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Biomedical subjects

J H Allen

Publications and source records attributed to J H Allen.

At least 37 records · Page 2Linked to original sources
PubMed1979

Subdural hygroma: diagnosis with computed tomography.

Nine cases are reported that fulfilled the criteria for diagnosis of subdural hygroma. With the availability of serial computed tomographic (CT) scans, it is possible to document non-invasively the appearance of CSF-density subdural fluid where no prior blood accumulation has been present.

Adolescent↗
PubMed1979

Computed tomography in cerebellar atrophic processes.

Forty-six patients with cerebellar atrophy were identified by review of CT scans of 7,500 patients. Independent examination of a separate file of the same group disclosed 49 patients whose history indicated cerebellar degeneration. Forty-three patients were in both groups indicating excellent correlation between CT abnormality and clinical cerebellar signs. Three patients with CT cerebellar atrophy failed to show clinical cerebellar signs, and 6 had clinical signs without evidence of changes on CT. Specific anatomic correlation was suggested in 10 of 13 patients with predominantly midline cerebellar CT abnormalities, and in 3 with olivopontocerebellar degeneration clinically who showed brainstem and cerebellar atrophy.

Atrophy↗
PubMed1978

Controlled use of cranial computerized tomography.

This study attempts to assess the impact of computerized cranial tomography (CT) on clinical practice in a veterans hospital. A CT scan could be performed only if there existed a reasonable potential for the results to affect the patient's clinical course. We document many instances of how the 163 CT scans obtained during a one-year period aided patients. We quantitated one beneficial aspect by estimating the major neuroradiologic contrast procedures obviated by CT scan. Case-by-case review indicates 70 cerebral arteriograms and 58 pneumoencephalograms would have been performed had CT scanning not been available.

Adolescent↗
PubMed1978

The role of hemolysin in corneal infections with Pseudomonas aeruginosa.

Cultures of Pseudomonas aeruginosa considered to be of proven virulence were found to have higher titers of extracellular hemolysin than cultures of lesser virulence. Intracorneal injection of purified hemolysin produced extensive corneal opacification with extensive leukocytic infiltration of the tissue. It is suggested that the hemolysin plays a role in the pathogenesis of P. aeruginosa infections by effecting lysis of host cells and/or subcellular organelles, leading to the release of enzymes destructive to corneal tissue.

Animals↗
PubMed1975

The role of cytolysin in pneumococcal ocular infection.

A highly purified preparation of pneumococcal cytolysin was responsible for the corneal damage that ensued upon intra-corneal injection of crude cell extract into the rabbit eye. The lysin may produce this pathologic finding by effecting activation or release of corneal degradative enzymes.

Animals↗