may occur in Primates after coitus.

Animals↗