Search PubMed⌕ Search

Biomedical subjects

J Grochowski

Publications and source records attributed to J Grochowski.

47 records · Page 3Linked to original sources

Comparative investigations of hydroxyamine carane derivative and its R,S-diastereoisomers with strong local anesthetic activity.

Our previously conducted pharmacological screening led as to the discovery of the strong local anesthetic activity of the compound designated as KP-23. Earlier crystallographic studies revealed that the compound KP-23 crystallized in diastereoisomeric form in lowest symmetry. The aim of these comparative investigations was to evaluate anesthetic activity of KP-23 and its R,S-diastereoisomers, which were synthesized at the Institute of Organic Chemistry, Biochemistry and Biotechnology, Wroclaw University of Technology.

Anesthetics, Local↗

[Orbital myositis].

Four patients with unspecific myositis of the extraocular muscles were treated in the Ophthalmological Department Medical School in Białystok in the period 1983-1988. The authors discuss the problems connected with the diagnosis and treatment of this pathological condition. Special attention is called to the new diagnostic methods.

Aged↗