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Biomedical subjects

J H Boss

Publications and source records attributed to J H Boss.

172 records · Page 10Linked to original sources
PubMedDate not supplied

Computer-assisted image analysis of small cell lymphoma of the thyroid gland. Comparison of nuclear parameters of small lymphocytes in lymphomas and Hashimoto's thyroiditis.

The nuclear parameters of the small lymphocytes in nine cases of small cell lymphomas of the thyroid gland and 17 cases of Hashimoto's thyroiditis were assessed by computer-assisted image analysis. The nuclear area, maximal, minimal and averaged Ferret diameters, perimeter, regularity factor and elongation factor were gauged. Statistically, the nuclear area was ascertained to be the optimum descriptor discriminating between small neoplastic and reactive lymphocytes. Application of a novel variable, combining a nuclear area cut-off value of 14 microm2 with a nuclear averaged Ferret diameter cut-off value of 4.5 micron, allows for the distinction - with a high degree of sensitivity and specificity - between small neoplastic lymphocytes in thyroidal lymphomas and the reactive lymphocytes in Hashimoto's thyroiditis.

Adult↗
PubMedDate not supplied

The fasciitis-panniculitis syndrome presenting as complex regional pain syndrome type 1: report of a case.

A 28-year-old man presented with a clinical picture suggestive of complex regional pain syndrome type I following a blow to the thenar eminence and thumb. Symptoms, including swelling of the hand and distal forearm, progressed until an amputation was carried out to rid the patient of an unendurable painful and nonfunctioning wrist and hand. The histologic evaluation of the amputation specimen showed: 1) dermal edema, perivascular dermatitis, and epidermal hyperkeratosis; 2) subcutaneous chronic inflammation with subtotal replacement of the adipose lobules by fibrous tissue associated with thickening of the muscular fascia, implying the fasciitis-panniculitis reaction pattern; 3) atrophy, degeneration, necrosis, and focal calcifications of the skeletal muscles; 4) phlebosclerosis, phlebectasias and lymphocytic arteritis; and 5) increased cortical porosity of the bones. It seems that the pathogenetic process underlying the fasciitis-panniculitis syndrome may rarely manifest as a complex regional pain syndrome-like disorder.

Adult↗
PubMedDate not supplied

Coincident Warthin's tumor and intraparotid dermatopathic lymphadenopathy. Report of a case.

A 52-year-old patient underwent excision of a parotid lump which was fond to consist of a Warthin's tumor coexistent with a lymph node involved in dermatopathic lymphadenopathy. A preoperative fine-needle aspiration specimen contained brown pigment-granule-laden macrophages within the background of many lymphocytes. Failure to correctly diagnose the parotid tumor was likely due to a sampling error.

Adenolymphoma↗
PubMedDate not supplied

Rational and cost-effective management of the patient with a solid breast lump.

The rational management of the palpable breast lump requires a tissue diagnosis. The more conventional approach is biopsy under general anesthesia, examination of frozen sections and "follow-on" mastectomy when indicated. In the present study, we aimed at arriving at an unequivocal tissue diagnosis by studying permanent sections at a separate ambulatory procedure either with formal biopsy under local anesthetic or, in suspicious lumps, with the Trucut biopsy needle (Travenol Laboratories, Inc. USA). Only 7 (14%) of the 56 women with 64 breast lumps were hospitalized for biopsy under general anesthesia. In 13 out of 22 breast cancers, the definitive diagnosis was made by examining Trucut needle biopsy specimens. This alternative approach provides a significant reduction of costs, more efficient utilization of operating time and a fully evaluated, psychologically prepared patient, when mastectomy is indicated.

Adolescent↗