Search PubMed⌕ Search

Biomedical subjects

J Grant

Publications and source records attributed to J Grant.

177 records · Page 10Linked to original sources
PubMedDate not supplied

Burns of children caused by electric stoves.

During a 2-year period, eight patients sustained burns caused by the tipping over of electric stoves. In seven of these cases, children aged 2 to 4 years stood up on the open oven door of a stove. The stove then tipped forward, and a pot of boiling liquid on the stove spilled onto the child, who fell forward across the oven door. The general area of involvement was back and buttocks, with spattered areas elsewhere on the body. In one other case, an older child, aged 8, sat on the open oven door and was burned when a pot fell on him. The weight of the children ranged from 12.7 to 20 kilograms, with a mean of 15.2 kilograms. The 8-year old weighed 14.9 kilos. Burn size ranged from 3% to 30%, with a mean of 16.75%. All burns were second-degree and were treated by debridement and coverage with either porcine grafts or Biobrane (Dow Hickman Pharmaceuticals, Inc.). Healing was satisfactory in all cases. Hospital stay ranged from 2 to 20 days. The increase in the use of electric stove has led to a situation in which children, usually toddlers, can overbalance the stove and bring down the pots sitting on the heating elements. This represents another mechanism by which young children can be injured in the kitchen; the awareness of this should be disseminated.

Bandages↗
PubMedDate not supplied

Surgical and nonpsychiatric medical treatment of patients with body dysmorphic disorder.

It appears that many individuals with body dysmorphic disorder (BDD) receive nonpsychiatric medical treatment and surgery; however, this topic has had little systematic investigation. This study assessed the nonpsychiatric treatment sought and received by 289 individuals (250 adults and 39 children/adolescents) with DSM-IV BDD. Such treatment was sought by 76.4% and received by 66.0% of adults. Dermatologic treatment was most often received (by 45.2% of adults), followed by surgery (by 23.2%). These treatments rarely improved BDD symptoms. Results were similar in children/adolescents. These findings indicate that a majority of patients with BDD receive nonpsychiatric treatment but tend to respond poorly.

Adolescent↗
PubMedDate not supplied

Spotting diabetes.

Explore the source record for details and available documents.

Diabetes Mellitus, Type 2↗
PubMedDate not supplied

[A pilot community study of subjective memory in over and under 65 years old].

Elderly adults are appropriate targets for objective memory assessment and cognitive testing in the promotion of earlier recognition of people with symptoms of a dementing process. The major change in memory with age is the decline in ability to recall things explicitly. There is a need for education of the general public and health professionals about memory impairment and its relationship with stress, depression, anxiety and dementia.

Adult↗
PubMedDate not supplied

Lonely at the top.

Explore the source record for details and available documents.

Female↗
PubMedDate not supplied

H-77: a potent new renin inhibitor. In vitro and in vivo studies.

Chemical modification of the backbone at the cleavage site in the (6-13)-octapeptide of equine angiotensinogen resulted in greatly increased binding affinity and resistance to cleavage by renin. The D-His6-Tyr13 octapeptide analog containing the reduced bond -CH2-NH-instead of a peptide bond -CO-NH- at the Leu10-Leu11 linkage (H-77) was a powerful in vitro inhibitor of canine renin (IC50 = 24nM). It gave an IC50 of 1 microM against human renin and 0.6 microM against rat renin. In sodium-depleted conscious dogs, infusion of H-77 caused dose-related falls of plasma angiotensin I plasma angiotensin II concentration and mean arterial pressure; the minimum effective dose was 0.1 mg . kg-1 hr-1. Similar infusions of H-77 in chronically catheterized rats have no effect on blood pressure or plasma angiotensin II concentration. Thus, the in vitro effect of H-77 as an inhibitor of renin in dog, human, and rat plasma was paralleled by its action in the whole animal.

Angiotensin I↗
PubMedDate not supplied

Comparability of English and Welsh doctor of medicine degrees.

A comparison of the regulations required for the degree of Doctor of Medicine revealed wide variations between different universities, e.g. candidates may not receive much supervision or structured teaching. Universal reform is needed to bring this degree in line with the degree of Doctor of Philosophy.

Academic Dissertations as Topic↗
PubMedDate not supplied

MD candidates want better training in research.

A survey of MD candidates in one teaching hospital and two postgraduate institutes was undertaken to determine their initial training needs, and their preferred methods of learning about the conduct of research. Fifty-six respondents (53% response rate) replied to a piloted questionnaire. Their replies indicated a need for intensive initial research training, offered at local level by the supervisor. The supervisor's subsequent role throughout the research period should be to provide ongoing specific critical help and support. It is concluded that teaching materials and designed teaching sessions might be provided for supervisors to assist them in their new role.

Attitude of Health Personnel↗
PubMedDate not supplied

Radiofrequency catheter ablation for supraventricular tachycardia.

Radiofrequency catheter-mediated ablation is a recently developed technique of achieving cure of certain rhythm disorders, notably supraventricular tachycardia. In less than a decade, it has evolved from a theoretic concept to first line therapy for many patients, including those in the pediatric age group. The most common types of arrhythmias amenable to catheter ablation include supraventricular tachycardia due either to an accessory pathway or A-V nodal reentry and atrial fibrillation with a rapid ventricular response refractory to medical therapy. Before the development of the technique, the only therapeutic options included either lifelong antiarrhythmic drugs or open heart surgery. The initial experiences with catheter ablative techniques used direct current shocks of up to 400 J, delivered to an intracardiac catheter from a standard defibrillator. This energy source has largely been replaced by radiofrequency current because of the substantially lower morbidity and greater efficacy. The treatment of patients with these tachyarrhythmias is evolving from a palliative approach to a curative one. With the current worldwide experience, complications are relatively rare and do not appear to differ from those associated with routine electrophysiologic testing or cardiac catheterization. The success rate is high, usually exceeding a 90% efficacy, but is dependent on the skill and experience of the operator. The technique, arrhythmias amenable to treatment, and the nursing implications before, during, and after the procedure are discussed in this article.

Catheter Ablation↗